Publications by authors named "Nicolas Mathis"

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Spatial profiling of gene editing by in situ sequencing in mice and macaques.
Sharan Janjuha, Tatjana Haenggi, Thomas C Chamberlain, Tanja Rothgangl, Lucas Kissling, Nicolas Mathis

Nat Biomed Eng· September 2025

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Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing.
Nicolas Mathis, Kim Fabiano Marquart, Ahmed Allam, Michael Krauthammer, Gerald Schwank

Nat Protoc· August 2025

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Machine learning prediction of prime editing efficiency across diverse chromatin contexts.
Nicolas Mathis, Ahmed Allam, András Tálas, Lucas Kissling, Elena Benvenuto

Nat Biotechnol· May 2025

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Publisher Correction: Machine learning prediction of prime editing efficiency across diverse chromatin contexts.
Nicolas Mathis, Ahmed Allam, András Tálas, Lucas Kissling, Elena Benvenuto

Nat Biotechnol· May 2025

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Predicting adenine base editing efficiencies in different cellular contexts by deep learning.
Lucas Kissling, Amina Mollaysa, Sharan Janjuha, Nicolas Mathis, Kim F Marquart

Genome Biol· May 2025

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Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.
Kim Fabiano Marquart, Nicolas Mathis, Amina Mollaysa, Saphira Müller, Lucas Kissling

Nat Methods· November 2024

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Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
Lukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, Tanja Rothgangl, Lucas Kissling

Nat Chem Biol· March 2024

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Enhancing prime editor activity by directed protein evolution in yeast.
Yanik Weber, Desirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl

Nat Commun· March 2024

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Predicting prime editing efficiency and product purity by deep learning.
Nicolas Mathis, Ahmed Allam, Lucas Kissling, Kim Fabiano Marquart, Lukas Schmidheini

Nat Biotechnol· August 2023

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Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming.
Kurt Jacobs, Cyril Doerdelmann, Jana Krietsch, Daniel González-Acosta, Nicolas Mathis

Mol Cell· November 2022

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In vivo prime editing of a metabolic liver disease in mice.
Desirée Böck, Tanja Rothgangl, Lukas Villiger, Lukas Schmidheini, Mai Matsushita, Nicolas Mathis

Sci Transl Med· March 2022

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Replacing the Cas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
Lukas Villiger, Lukas Schmidheini, Nicolas Mathis, Tanja Rothgangl, Kim Marquart

Mol Ther Nucleic Acids· December 2021

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A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming.
Michael Cangkrama, Mateusz Wietecha, Nicolas Mathis, Rin Okumura, Luca Ferrarese

EMBO Mol Med· April 2020

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Characterization of two novel intronic OPA1 mutations resulting in aberrant pre-mRNA splicing.
Ramona Bolognini, Christina Gerth-Kahlert, Mathias Abegg, Deborah Bartholdi, Nicolas Mathis

BMC Med Genet· February 2017

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Osteoblast interaction with DLC-coated Si substrates.
Feng Chai, Nicolas Mathis, Nicolas Blanchemain, Cathy Meunier, Hartmut F Hildebrand

Acta Biomater· September 2008

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Ultrastructural features of hepatocytes in cultured Eurasian perch ( Perca fluviatilis L.) as affected by nutritional and husbandry conditions.
Gersande Blanchard, Jean N Gardeur, Nicolas Mathis, Jean Brun-Bellut, Patrick Kestemont

Br J Nutr· August 2008

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