Publications by authors named "Klarissa D Hardy"

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Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib.
Han Kiat Ho, James Chun Yip Chan, Klarissa D Hardy, Eric Chun Yong Chan

Drug Metab Rev· February 2015

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Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells.
Klarissa D Hardy, Michelle D Wahlin, Ioannis Papageorgiou, Jashvant D Unadkat, Allan E Rettie

Drug Metab Dispos· January 2014

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Isoprostane generation and function.
Ginger L Milne, Huiyong Yin, Klarissa D Hardy, Sean S Davies, L Jackson Roberts

Chem Rev· October 2011

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Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo.
Klarissa D Hardy, Brian E Cox, Ginger L Milne, Huiyong Yin, L Jackson Roberts

J Lipid Res· January 2011

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Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems.
Miroslav Dostalek, Klarissa D Hardy, Ginger L Milne, Jason D Morrow, Chi Chen

J Biol Chem· June 2008

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In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers.
Miroslav Dostalek, Joshua D Brooks, Klarissa D Hardy, Ginger L Milne, Megan M Moore

Mol Pharmacol· December 2007

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