Publications by authors named "Kit Cheung"

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Molecular signatures of neuro-HIV and methamphetamine co-morbidity revealed by Raman spectroscopy in postmortem human brain tissue.
Samaneh Ghazanfarpour, Rahul Kumar Das, Kit Wai Cheung, Emma Zabel, Monireh Pourrahimi

Brain Res· January 2026

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Pharmacokinetics, safety and tolerability of ipatasertib in combination with palbociclib and fulvestrant in patients with advanced breast cancer in a phase Ib study.
Kit Wun Kathy Cheung, Ksenia Arzumanova, Victor Poon, Adam Harris, Ryan Johnson

Front Pharmacol· October 2025

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Editorial: Diverse functions of drug transporters.
Jeffry C Granados, Kit Wun Kathy Cheung, Bhagwat Prasad

Front Pharmacol· October 2025

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Association between plasma proteomic dynamic changes and metabolic outcomes in patients undergoing bariatric surgery.
Candela Diaz-Canestro, Wah Yang, Jiarui Chen, Kit Cheung, Hao Han

Int J Obes (Lond)· September 2025

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Maximum likelihood estimation of renal transporter ontogeny profiles for pediatric PBPK modeling.
J Porter Hunt, Samuel Dubinsky, Autumn M McKnite, Kit Wun Kathy Cheung, Bianca D van Groen

CPT Pharmacometrics Syst Pharmacol· April 2024

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Exploring the Impact of Hepatic Impairment on Pralsetinib Pharmacokinetics.
Kit Wun Kathy Cheung, Yang Tang, Doreen Anders, Teresa Barata, Astrid Scalori

Pharmaceutics· April 2024

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Advancing drug development in pediatric oncology, a focus on cancer biology and targeted therapies: iMATRIX platform.
Marianne Uguen, Magalie Hilton, Mufiza Farid-Kapadia, Asim Datye, Saibah Chohan, Kit Wun Kathy Cheung

J Biopharm Stat· November 2023

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Assessment of cytochrome P450 3A4-mediated drug-drug interactions for ipatasertib using a fit-for-purpose physiologically based pharmacokinetic model.
Jing Jing, Yuan Chen, Luna Musib, Jin Y Jin, Kit Wun Kathy Cheung

Cancer Chemother Pharmacol· May 2022

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Population genomics provides insights into the genetic basis of adaptive evolution in the mushroom-forming fungus .
Jingcheng Zhang, Nan Shen, Chuang Li, Xingjie Xiang, Gaolei Liu, Man Kit Cheung

J Adv Res· May 2022

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Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging.
Yuanbing Jiang, Xiaopu Zhou, Fanny C Ip, Philip Chan, Yu Chen, Kit Cheung

Alzheimers Dement· January 2022

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A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice.
Fanny C F Ip, Guangmiao Fu, Fengzhi Yang, Fangyuan Kang, Peiran Sun, Kit Cheung

Eur J Med Chem· December 2021

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Evaluation of Ipatasertib Interactions with Itraconazole and Coproporphyrin I and III in a Single Drug Interaction Study in Healthy Subjects.
Rucha S Sane, Kit Wun Kathy Cheung, Eunpi Cho, Bianca M Liederer, Justin Hanover

J Pharmacol Exp Ther· August 2021

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Effect of Hepatic Impairment on Cobimetinib Pharmacokinetics: The Complex Interplay Between Physiological Changes and Drug Characteristics.
Sravanthi Cheeti, Yuzhong Deng, Ilsung Chang, Isabela Georgescu, Ian Templeton, Kit Wun Kathy Cheung

Clin Pharmacol Drug Dev· February 2021

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Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus.
Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen

Proc Natl Acad Sci U S A· January 2021

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Calibrating the In Vitro-In Vivo Correlation for OATP-Mediated Drug-Drug Interactions with Rosuvastatin Using Static and PBPK Models.
Rucha Sane, Kit Wun Kathy Cheung, Péter Kovács, Taleah Farasyn, Ruina Li

Drug Metab Dispos· December 2020

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A Pentacyclic Triterpene from Targets γ-Secretase.
Wenjie Luo, Fanny C F Ip, Guangmiao Fu, Kit Cheung, Yuan Tian

ACS Chem Neurosci· September 2020

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Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population.
Xiaopu Zhou, Yu Chen, Fanny C F Ip, Nicole C H Lai, Yolanda Y T Li, Kit Cheung

Alzheimers Dement (Amst)· August 2020

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Scientific considerations for global drug development.
Jennifer L Wilson, Kit Wun Kathy Cheung, Lawrence Lin, Elizabeth A E Green, Analia I Porrás

Sci Transl Med· July 2020

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A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization.
Kit Wun Kathy Cheung, Bianca D van Groen, Edwin Spaans, Marjolein D van Borselen, Adrianus C J M de Bruijn

Clin Pharmacol Ther· November 2019

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GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study.
Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley

Drug Metab Dispos· September 2019

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Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters.
Kit Wun Kathy Cheung, Bianca D van Groen, Gilbert J Burckart, Lei Zhang, Saskia N de Wildt

J Clin Pharmacol· September 2019

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Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies.
Sook Wah Yee, Adrian Stecula, Huan-Chieh Chien, Ling Zou, Elena V Feofanova, Kit Wun Kathy Cheung

PLoS Genet· September 2019

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α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis.
Yi-Ting Su, Shun-Fat Lau, Jacque P K Ip, Kit Cheung, Tom H T Cheung

Proc Natl Acad Sci U S A· July 2019

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The Effect of Uremic Solutes on the Organic Cation Transporter 2.
Kit Wun Kathy Cheung, Chia-Hsiang Hsueh, Ping Zhao, Timothy W Meyer, Lei Zhang

J Pharm Sci· September 2017

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NeuroFlow: A General Purpose Spiking Neural Network Simulation Platform using Customizable Processors.
Kit Cheung, Simon R Schultz, Wayne Luk

Front Neurosci· February 2016

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