Publications by authors named "Kevin French"

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Opportunities and challenges for use of minipigs in nonclinical pharmaceutical development: Results of a follow-up IQ DruSafe survey.
David O Clarke, Kaushik Datta, Kevin French, Michael W Leach, Drew Olaharski

Regul Toxicol Pharmacol· December 2024

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Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.
Leo R Fitzpatrick, Cecelia Green, Elizabeth E Frauenhoffer, Kevin J French, Yan Zhuang

Inflammopharmacology· April 2011

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Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity.
Kevin J French, Robert W Coatney, Jon P Renninger, Catherine X Hu, Tracy L Gales

Toxicol Pathol· August 2010

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Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2.
Kevin J French, Yan Zhuang, Lynn W Maines, Peng Gao, Wenxue Wang

J Pharmacol Exp Ther· April 2010

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Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase.
Lynn W Maines, Leo R Fitzpatrick, Kevin J French, Yan Zhuang, Zuping Xia

Dig Dis Sci· April 2008

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Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases.
Lynn W Maines, Kevin J French, Ellen B Wolpert, David A Antonetti, Charles D Smith

Invest Ophthalmol Vis Sci· November 2006

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Antitumor activity of sphingosine kinase inhibitors.
Kevin J French, John J Upson, Staci N Keller, Yan Zhuang, Jong K Yun

J Pharmacol Exp Ther· August 2006

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Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis.
Charles E Ducker, John J Upson, Kevin J French, Charles D Smith

Mol Cancer Res· August 2005

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Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.
Charles E Ducker, Erin M Stettler, Kevin J French, John J Upson, Charles D Smith

Oncogene· December 2004

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Development of a syngeneic in vivo tumor model and its use in evaluating a novel P-glycoprotein modulator, PGP-4008.
Brian D Lee, Kevin J French, Yan Zhuang, Charles D Smith

Oncol Res· May 2004

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Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-based inhibitors of human N-myristoyltransferase-1.
Kevin J French, Yan Zhuang, Randy S Schrecengost, Jean E Copper, Zuping Xia

J Pharmacol Exp Ther· April 2004

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Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein.
Brian D Lee, Zhanjiang Li, Kevin J French, Yan Zhuang, Zuping Xia

J Med Chem· March 2004

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Discovery and evaluation of inhibitors of human sphingosine kinase.
Kevin J French, Randy S Schrecengost, Brian D Lee, Yan Zhuang, Staci N Smith

Cancer Res· September 2003

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Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol.
Kevin J French, Dan A Rock, Denise A Rock, John I Manchester, Barry M Goldstein

Arch Biochem Biophys· February 2002

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