Publications by authors named "Kristopher Frese"

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Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer.
Alessia Catozzi, Maria Peiris Pagès, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kristopher K Frese

Cell Rep· May 2025

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Functional Characterisation of the ATOH1 Molecular Subtype Indicates a Pro-Metastatic Role in Small Cell Lung Cancer.
Alessia Catozzi, Maria Peiris-Pagès, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kristopher K Frese

bioRxiv· February 2024

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Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry.
Sarah M Pearsall, Stuart C Williamson, Sam Humphrey, Ellyn Hughes, Derrick Morgan, Kristopher K Frese

J Thorac Oncol· October 2023

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cfDNA methylome profiling for detection and subtyping of small cell lung cancers.
Francesca Chemi, Simon P Pearce, Alexandra Clipson, Steven M Hill, Alicia-Marie Conway, Kristopher K Frese

Nat Cancer· October 2022

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Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma.
Melissa Frizziero, Elaine Kilgour, Kathryn L Simpson, Dominic G Rothwell, David A Moore, Kristopher K Frese

Clin Cancer Res· May 2022

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Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer.
Maximilian W Schenk, Sam Humphrey, A S Md Mukarram Hossain, Mitchell Revill, Sarah Pearsall, Kristopher K Frese

Nat Commun· November 2021

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Small cell lung cancer enters the era of precision medicine.
Kristopher K Frese, Kathryn L Simpson, Caroline Dive

Cancer Cell· March 2021

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Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories.
Robert E Hynds, Kristopher K Frese, David R Pearce, Eva Grönroos, Caroline Dive

Open Biol· January 2021

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The Rare YAP1 Subtype of SCLC Revisited in a Biobank of 39 Circulating Tumor Cell Patient Derived Explant Models: A Brief Report.
Sarah M Pearsall, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kristopher K Frese

J Thorac Oncol· December 2020

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Brief report on the clinical characteristics of patients whose samples generate small cell lung cancer circulating tumour cell derived explants.
Alexander J Vickers, Kristopher Frese, Melanie Galvin, Mathew Carter, Lynsey Franklin

Lung Cancer· December 2020

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A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity.
Kathryn L Simpson, Ruth Stoney, Kristopher K Frese, Nicole Simms, William Rowe

Nat Cancer· April 2020

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Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer.
Mariano Ponz-Sarvise, Vincenzo Corbo, Hervé Tiriac, Dannielle D Engle, Kristopher K Frese

Clin Cancer Res· November 2019

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Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics.
Alice Lallo, Sakshi Gulati, Maximilian W Schenk, Garima Khandelwal, Ulrika Warpman Berglund, Kristopher K Frese

Br J Pharmacol· February 2019

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The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer.
Alice Lallo, Kristopher K Frese, Christopher J Morrow, Robert Sloane, Sakshi Gulati

Clin Cancer Res· October 2018

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Will liquid biopsies improve outcomes for patients with small-cell lung cancer?
Fiona Blackhall, Kristopher K Frese, Kathryn Simpson, Elaine Kilgour, Ged Brady

Lancet Oncol· September 2018

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Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin.
Pedro Torres-Ayuso, Sudhakar Sahoo, Garry Ashton, Elvira An, Nicole Simms, Kristopher K Frese

NPJ Genom Med· June 2018

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Targeting DNA damage in SCLC.
Victoria Foy, Maximilian W Schenk, Katie Baker, Fabio Gomes, Alice Lallo, Kristopher K Frese

Lung Cancer· December 2017

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PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.
Terrence F Meehan, Nathalie Conte, Theodore Goldstein, Giorgio Inghirami, Mark A Murakami, Kristopher K Frese

Cancer Res· November 2017

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PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways.
Srivatsava Naidu, Lei Shi, Peter Magee, Justin D Middleton, Alessandro Laganá, Kristopher Frese

Sci Rep· November 2017

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Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models.
Garima Khandelwal, María Romina Girotti, Christopher Smowton, Sam Taylor, Christopher Wirth, Kristopher K Frese

Mol Cancer Res· August 2017

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Circulating tumor cells and CDX models as a tool for preclinical drug development.
Alice Lallo, Maximilian W Schenk, Kristopher K Frese, Fiona Blackhall, Caroline Dive

Transl Lung Cancer Res· August 2017

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MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model.
Eva M Serrao, Mikko I Kettunen, Tiago B Rodrigues, Piotr Dzien, Alan J Wright, Kristopher K Frese

Gut· March 2016

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PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways.
Brajesh P Kaistha, Holger Lorenz, Harald Schmidt, Bence Sipos, Michael Pawlak, Kristopher K Frese

Cancer Res· January 2016

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RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells.
Ningfeng Fiona Li, Emilios Gemenetzidis, Francis J Marshall, Derek Davies, Yongwei Yu, Kristopher Frese

PLoS One· September 2014

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SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice.
Albrecht Neesse, Kristopher K Frese, Derek S Chan, Tashinga E Bapiro, William J Howat

Gut· June 2014

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