Publications by authors named "Klaus Mauch"

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A guide to gene regulatory network inference for obtaining predictive solutions: Underlying assumptions and fundamental biological and data constraints.
Sara Barbosa, Bastian Niebel, Sebastian Wolf, Klaus Mauch, Ralf Takors

Biosystems· December 2018

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Multiscale modelling approaches for assessing cosmetic ingredients safety.
Frédéric Y Bois, Juan G Diaz Ochoa, Monika Gajewska, Simona Kovarich, Klaus Mauch

Toxicology· December 2017

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A hybrid approach identifies metabolic signatures of high-producers for chinese hamster ovary clone selection and process optimization.
Oliver Popp, Dirk Müller, Katharina Didzus, Wolfgang Paul, Florian Lipsmeier, Klaus Mauch

Biotechnol Bioeng· September 2016

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Metabolic engineering with multi-objective optimization of kinetic models.
Alejandro F Villaverde, Sophia Bongard, Klaus Mauch, Eva Balsa-Canto, Julio R Banga

J Biotechnol· March 2016

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In Silico Modeling for the Prediction of Dose and Pathway-Related Adverse Effects in Humans From In Vitro Repeated-Dose Studies.
Sebastian Klein, Silvia Maggioni, Joachim Bucher, Daniel Mueller, Jens Niklas, Klaus Mauch

Toxicol Sci· January 2016

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Accelerating process development through analysis of cell metabolism.
Dirk Müller, Florian Kirchner, Stefanie Mangin, Klaus Mauch

BMC Proc· April 2015

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A consensus approach for estimating the predictive accuracy of dynamic models in biology.
Alejandro F Villaverde, Sophia Bongard, Klaus Mauch, Dirk Müller, Eva Balsa-Canto

Comput Methods Programs Biomed· April 2015

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BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology.
Alejandro F Villaverde, David Henriques, Kieran Smallbone, Sophia Bongard, Joachim Schmid, Klaus Mauch

BMC Syst Biol· February 2015

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Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models.
Emanuel Gonçalves, Joachim Bucher, Anke Ryll, Jens Niklas, Klaus Mauch

Mol Biosyst· July 2013

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Quantitative Evaluation and Prediction of Drug Effects and Toxicological Risk Using Mechanistic Multiscale Models.
Jens Niklas, Juan G Diaz Ochoa, Joachim Bucher, Klaus Mauch

Mol Inform· January 2013

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A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk.
Juan G Diaz Ochoa, Joachim Bucher, Alexandre R R Péry, José M Zaldivar Comenges, Jens Niklas, Klaus Mauch

Front Pharmacol· January 2013

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Central energy metabolism remains robust in acute steatotic hepatocytes challenged by a high free fatty acid load.
Jens Niklas, Anne Bonin, Stefanie Mangin, Joachim Bucher, Stephanie Kopacz, Klaus Mauch

BMB Rep· July 2012

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Dynamics and control of the central carbon metabolism in hepatoma cells.
Klaus Maier, Ute Hofmann, Matthias Reuss, Klaus Mauch

BMC Syst Biol· April 2010

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Quantification of statin effects on hepatic cholesterol synthesis by transient (13)C-flux analysis.
Klaus Maier, Ute Hofmann, Alexander Bauer, Anja Niebel, Gabriele Vacun, Klaus Mauch

Metab Eng· November 2009

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Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part II. Flux estimation.
Klaus Maier, Ute Hofmann, Matthias Reuss, Klaus Mauch

Biotechnol Bioeng· June 2008

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Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part I. Experimental observations.
Ute Hofmann, Klaus Maier, Anja Niebel, Gabriele Vacun, Matthias Reuss, Klaus Mauch

Biotechnol Bioeng· June 2008

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Metabolic flux analysis in Escherichia coli by integrating isotopic dynamic and isotopic stationary 13C labeling data.
Jochen Schaub, Klaus Mauch, Matthias Reuss

Biotechnol Bioeng· April 2008

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Model of central and trimethylammonium metabolism for optimizing L-carnitine production by E. coli.
Angel Sevilla, Joachim W Schmid, Klaus Mauch, Jose L Iborra, Mathias Reuss

Metab Eng· February 2006

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Metabolic design based on a coupled gene expression-metabolic network model of tryptophan production in Escherichia coli.
Joachim W Schmid, Klaus Mauch, Matthias Reuss, Ernst D Gilles, Andreas Kremling

Metab Eng· October 2004

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Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics.
Diana Visser, Joachim W Schmid, Klaus Mauch, Matthias Reuss, Joseph J Heijnen

Metab Eng· October 2004

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Integration of physiology and fluid dynamics.
Sven Schmalzriedt, Marc Jenne, Klaus Mauch, Matthias Reuss

Adv Biochem Eng Biotechnol· June 2003

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Determination of in vivo kinetics of the starvation-induced Hxt5 glucose transporter of Saccharomyces cerevisiae.
Stefan Buziol, Jessica Becker, Anja Baumeister, Susanne Jung, Klaus Mauch

FEMS Yeast Res· August 2002

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Dynamic modeling of the central carbon metabolism of Escherichia coli.
Christophe Chassagnole, Naruemol Noisommit-Rizzi, Joachim W Schmid, Klaus Mauch, Matthias Reuss

Biotechnol Bioeng· July 2002

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