Publications by authors named "Kim F Marquart"

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Treatment of a metabolic liver disease in mice with a transient prime editing approach.
Tanja Rothgangl, András Tálas, Eleonora I Ioannidi, Yanik Weber, Desirée Böck, Kim F Marquart

Nat Biomed Eng· October 2025

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Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing.
Nicolas Mathis, Kim Fabiano Marquart, Ahmed Allam, Michael Krauthammer, Gerald Schwank

Nat Protoc· August 2025

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Predicting adenine base editing efficiencies in different cellular contexts by deep learning.
Lucas Kissling, Amina Mollaysa, Sharan Janjuha, Nicolas Mathis, Kim F Marquart

Genome Biol· May 2025

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Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.
Kim Fabiano Marquart, Nicolas Mathis, Amina Mollaysa, Saphira Müller, Lucas Kissling

Nat Methods· November 2024

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Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
Lukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, Tanja Rothgangl, Lucas Kissling

Nat Chem Biol· March 2024

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Enhancing prime editor activity by directed protein evolution in yeast.
Yanik Weber, Desirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Kim F Marquart

Nat Commun· March 2024

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Mutant SF3B1 promotes malignancy in PDAC.
Patrik Simmler, Eleonora I Ioannidi, Tamara Mengis, Kim Fabiano Marquart, Simran Asawa

Elife· October 2023

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Predicting prime editing efficiency and product purity by deep learning.
Nicolas Mathis, Ahmed Allam, Lucas Kissling, Kim Fabiano Marquart, Lukas Schmidheini

Nat Biotechnol· August 2023

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SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer.
Patrik Simmler, Cédric Cortijo, Lisa Maria Koch, Patricia Galliker, Silvia Angori, Kim Fabiano Marquart

Cell Rep· August 2022

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Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing.
Nina Frey, Luigi Tortola, David Egli, Sharan Janjuha, Tanja Rothgangl, Kim Fabiano Marquart

Nat Commun· April 2022

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Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens.
Kim F Marquart, Ahmed Allam, Sharan Janjuha, Anna Sintsova, Lukas Villiger

Nat Commun· August 2021

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Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference.
Kai Xiong, Kim Fabiano Marquart, Karen Julie la Cour Karottki, Shangzhong Li, Isaac Shamie

Biotechnol Bioeng· July 2019

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miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.
Simon Fischer, Kim F Marquart, Lisa A Pieper, Juergen Fieder, Martin Gamer

Biotechnol Bioeng· July 2017

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