Publications by authors named "Kwan Cheng"

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Exploring Tau Fibril-Disaggregating and Antioxidating Molecules Binding to Membrane-Bound Amyloid Oligomers Using Machine Learning-Enhanced Docking and Molecular Dynamics.
Luthary Segura, Natalia Santos, Rafael Flores, Donald Sikazwe, Miles McGibbon, Kwan H Cheng

Molecules· June 2024

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Multiscale Modeling of Macromolecular Interactions between Tau-Amylin Oligomers and Asymmetric Lipid Nanodomains That Link Alzheimer's and Diabetic Diseases.
Natalia Santos, Luthary Segura, Amber Lewis, Thuong Pham, Kwan H Cheng

Molecules· February 2024

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Testosterone Pellet Use in Transgender Men.
Kwan Cheng, Aren Skolnick

Transgend Health· December 2023

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Lipid domain boundary triggers membrane damage and protein folding of human islet amyloid polypeptide in the early pathogenesis of amyloid diseases.
Amber Lewis, Thuong Pham, Ngoc Nguyen, Angela Graf, Kwan H Cheng

Biophys Chem· May 2023

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Exploring the Role of Anionic Lipid Nanodomains in the Membrane Disruption and Protein Folding of Human Islet Amyloid Polypeptide Oligomers on Lipid Membrane Surfaces Using Multiscale Molecular Dynamics Simulations.
Ngoc Nguyen, Amber Lewis, Thuong Pham, Donald Sikazwe, Kwan H Cheng

Molecules· May 2023

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Design and Synthesis of New Acyl Urea Analogs as Potential σ1R Ligands.
Rajesh Thapa, Rafael Flores, Kwan H Cheng, Bereket Mochona, Donald Sikazwe

Molecules· March 2023

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Exploring the binding kinetics and behaviors of self-aggregated beta-amyloid oligomers to phase-separated lipid rafts with or without ganglioside-clusters.
Thuong Pham, Kwan H Cheng

Biophys Chem· November 2022

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Exploring Membrane Binding Targets of Disordered Human Tau Aggregates on Lipid Rafts Using Multiscale Molecular Dynamics Simulations.
Kwan H Cheng, Angela Graf, Amber Lewis, Thuong Pham, Aakriti Acharya

Membranes (Basel)· November 2022

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Suspected Primary Adrenal Lymphoma (PAL) Associated With Hemophagocytic Lymphohistiocytosis (HLH).
Tara S Kim, Kwan Cheng, Radhika Jaiswal, Pranisha Gautam-Goyal, Alyson K Myers

J Endocr Soc· January 2021

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Data showing the lipid conformations and membrane binding behaviors of beta-amyloid fibrils in phase-separated cholesterol-enriched lipid domains with and without glycolipid and oxidized cholesterol from coarse-grained molecular dynamics simulations.
Sara Y Cheng, Yiyi Cao, Marzieh Rouzbehani, Kwan H Cheng

Data Brief· June 2020

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Coarse-grained MD simulations reveal beta-amyloid fibrils of various sizes bind to interfacial liquid-ordered and liquid-disordered regions in phase separated lipid rafts with diverse membrane-bound conformational states.
Sara Y Cheng, Yiyi Cao, Marzieh Rouzbehani, Kwan H Cheng

Biophys Chem· May 2020

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Effects of Cholesterol in Stress-Related Neuronal Death-A Statistical Analysis Perspective.
Maher A Dayeh, George Livadiotis, Farzan Aminian, Kwan H Cheng, James L Roberts

Int J Mol Sci· April 2020

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Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient.
Lubna Bashir Munshi, Yumiko Tsushima, Kwan Cheng, Maria Brito

Case Rep Endocrinol· July 2018

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Dynamic Fingering in Adhered Lipid Membranes.
Orrin Shindell, Natalie Mica, Kwan H Cheng, Exing Wang, Vernita D Gordon

Langmuir· April 2018

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4,5-Dimethoxy-2-nitrobenzohydrazides and 1-(1-Benzylpiperidin-4-yl)ethan-1-ones as Potential Antioxidant/Cholinergic Endowed Small Molecule Leads.
Rukhsar Banu, Jason Gerding, Cynthia Franklin, Donald Sikazwe, William Horton, Kwan H Cheng

Sci Pharm· December 2017

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Data supporting beta-amyloid dimer structural transitions and protein-lipid interactions on asymmetric lipid bilayer surfaces using MD simulations on experimentally derived NMR protein structures.
Sara Y Cheng, George Chou, Creighton Buie, Mark W Vaughn, Campbell Compton, Kwan H Cheng

Data Brief· June 2016

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Maximally asymmetric transbilayer distribution of anionic lipids alters the structure and interaction with lipids of an amyloidogenic protein dimer bound to the membrane surface.
Sara Y Cheng, George Chou, Creighton Buie, Mark W Vaughn, Campbell Compton, Kwan H Cheng

Chem Phys Lipids· March 2016

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Lipid insertion domain unfolding regulates protein orientational transition behavior in a lipid bilayer.
Kwan Hon Cheng, Liming Qiu, Sara Y Cheng, Mark W Vaughn

Biophys Chem· November 2015

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Characterization of 3D Voronoi tessellation nearest neighbor lipid shells provides atomistic lipid disruption profile of protein containing lipid membranes.
Sara Y Cheng, Hai V Duong, Campbell Compton, Mark W Vaughn, Hoa Nguyen, Kwan H Cheng

Biophys Chem· March 2015

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Scaling and alpha-helix regulation of protein relaxation in a lipid bilayer.
Liming Qiu, Creighton Buie, Kwan Hon Cheng, Mark W Vaughn

J Chem Phys· December 2014

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Calorimetric behavior of phosphatidylcholine/phosphatidylethanolamine bilayers is compatible with the superlattice model.
Kwan Hon Cheng, Jorma Virtanen, Pentti Somerharju

J Phys Chem B· February 2012

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Molecular dynamics simulations reveal the protective role of cholesterol in β-amyloid protein-induced membrane disruptions in neuronal membrane mimics.
Liming Qiu, Creighton Buie, Andrew Reay, Mark W Vaughn, Kwan Hon Cheng

J Phys Chem B· August 2011

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Acyl-chain mismatch driven superlattice arrangements in DPPC/DLPC/cholesterol bilayers.
Brian Cannon, Anthony Lewis, Pentti Somerharju, Jorma Virtanen, Juyang Huang, Kwan Hon Cheng

J Phys Chem B· August 2010

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Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers.
Liming Qiu, Anthony Lewis, John Como, Mark W Vaughn, Juyang Huang, Kwan Hon Cheng

Biophys J· May 2009

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Effect of quinone on the fluorescence decay dynamics of endogenous flavin bound to bacterial luciferase.
Elena V Vetrova, Nadezhda S Kudryasheva, Kwan H Cheng

Biophys Chem· April 2009

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