Publications by authors named "Koen Dechering"

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Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nobutaka Kato, Eamon Comer, Tomoyo Sakata-Kato, Arvind Sharma, Manmohan Sharma, Koen J Dechering

Nature· December 2025

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Killing of Anopheles stephensi mosquitoes by selective triketone inhibitors of 4-hydroxyphenylpyruvate dioxygenase depends on a high protein meal.
Matěj Kučera, David Hartmann, James J Valdés, Adéla Palusová, Avinash Sheshachalam, Koen J Dechering

Insect Biochem Mol Biol· September 2025

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An accessible 3D HepG2/C3A liver spheroid model supporting the complete intrahepatocytic lifecycle of .
Claire H Caygill, Salwa Omar Alqurashi, Adriana Adolfi, Jessica Carson, Angelika Sturm, Koen J Dechering

Parasitology· June 2025

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The mosquitocidal activity of isoxazoline derivatives afoxolaner, lotilaner, and fluralaner are not affected by mosquito sugar or antibiotic treatment.
Harouna Soré, Wamdaogo Moussa Guelbeogo, Soumanaba Zongo, Judith M Bolscher, Nicolas Ouédraogo, Koen J Dechering

Sci Rep· April 2025

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Revisiting the druggable genome using predicted structures and data mining.
Karla P Godinez-Macias, Daisy Chen, J Lincoln Wallis, Miles G Siegel, Anna Adam, Koen J Dechering

NPJ Drug Discov· March 2025

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A deep learning and digital archaeology approach for mosquito repellent discovery.
Jennifer N Wei, Carlos Ruiz, Marnix Vlot, Benjamin Sanchez-Lengeling, Brian K Lee, Koen J Dechering

Chem Senses· January 2025

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Correction: Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.
Noëlie B Henry, Issiaka Soulama, Samuel S Sermé, Judith M Bolscher, Tonnie T G Huijs, Koen J Dechering

PLoS One· December 2024

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Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.
Paula-Josefina Gomez-Gonzalez, Antima Gupta, Laura G Drought, Avnish Patel, John Okombo, Koen J Dechering

Sci Adv· December 2024

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Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining.
Karla P Godinez-Macias, Daisy Chen, J Lincoln Wallis, Miles G Siegel, Anna Adam, Koen J Dechering

Res Sq· November 2024

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A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays.
Yukiko Miyazaki, Martijn W Vos, Fiona J A Geurten, Pierre Bigeard, Hans Kroeze, Koen J Dechering

Commun Biol· July 2023

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Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.
Noëlie B Henry, Issiaka Soulama, Samuel S Sermé, Judith M Bolscher, Tonnie T G Huijs, Koen J Dechering

PLoS One· July 2023

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Metabolic activity organizes olfactory representations.
Wesley W Qian, Jennifer N Wei, Benjamin Sanchez-Lengeling, Brian K Lee, Yunan Luo, Koen Dechering

Elife· May 2023

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Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Amanda Fabra-García, Sophia Hailemariam, Roos M de Jong, Kirsten Janssen, Karina Teelen, Koen J Dechering

Immunity· February 2023

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Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening.
Marie Miglianico, Judith M Bolscher, Martijn W Vos, Karin J M Koolen, Marloes de Bruijni, Koen J Dechering

Commun Biol· February 2023

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Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver.
Blandine Franke-Fayard, Catherin Marin-Mogollon, Fiona J A Geurten, Séverine Chevalley-Maurel, Jai Ramesar, Koen J Dechering

NPJ Vaccines· November 2022

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Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out.
Koen J Dechering, Martijn Timmerman, Kim Rensen, Karin M J Koolen, Saman Honarnejad

SLAS Discov· September 2022

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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Laura E de Vries, Patrick A M Jansen, Catalina Barcelo, Justin Munro, Julie M J Verhoef, Koen J Dechering

Nat Commun· April 2022

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The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity.
Giulia Siciliano, Veronica Di Paolo, Dante Rotili, Rossella Migale, Francesca Pedini, Koen J Dechering

Pharmaceuticals (Basel)· January 2022

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Barcoded Asaia bacteria enable mosquito in vivo screens and identify novel systemic insecticides and inhibitors of malaria transmission.
Angelika Sturm, Martijn W Vos, Rob Henderson, Maarten Eldering, Karin M J Koolen, Koen J Dechering

PLoS Biol· December 2021

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Prioritization of Molecular Targets for Antimalarial Drug Discovery.
Barbara Forte, Sabine Ottilie, Andrew Plater, Brice Campo, Koen J Dechering

ACS Infect Dis· October 2021

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Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.
Benoît Laleu, Yuichiro Akao, Atsuko Ochida, Sandra Duffy, Leonardo Lucantoni, Koen J Dechering

J Med Chem· September 2021

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Generation of a Genetically Modified Chimeric Parasite Expressing Circumsporozoite Protein for Malaria Vaccine Development.
Yukiko Miyazaki, Catherin Marin-Mogollon, Takashi Imai, António M Mendes, Rianne van der Laak, Koen J Dechering

Front Cell Infect Microbiol· June 2021

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MalDA, Accelerating Malaria Drug Discovery.
Tuo Yang, Sabine Ottilie, Eva S Istvan, Karla P Godinez-Macias, Amanda K Lukens, Koen J Dechering

Trends Parasitol· June 2021

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Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Cytoplasmic Prolyl-tRNA Synthetase Inhibitors.
Masanori Okaniwa, Akira Shibata, Atsuko Ochida, Yuichiro Akao, Karen L White, Koen J Dechering

ACS Infect Dis· June 2021

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The circumsporozoite protein produced in is pure and stable.
Susheel K Singh, Jordan Plieskatt, Bishwanath Kumar Chourasia, Vandana Singh, Judith M Bolscher, Koen J Dechering

J Biol Chem· January 2020

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