Publications by authors named "Kousuke Tani"

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Discovery of Novel Seven-Membered Prostacyclin Analogues as Potent and Selective Prostaglandin FP and EP3 Dual Agonists.
Isamu Sugimoto, Tohru Kambe, Tomotaka Okino, Tetsuo Obitsu, Nobukazu Ohta, Kousuke Tani

ACS Med Chem Lett· January 2017

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Structural optimization and structure-functional selectivity relationship studies of G protein-biased EP2 receptor agonists.
Seiji Ogawa, Toshihide Watanabe, Kazumi Moriyuki, Yoshikazu Goto, Shinsaku Yamane, Kousuke Tani

Bioorg Med Chem Lett· May 2016

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Discovery of G Protein-Biased EP2 Receptor Agonists.
Seiji Ogawa, Toshihide Watanabe, Isamu Sugimoto, Kazumi Moriyuki, Yoshikazu Goto, Kousuke Tani

ACS Med Chem Lett· March 2016

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Enantioselective decarboxylative alkylation reactions: catalyst development, substrate scope, and mechanistic studies.
Douglas C Behenna, Justin T Mohr, Nathaniel H Sherden, Smaranda C Marinescu, Andrew M Harned, Kousuke Tani

Chemistry· December 2011

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Discovery of new orally active prostaglandin D2 receptor antagonists.
Maki Iwahashi, Atsushi Naganawa, Atsushi Kinoshita, Atsushi Shimabukuro, Toshihiko Nishiyama, Kousuke Tani

Bioorg Med Chem· November 2011

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A facile and modular synthesis of phosphinooxazoline ligands.
Kousuke Tani, Douglas C Behenna, Ryan M McFadden, Brian M Stoltz

Org Lett· June 2007

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Synthesis of 2-quinuclidonium by eliminating water: experimental quantification of the high basicity of extremely twisted amides.
Tony Ly, Michael Krout, Don K Pham, Kousuke Tani, Brian M Stoltz

J Am Chem Soc· February 2007

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Synthesis and structural analysis of 2-quinuclidonium tetrafluoroborate.
Kousuke Tani, Brian M Stoltz

Nature· June 2006

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Combined effects of prostaglandin E receptor subtype EP1 and subtype EP4 antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice.
Tomohiro Kitamura, Masaki Itoh, Tetsuo Noda, Kousuke Tani, Michiyoshi Kobayashi

Cancer Sci· July 2003

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A practical synthesis and biological evaluation of 9-halogenated PGF analogues.
Kousuke Tani, Atsushi Naganawa, Akiharu Ishida, Hiromu Egashira, Yoshihiko Odagaki

Bioorg Med Chem· June 2002

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Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives.
Kousuke Tani, Atsushi Naganawa, Akiharu Ishida, Kenji Sagawa, Hiroyuki Harada

Bioorg Med Chem· April 2002

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Development of a highly selective EP2-receptor agonist. Part 2: identification of 16-hydroxy-17,17-trimethylene 9beta-chloro PGF derivatives.
Kousuke Tani, Atsushi Naganawa, Akiharu Ishida, Hiromu Egashira, Kenji Sagawa

Bioorg Med Chem· April 2002

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Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.
Michihiro Mutoh, Kouji Watanabe, Tomohiro Kitamura, Yutaka Shoji, Mami Takahashi, Kousuke Tani

Cancer Res· January 2002

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