Publications by authors named "Kwame Nti-Addae"

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Adaptive Focused Acoustics™ for Nanosuspensions to Enable Pharmacology Assessment of Poorly Soluble Molecules in Lead Optimization.
Kathy Stavropoulos, Jim Bernhard, Kwame Nti-Addae, Elisabeth Doyle, Wojciech Dworakowski

J Pharm Sci· July 2021

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Discovery of Novel, Orally Bioavailable β-Amino Acid Azaindole Inhibitors of Influenza PB2.
Luc J Farmer, Michael P Clark, Michael J Boyd, Emanuele Perola, Steven M Jones, Kwame Nti-Addae

ACS Med Chem Lett· February 2017

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Novel 2-Substituted 7-Azaindole and 7-Azaindazole Analogues as Potential Antiviral Agents for the Treatment of Influenza.
Upul K Bandarage, Michael P Clark, Emanuele Perola, Huai Gao, Marc D Jacobs

ACS Med Chem Lett· February 2017

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Novel Ranking System for Identifying Efficacious Anti-Influenza Virus PB2 Inhibitors.
Alice W Tsai, Colleen F McNeil, Joshua R Leeman, Hamilton B Bennett, Kwame Nti-Addae

Antimicrob Agents Chemother· October 2015

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Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2.
Michael P Clark, Mark W Ledeboer, Ioana Davies, Randal A Byrn, Steven M Jones, Kwame Nti-Addae

J Med Chem· August 2014

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Determination of the permeability characteristics of two sulfenamide prodrugs of linezolid across Caco-2 cells.
Kwame W Nti-Addae, Victor R Guarino, Gautam Dalwadi, Valentino J Stella

J Pharm Sci· September 2012

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Reversion of sulfenamide prodrugs in the presence of free thiol-containing proteins.
Kwame W Nti-Addae, Jennifer S Laurence, Andria L Skinner, Valentino J Stella

J Pharm Sci· July 2011

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Reprint of "MDCK cell permeability characteristics of a sulfenamide produg: strategic implications in considering sulfenamide prodrugs for oral delivery of NH acids" [Bioorg. Med. Chem. Lett. 21 (2011) 172-175].
Victor R Guarino, Kwame Nti-Addae, Valentino J Stella

Bioorg Med Chem Lett· May 2011

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In vitro conversion of model sulfenamide prodrugs in the presence of small molecule thiols.
Kwame W Nti-Addae, Valentino J Stella

J Pharm Sci· March 2011

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MDCK cell permeability characteristics of a sulfenamide prodrug: strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acids.
Victor R Guarino, Kwame Nti-Addae, Valentino J Stella

Bioorg Med Chem Lett· January 2011

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Preparation, characterization and in vivo conversion of new water-soluble sulfenamide prodrugs of carbamazepine.
Jeffrey N Hemenway, Kwame Nti-Addae, Victor R Guarino, Valentino J Stella

Bioorg Med Chem Lett· December 2007

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Prodrug strategies to overcome poor water solubility.
Valentino J Stella, Kwame W Nti-Addae

Adv Drug Deliv Rev· July 2007

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