Publications by authors named "Kim Marquart"

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Treatment of a metabolic liver disease in mice with a transient prime editing approach.
Tanja Rothgangl, András Tálas, Eleonora I Ioannidi, Yanik Weber, Desirée Böck, Kim F Marquart

Nat Biomed Eng· October 2025

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Spatial profiling of gene editing by in situ sequencing in mice and macaques.
Sharan Janjuha, Tatjana Haenggi, Thomas C Chamberlain, Tanja Rothgangl, Lucas Kissling, Kim Marquart

Nat Biomed Eng· September 2025

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Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing.
Nicolas Mathis, Kim Fabiano Marquart, Ahmed Allam, Michael Krauthammer, Gerald Schwank

Nat Protoc· August 2025

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Predicting adenine base editing efficiencies in different cellular contexts by deep learning.
Lucas Kissling, Amina Mollaysa, Sharan Janjuha, Nicolas Mathis, Kim F Marquart

Genome Biol· May 2025

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Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.
Kim Fabiano Marquart, Nicolas Mathis, Amina Mollaysa, Saphira Müller, Lucas Kissling

Nat Methods· November 2024

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Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
Lukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, Tanja Rothgangl, Lucas Kissling

Nat Chem Biol· March 2024

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Enhancing prime editor activity by directed protein evolution in yeast.
Yanik Weber, Desirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Kim F Marquart

Nat Commun· March 2024

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Mutant SF3B1 promotes malignancy in PDAC.
Patrik Simmler, Eleonora I Ioannidi, Tamara Mengis, Kim Fabiano Marquart, Simran Asawa

Elife· October 2023

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Predicting prime editing efficiency and product purity by deep learning.
Nicolas Mathis, Ahmed Allam, Lucas Kissling, Kim Fabiano Marquart, Lukas Schmidheini

Nat Biotechnol· August 2023

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SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer.
Patrik Simmler, Cédric Cortijo, Lisa Maria Koch, Patricia Galliker, Silvia Angori, Kim Fabiano Marquart

Cell Rep· August 2022

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Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing.
Nina Frey, Luigi Tortola, David Egli, Sharan Janjuha, Tanja Rothgangl, Kim Fabiano Marquart

Nat Commun· April 2022

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Replacing the Cas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
Lukas Villiger, Lukas Schmidheini, Nicolas Mathis, Tanja Rothgangl, Kim Marquart

Mol Ther Nucleic Acids· December 2021

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Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens.
Kim F Marquart, Ahmed Allam, Sharan Janjuha, Anna Sintsova, Lukas Villiger

Nat Commun· August 2021

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Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference.
Kai Xiong, Kim Fabiano Marquart, Karen Julie la Cour Karottki, Shangzhong Li, Isaac Shamie

Biotechnol Bioeng· July 2019

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miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.
Simon Fischer, Kim F Marquart, Lisa A Pieper, Juergen Fieder, Martin Gamer

Biotechnol Bioeng· July 2017

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Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis.
Michael Kleemann, Jeremias Bereuther, Simon Fischer, Kim Marquart, Simon Hänle

Oncotarget· March 2017

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