Publications by authors named "Kevin Leder"

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A statistical framework for detecting therapy-induced resistance from drug screens.
Chenyu Wu, Einar Bjarki Gunnarsson, Jasmine Foo, Kevin Leder

NPJ Syst Biol Appl· August 2025

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Limit theorems for the site frequency spectrum of neutral mutations in an exponentially growing population.
Einar Bjarki Gunnarsson, Kevin Leder, Xuanming Zhang

Stoch Process Their Appl· April 2025

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Early Circulating Tumor DNA Kinetics as a Dynamic Biomarker of Cancer Treatment Response.
Aaron Li, Emil Lou, Kevin Leder, Jasmine Foo

JCO Clin Cancer Inform· March 2025

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Parameter estimation from single patient, single time-point sequencing data of recurrent tumors.
Kevin Leder, Ruping Sun, Zicheng Wang, Xuanming Zhang

J Math Biol· October 2024

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Early ctDNA kinetics as a dynamic biomarker of cancer treatment response.
Aaron Li, Emil Lou, Kevin Leder, Jasmine Foo

bioRxiv· July 2024

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Limit theorems for the site frequency spectrum of neutral mutations in an exponentially growing population.
Einar Bjarki Gunnarsson, Kevin Leder, Xuanming Zhang

ArXiv· March 2024

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Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data.
Chenyu Wu, Einar Bjarki Gunnarsson, Even Moa Myklebust, Alvaro Köhn-Luque, Dagim Shiferaw Tadele, Kevin Leder

PLoS Comput Biol· March 2024

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Statistical inference of the rates of cell proliferation and phenotypic switching in cancer.
Einar Bjarki Gunnarsson, Jasmine Foo, Kevin Leder

J Theor Biol· July 2023

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Statistical inference of the rates of cell proliferation and phenotypic switching in cancer.
Einar Bjarki Gunnarsson, Jasmine Foo, Kevin Leder

ArXiv· June 2023

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Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data.
Alvaro Köhn-Luque, Even Moa Myklebust, Dagim Shiferaw Tadele, Mariaserena Giliberto, Leonard Schmiester, Kevin Leder

Cell Rep Methods· March 2023

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Exact site frequency spectra of neutrally evolving tumors: A transition between power laws reveals a signature of cell viability.
Einar Bjarki Gunnarsson, Kevin Leder, Jasmine Foo

Theor Popul Biol· December 2021

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Understanding the role of phenotypic switching in cancer drug resistance.
Einar Bjarki Gunnarsson, Subhajyoti De, Kevin Leder, Jasmine Foo

J Theor Biol· April 2020

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Glioblastoma Recurrence and the Role of O-Methylguanine-DNA Methyltransferase Promoter Methylation.
Katie Storey, Kevin Leder, Andrea Hawkins-Daarud, Kristin Swanson, Atique U Ahmed

JCO Clin Cancer Inform· February 2019

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A Robust Optimization Approach to Cancer Treatment under Toxicity Uncertainty.
Junfeng Zhu, Hamidreza Badri, Kevin Leder

Methods Mol Biol· October 2018

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Combination therapeutics of Nilotinib and radiation in acute lymphoblastic leukemia as an effective method against drug-resistance.
Kamran Kaveh, Yutaka Takahashi, Michael A Farrar, Guy Storme, Marcucci Guido, Kevin Z Leder

PLoS Comput Biol· July 2017

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Quantifying the Dynamics of Field Cancerization in Tobacco-Related Head and Neck Cancer: A Multiscale Modeling Approach.
Marc D Ryser, Walter T Lee, Neal E Ready, Kevin Z Leder, Jasmine Foo

Cancer Res· December 2016

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Optimized Treatment Schedules for Chronic Myeloid Leukemia.
Qie He, Junfeng Zhu, David Dingli, Jasmine Foo, Kevin Zox Leder

PLoS Comput Biol· October 2016

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Optimal treatment and stochastic modeling of heterogeneous tumors.
Hamidreza Badri, Kevin Leder

Biol Direct· August 2016

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A mathematical model of tumor growth and its response to single irradiation.
Yoichi Watanabe, Erik L Dahlman, Kevin Z Leder, Susanta K Hui

Theor Biol Med Model· February 2016

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Optimal radiotherapy dose schedules under parametric uncertainty.
Hamidreza Badri, Yoichi Watanabe, Kevin Leder

Phys Med Biol· January 2016

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Minimizing metastatic risk in radiotherapy fractionation schedules.
Hamidreza Badri, Jagdish Ramakrishnan, Kevin Leder

Phys Med Biol· November 2015

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An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer.
Jasmine Foo, Lin L Liu, Kevin Leder, Markus Riester, Yoh Iwasa

PLoS Comput Biol· September 2015

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The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells.
Shannon M Mumenthaler, Jasmine Foo, Nathan C Choi, Nicholas Heise, Kevin Leder

Cancer Inform· August 2015

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Multifocality and recurrence risk: a quantitative model of field cancerization.
Jasmine Foo, Kevin Leder, Marc D Ryser

J Theor Biol· August 2014

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Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules.
Kevin Leder, Ken Pitter, Quincey LaPlant, Dolores Hambardzumyan, Brian D Ross

Cell· January 2014

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