Publications by authors named "Kumiko Takeuchi"

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Perspective of the Pharmaceuticals and Medical Devices Agency on Drug Development for Childhood Myopia.
Mitsuru Arima, Motomasa Atsumi, Kumiko Takeuchi, Takumi Aoki, Emi Inagaki

Clin Pharmacol Ther· January 2026

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CHAC1 exacerbates arsenite cytotoxicity by lowering intracellular glutathione levels.
Daigo Sumi, Hiroki Taguchi, Kumiko Takeuchi, Hitomi Fujishiro

J Toxicol Sci· September 2023

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Long-lasting inhibitory effects of saquinavir and ritonavir on OATP1B1-mediated uptake.
Yoshihisa Shitara, Kumiko Takeuchi, Toshiharu Horie

J Pharm Sci· September 2013

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Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.
Yoshihisa Shitara, Kumiko Takeuchi, Yoshiko Nagamatsu, Satomi Wada, Yuichi Sugiyama

Drug Metab Pharmacokinet· June 2013

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Structure activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 2.
Kumiko Takeuchi, William G Holloway, Charles H Mitch, Steven J Quimby, Jamie H McKinzie

Bioorg Med Chem Lett· December 2007

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Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.
Kumiko Takeuchi, William G Holloway, Jamie H McKinzie, Todd M Suter, Michael A Statnick

Bioorg Med Chem Lett· October 2007

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A toxicogenomic approach revealed hepatic gene expression changes mechanistically linked to drug-induced hemolytic anemia.
Masatomo Rokushima, Kazuo Omi, Akiko Araki, Yoshimasa Kyokawa, Naoko Furukawa, Kumiko Takeuchi

Toxicol Sci· February 2007

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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 5.
Kumiko Takeuchi, Todd J Kohn, Nicholas A Honigschmidt, Vincent P Rocco, Patrick G Spinazze

Bioorg Med Chem Lett· May 2006

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Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins.
Kentaro Tsukamoto, Tomoko Kohda, Masafumi Mukamoto, Kumiko Takeuchi, Hideshi Ihara

J Biol Chem· October 2005

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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 4.
Vincent P Rocco, Patrick G Spinazze, Todd J Kohn, Nicholas A Honigschmidt, David L Nelson, Kumiko Takeuchi

Bioorg Med Chem Lett· May 2004

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DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner.
Wenxiang Meng, Mitsuko Numazaki, Kumiko Takeuchi, Yoshiari Uchibori, Yuhko Ando-Akatsuka

EMBO J· February 2004

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Fission yeast epsin, Ent1p is required for endocytosis and involved in actin organization.
Chika Sakamoto, Chitose Kawamoto, Kumiko Takeuchi, Ikumi Miyamoto, Hisato Shuntoh

Kobe J Med Sci· January 2004

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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3.
Kumiko Takeuchi, Todd J Kohn, Nicholas A Honigschmidt, Vincent P Rocco, Patrick G Spinazze

Bioorg Med Chem Lett· November 2003

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Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2.
Kumiko Takeuchi, Todd J Kohn, Nicholas A Honigschmidt, Vincent P Rocco, Patrick G Spinazze

Bioorg Med Chem Lett· July 2003

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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1.
Kumiko Takeuchi, Todd J Kohn, Nicholas A Honigschmidt, Vincent P Rocco, Patrick G Spinazze

Bioorg Med Chem Lett· June 2003

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Structural determinant of TRPV1 desensitization interacts with calmodulin.
Mitsuko Numazaki, Tomoko Tominaga, Kumiko Takeuchi, Namie Murayama, Hidenori Toyooka

Proc Natl Acad Sci U S A· June 2003

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