Publications by authors named "Konstantin Bloch"

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Design, Synthesis, and Characterization of Dichlorobiphenyl-Derived Inhibitors of the Proprotein Convertase Furin.
Roman W Lange, Charlotte Boller, Michael Loresch, Konstantin Bloch, Eva Böttcher-Friebertshäuser

J Med Chem· December 2025

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Structural insights into proprotein convertase activation facilitate the engineering of highly specific furin inhibitors.
Rupert Klaushofer, Konstantin Bloch, Luisa Susanna Eder, Simone Marzaro, Mario Schubert

Nat Commun· September 2025

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Systemic EP4 receptor agonist and Arginase-1 therapy in a murine model of chronic asthma and influenza virus-induced asthma exacerbation.
Tim Lange, Tobias Brunn, Charlotte Vetter, Konstantin Bloch, Nora Vedder

Br J Pharmacol· June 2025

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Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors.
Roman W Lange, Konstantin Bloch, Miriam Ruth Heindl, Jan Wollenhaupt, Manfred S Weiss

ChemMedChem· May 2024

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A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen-specific T cells.
Kathrin Balz, Magali Grange, Uta Pegel, Zain A Karamya, Marielle Mello, Konstantin Bloch

Front Cell Infect Microbiol· January 2024

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Long-term effects of intracranial islet grafting on cognitive functioning in a rat metabolic model of sporadic Alzheimer's disease-like dementia.
Konstantin Bloch, Shay Henry Hornfeld, Shira Dar, Alexey Vanichkin, Irit Gil-Ad

PLoS One· April 2020

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Intracranial Transplantation of Pancreatic Islets Attenuates Cognitive and Peripheral Metabolic Dysfunctions in a Rat Model of Sporadic Alzheimer's Disease.
Konstantin Bloch, Irit Gil-Ad, Alexey Vanichkin, Shay Henry Hornfeld, Michal Taler

J Alzheimers Dis· August 2019

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Trafficking of Grafted Pancreatic Islets Into the Brain Lateral Ventricles: Implications for Cognition.
Konstantin Bloch, Shira Dar, Alexey Vanichkin, Irit Gil-Ad, Pnina Vardi

Transplantation· June 2019

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Intracerebroventricular Streptozotocin Induces Obesity and Dementia in Lewis Rats.
Konstantin Bloch, Irit Gil-Ad, Alexey Vanichkin, Shay Henry Hornfeld, Nickolay Koroukhov

J Alzheimers Dis· May 2018

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Insulin delivery to the brain using intracranial implantation of alginate-encapsulated pancreatic islets.
Konstantin Bloch, Alexey Vanichkin, Irit Gil-Ad, Pnina Vardi, Abraham Weizman

J Tissue Eng Regen Med· November 2017

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Anti-diabetic and neuroprotective effects of pancreatic islet transplantation into the central nervous system.
Daniel Lazard, Pnina Vardi, Konstantin Bloch

Diabetes Metab Res Rev· January 2016

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Intracranial pancreatic islet transplantation increases islet hormone expression in the rat brain and attenuates behavioral dysfunctions induced by MK-801 (dizocilpine).
Konstantin Bloch, Irit Gil-Ad, Igor Tarasenko, Alexey Vanichkin, Michal Taler

Horm Behav· June 2015

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Comment on Gray et al. Insulin regulates brain function, but how does it get there? Diabetes 2014;63:3992-3997.
Konstantin Bloch, Daniel Lazard, Pnina Vardi

Diabetes· June 2015

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Enhanced oxygen supply improves islet viability in a new bioartificial pancreas.
Uriel Barkai, Gordon C Weir, Clark K Colton, Barbara Ludwig, Stefan R Bornstein, Konstantin Bloch

Cell Transplant· April 2014

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Islet transplantation in a subarachnoid cavity surrounding olfactory bulb of diabetic rats.
Konstantin Bloch, Alexey Vanichkin, Pnina Vardi

Transplantation· April 2013

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Induction of beta-cell resistance to hypoxia and technologies for oxygen delivery to transplanted pancreatic islets.
Daniel Lazard, Pnina Vardi, Konstantin Bloch

Diabetes Metab Res Rev· September 2012

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Different susceptibility of rat pancreatic alpha and beta cells to hypoxia.
Konstantin Bloch, Julia Vennäng, Daniel Lazard, Pnina Vardi

Histochem Cell Biol· June 2012

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Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist.
Barbara Ludwig, Avi Rotem, Janine Schmid, Gordon C Weir, Clark K Colton, Konstantin Bloch

Proc Natl Acad Sci U S A· March 2012

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A strategy for the engineering of insulin producing cells with a broad spectrum of defense properties.
Konstantin Bloch, Olga Bloch, Igor Tarasenko, Daniel Lazard, Micha Rapoport

Biomaterials· March 2011

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The novel multifunctional, iron-chelating drugs M30 and HLA20 protect pancreatic beta-cell lines from oxidative stress damage.
Danit Mechlovich, Tamar Amit, Silvia A Mandel, Orit Bar-Am, Konstantin Bloch

J Pharmacol Exp Ther· June 2010

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Catalase expression in pancreatic alpha cells of diabetic and non-diabetic mice.
Konstantin Bloch, Elina Shichman, Marina Vorobeychik, Daria Bloch, Pnina Vardi

Histochem Cell Biol· February 2007

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Immobilized microalgal cells as an oxygen supply system for encapsulated pancreatic islets: a feasibility study.
Konstantin Bloch, Eli Papismedov, Karina Yavriyants, Marina Vorobeychik, Sven Beer

Artif Organs· September 2006

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The relationship between BMI, plasma leptin, insulin and proinsulin before and after laparoscopic adjustable gastric banding.
Edward Ram, Tali Vishne, Rachel Maayan, Igor Lerner, Abraham Weizman, Bloch Konstantin

Obes Surg· April 2006

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Photosynthetic oxygen generator for bioartificial pancreas.
Konstantin Bloch, Eli Papismedov, Karina Yavriyants, Marina Vorobeychik, Sven Beer

Tissue Eng· February 2006

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TH1/TH2 cytokine secretion of first degree relatives of T1DM patients.
Micha J Rapoport, Tzvi Bistritzer, Dorit Aharoni, Mordechai Weiss, Yoram Ramot, Konstantin Bloch

Cytokine· June 2005

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