Publications by authors named "Kimberley D Bruce"

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Proteomic analysis of cerebrospinal fluid from females with multiple sclerosis highlights elevated microglial function and impaired neurogenesis.
Dean Oldham, Anthony Saviola, Enrique Alvarez, Kimberley D Bruce

IBRO Neurosci Rep· December 2025

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Lipoprotein lipase requires a flexible lid and stable C-terminal, both maintained by ApoC-II peptide binding.
Emma E Lietzke, Mary S Rouse, Dean Oldham, Ziyue Dong, Robert H Eckel, Kimberley D Bruce

bioRxiv· November 2025

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Lipid and lipoprotein metabolism in microglia: Alzheimer's disease mechanisms and interventions.
Kayla G Sprenger, Emma E Lietzke, John T Melchior, Kimberley D Bruce

J Lipid Res· October 2025

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The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids.
David Saeb, Emma E Lietzke, Daisy I Fuchs, Emma C Aldrich, Kimberley D Bruce

Elife· September 2025

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Obesity-Induced MASLD Is Reversed by Capsaicin via Hepatic TRPV1 Activation.
Padmamalini Baskaran, Ryan Christensen, Kimberley D Bruce, Robert H Eckel

Curr Issues Mol Biol· August 2025

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Are CELSR2 Intronic Variants Genetic Determinants of Energy Balance?
Kimberley D Bruce, Robert H Eckel

J Clin Endocrinol Metab· June 2025

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Synergistic reduction in interfacial flexibility of TREM2 and ApoE4 may underlie AD pathology.
Emma E Lietzke, David Saeb, Emma C Aldrich, Kimberley D Bruce, Kayla G Sprenger

Alzheimers Dement· April 2025

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Do microglia metabolize fructose in Alzheimer's disease?
Annalise M Sturno, James E Hassell, Miguel A Lanaspa, Kimberley D Bruce

J Neuroinflammation· March 2025

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GPR182 is a lipoprotein receptor for dietary fat absorption.
Zhiwei Sun, Robert J Torphy, Emily N Miller, Anza Darehshouri, Isaac Vigil, Kimberley D Bruce

bioRxiv· February 2025

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Olfactory and trigeminal routes of HSV-1 CNS infection with regional microglial heterogeneity.
Christy S Niemeyer, Laetitia Merle, Andrew N Bubak, B Dnate' Baxter, Arianna Gentile Polese, Kimberley D Bruce

J Virol· November 2024

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Olfactory and Trigeminal Routes of HSV-1 CNS Infection with Regional Microglial Heterogeneity.
Christy S Niemeyer, Laetitia Merle, Andrew N Bubak, B Dnate' Baxter, Arianna Gentile Polese, Kimberley D Bruce

bioRxiv· September 2024

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Fatty acid sensing in the brain: The role of glial-neuronal metabolic crosstalk and horizontal lipid flux.
Nicholas R W Cleland, Kimberley D Bruce

Biochimie· August 2024

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Suppression of the host antiviral response by non-infectious varicella zoster virus extracellular vesicles.
Christy S Niemeyer, Seth Frietze, Christina Coughlan, Serena W R Lewis, Sara Bustos Lopez, Kimberley D Bruce

J Virol· August 2024

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Altered metabolism and DAM-signatures in female brains and microglia with aging.
Nicholas R W Cleland, Garrett J Potter, Courtney Buck, Daphne Quang, Dean Oldham, Kimberley D Bruce

Brain Res· April 2024

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Can DNA Methylation Predict the Lipid Response to Dietary Intervention? There's a Fat Chance.
Kimberley D Bruce, Robert H Eckel

J Clin Endocrinol Metab· November 2023

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Altered Metabolism and DAM-signatures in Female Brains and Microglia with Aging.
Nicholas R W Cleland, Garrett J Potter, Courtney Buck, Daphne Quang, Dean Oldham, Kimberley D Bruce

bioRxiv· November 2023

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Emerging Alzheimer's disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions.
Nour S Tobeh, Kimberley D Bruce

Front Aging Neurosci· October 2023

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Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health.
Nathaniel J Merrill, W Sean Davidson, Yi He, Ivo Díaz Ludovico, Snigdha Sarkar, Kimberley D Bruce

Sci Adv· September 2023

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Volanesorsen, an antisense oligonucleotide to apolipoprotein C-III, increases lipoprotein lipase activity and lowers triglycerides in partial lipodystrophy.
Marissa Lightbourne, Megan Startzell, Kimberley D Bruce, Brianna Brite, Ranganath Muniyappa

J Clin Lipidol· December 2022

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Using Synthetic ApoC-II Peptides and nAngptl4 Fragments to Measure Lipoprotein Lipase Activity in Radiometric and Fluorescent Assays.
Dean Oldham, Hong Wang, Juliet Mullen, Emma Lietzke, Kayla Sprenger, Kimberley D Bruce

Front Cardiovasc Med· July 2022

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Statins, gut microbiome, LDL-C, glucose intolerance: Personalized medicine timely?
Robert H Eckel, Kimberley D Bruce

Med· June 2022

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Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Kevin A Guttenplan, Maya K Weigel, Priya Prakash, Prageeth R Wijewardhane, Philip Hasel, Kimberley D Bruce

Nature· November 2021

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Altered substrate metabolism in neurodegenerative disease: new insights from metabolic imaging.
Nicholas R W Cleland, Saif I Al-Juboori, Evgenia Dobrinskikh, Kimberley D Bruce

J Neuroinflammation· October 2021

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Editorial: Lipid Metabolism and Transport in CNS Health and Disease.
Kimberley D Bruce, Hussein N Yassine, Alfred N Fonteh

Front Physiol· October 2021

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Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation.
Bailey A Loving, Maoping Tang, Mikaela C Neal, Sachi Gorkhali, Robert Murphy, Kimberley D Bruce

Cells· January 2021

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