Publications by authors named "Kevin Struhl"

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Distal enhancers loop to proximal enhancers, not to promoters.
Kevin Struhl

Nat Rev Mol Cell Biol· October 2025

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Yeast molecular genetic tricks to study gene regulation.
Kevin Struhl

Genetics· May 2025

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The distinction between epigenetics and epigenomics.
Kevin Struhl

Trends Genet· December 2024

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Location of polyadenylation sites within 3' untranslated regions is linked to biological function in yeast.
Joseph V Geisberg, Zarmik Moqtaderi, Kevin Struhl

Genetics· October 2024

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TRiC/CCT Chaperonin Governs RNA Polymerase II Activity in the Nucleus to Support RNA Homeostasis.
Zlata Gvozdenov, Audrey Yi Tyan Peng, Anusmita Biswas, Zeno Barcutean, Daniel Gestaut, Kevin Struhl

bioRxiv· September 2024

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Non-canonical functions of enhancers: regulation of RNA polymerase III transcription, DNA replication, and V(D)J recombination.
Kevin Struhl

Trends Genet· June 2024

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Chromatin regulates alternative polyadenylation via the RNA polymerase II elongation rate.
Joseph V Geisberg, Zarmik Moqtaderi, Kevin Struhl

Proc Natl Acad Sci U S A· May 2024

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How is polyadenylation restricted to 3'-untranslated regions?
Kevin Struhl

Yeast· April 2024

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Intrinsically disordered regions (IDRs): A vague and confusing concept for protein function.
Kevin Struhl

Mol Cell· April 2024

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Elongation rate of RNA polymerase II affects pausing patterns across 3' UTRs.
Alexandra Khitun, Christian Brion, Zarmik Moqtaderi, Joseph V Geisberg, L Stirling Churchman, Kevin Struhl

J Biol Chem· November 2023

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Functional analysis of a random-sequence chromosome reveals a high level and the molecular nature of transcriptional noise in yeast cells.
Zlata Gvozdenov, Zeno Barcutean, Kevin Struhl

Mol Cell· June 2023

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Condition-specific 3' mRNA isoform half-lives and stability elements in yeast.
Joseph V Geisberg, Zarmik Moqtaderi, Kevin Struhl

Proc Natl Acad Sci U S A· May 2023

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Nucleotide-level linkage of transcriptional elongation and polyadenylation.
Joseph V Geisberg, Zarmik Moqtaderi, Nova Fong, Benjamin Erickson, David L Bentley, Kevin Struhl

Elife· November 2022

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3' Untranslated Regions Are Modular Entities That Determine Polyadenylation Profiles.
Kai Hin Lui, Joseph V Geisberg, Zarmik Moqtaderi, Kevin Struhl

Mol Cell Biol· September 2022

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MafB, WDR77, and ß-catenin interact with each other and have similar genome association profiles.
Lizhi He, Mingshi Gao, Henry Pratt, Zhiping Weng, Kevin Struhl

PLoS One· May 2022

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A compensatory link between cleavage/polyadenylation and mRNA turnover regulates steady-state mRNA levels in yeast.
Zarmik Moqtaderi, Joseph V Geisberg, Kevin Struhl

Proc Natl Acad Sci U S A· January 2022

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Different SP1 binding dynamics at individual genomic loci in human cells.
Yuko Hasegawa, Kevin Struhl

Proc Natl Acad Sci U S A· November 2021

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Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species.
Natalia Petrenko, Kevin Struhl

Elife· September 2021

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YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation.
Lizhi He, Henry Pratt, Mingshi Gao, Fengxiang Wei, Zhiping Weng, Kevin Struhl

Elife· August 2021

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S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation.
Ruisheng Song, Kevin Struhl

Sci Adv· January 2021

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Pheno-RNA, a method to associate genes with a specific phenotype, identifies genes linked to cellular transformation.
Rabih Darwiche, Kevin Struhl

Proc Natl Acad Sci U S A· November 2020

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The transcriptional elongation rate regulates alternative polyadenylation in yeast.
Joseph V Geisberg, Zarmik Moqtaderi, Kevin Struhl

Elife· August 2020

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Promoter-specific dynamics of TATA-binding protein association with the human genome.
Yuko Hasegawa, Kevin Struhl

Genome Res· December 2019

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Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers.
Zhe Ji, Lizhi He, Aviv Regev, Kevin Struhl

Proc Natl Acad Sci U S A· May 2019

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Requirements for RNA polymerase II preinitiation complex formation in vivo.
Natalia Petrenko, Yi Jin, Liguo Dong, Koon Ho Wong, Kevin Struhl

Elife· January 2019

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