Publications by authors named "Kristopher King"

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Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation .
J Howard Jones, Zhili Xin, Martin Himmelbauer, Michael Dechantsreiter, Istvan Enyedy, Kristopher W King

J Med Chem· October 2021

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Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.
Tamara Halkina, Jaclyn L Henderson, Edward Y Lin, Martin K Himmelbauer, J Howard Jones, Kristopher King

J Med Chem· May 2021

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Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites.
Gregory M Dillon, Jaclyn L Henderson, Channa Bao, John A Joyce, Michael Calhoun, Kristopher W King

PLoS One· July 2020

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Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors.
Zhili Xin, Martin K Himmelbauer, J Howard Jones, Istvan Enyedy, Rab Gilfillan, Kristopher King

ACS Med Chem Lett· April 2020

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Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors.
Martin K Himmelbauer, Zhili Xin, J Howard Jones, Istvan Enyedy, Kristopher King

J Med Chem· December 2019

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Well-developed ligand-binding assays demonstrate robust performance using singlet analysis.
Douglas Donaldson, Shobha Purushothama, Eric David, Kristopher King, Shuguang Huang

Bioanalysis· November 2019

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Online and automated sample extraction.
Dong Wei, Ming Li, Kristopher W King, Liyu Yang

Bioanalysis· July 2016

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Small-molecule bioanalytical sample preparation method development starting from the BASICS.
Ming Li, Judy Chou, Kristopher W King, Liyu Yang

Bioanalysis· September 2015

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ICECAP: an integrated, general-purpose, automation-assisted IC50/EC50 assay platform.
Ming Li, Judy Chou, Kristopher W King, Jing Jing, Dong Wei

J Lab Autom· February 2015

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ASPECTS: an automation-assisted SPE method development system.
Ming Li, Judy Chou, Kristopher W King, Liyu Yang

Bioanalysis· July 2013

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