Publications by authors named "Kyeonghwan Kim"

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Clearance of amyloid plaque via focused ultrasonication in a mouse model of Alzheimer's disease.
Songmin Lee, Jeungeun Kum, Kyeonghwan Kim, Tae Young Park, HeeEun Ko, Hyungmin Kim, YoungSoo Kim, Jaeho Kim

Theranostics· December 2025

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Drug Discovery and Screening Tool Development for Tauopathies by Focusing on Pathogenic Tau Repeat 3 Oligomers.
Soljee Yoon, Hye Yun Kim, Sohui Park, Minhae Cha, Kyeonghwan Kim, JiMin Kim, YoungSoo Kim

Angew Chem Int Ed Engl· December 2024

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Modulation of Amyloid and Tau Aggregation to Alleviate Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease.
Sohui Park, Jisu Shin, Kyeonghwan Kim, Darong Kim, Won Seok Lee, Hye Yun Kim, YoungSoo Kim

ACS Pharmacol Transl Sci· September 2024

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Early onset diagnosis in Alzheimer's disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid.
Jusung An, Kyeonghwan Kim, Ho Jae Lim, Hye Yun Kim, Jinwoo Shin, Hyeong Yun Kim, Sunghoon Kim, YoungSoo Kim, Jong Seung Kim

Nat Commun· February 2024

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Benzo[]imidazole-pyrrolo[1,2-]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice.
Minhae Cha, Anuradha Dagar, Sunhee Lee, Illhwan Cho, Donghee Lee, Kyeonghwan Kim, Hye Yun Kim, Ikyon Kim, YoungSoo Kim

ACS Chem Neurosci· September 2023

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4-Acyl-3,4-dihydropyrrolo[1,2-]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates.
Songmin Lee, Anuradha Dagar, Illhwan Cho, Kyeonghwan Kim, In Wook Park, Hye Yun Kim, Ikyon Kim, YoungSoo Kim

ACS Chem Neurosci· June 2023

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Amyloid Against Amyloid: Dimeric Amyloid Fragment Ameliorates Cognitive Impairments by Direct Clearance of Oligomers and Plaques.
Hee Yang Lee, Seungyeop Baek, Minhae Cha, Seung-Hoon Yang, Illhwan Cho, Hye Yun Kim, Kyeonghwan Kim, Jiyoon Kim, Seong Muk Kim, Ko Eun Kim, Hye Ju Kim, YoungSoo Kim

Angew Chem Int Ed Engl· February 2023

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Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models.
Hee Yang Lee, Soljee Yoon, Jeong Hwa Lee, Keunwan Park, Youngeun Jung, Kyeonghwan Kim, Sunmi Kim, Jimin Kim, Koeun Kim, Seong Muk Kim, Hye Ju Kim, Hye Yun Kim, Ikyon Kim, Young Soo Kim

Alzheimers Res Ther· November 2022

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Engineered Surface Halide Defects by Two-Dimensional Perovskite Passivation for Deformable Intelligent Photodetectors.
Taehee Kim, Seongsik Jeong, Kyeong-Hwan Kim, Hyunseok Shim, Dongho Kim, Hae-Jin Kim

ACS Appl Mater Interfaces· June 2022

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Anti-amyloidogenic indolizino[3,2-]quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β.
Kyeonghwan Kim, Jeong Hwa Lee, Sunmi Kim, Songmin Lee, Donghee Lee, Hye Yun Kim, Ikyon Kim, YoungSoo Kim

RSC Med Chem· November 2021

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Correction: Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model.
DaWon Kim, Jeong Hwa Lee, Hye Yun Kim, Jisu Shin, Kyeonghwan Kim, Ikyon Kim, YoungSoo Kim

PLoS One· April 2021

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Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse.
DaWon Kim, Gi Hun Bae, Hye Yun Kim, Hanna Jeon, Kyeonghwan Kim, Ikyon Kim, YoungSoo Kim

ACS Chem Neurosci· January 2021

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Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model.
DaWon Kim, Jeong Hwa Lee, Hye Yun Kim, Jisu Shin, Kyeonghwan Kim, JinIkyon Kim, YoungSoo Kim

PLoS One· January 2021

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Rhizolutin, a Novel 7/10/6-Tricyclic Dilactone, Dissociates Misfolded Protein Aggregates and Reduces Apoptosis/Inflammation Associated with Alzheimer's Disease.
Yun Kwon, Jisu Shin, Kwangho Nam, Joon Soo An, Seung-Hoon Yang, Kyeonghwan Kim, Byung-Yong Kim, YoungSoo Kim

Angew Chem Int Ed Engl· December 2020

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Discovery of Chemicals to Either Clear or Indicate Amyloid Aggregates by Targeting Memory-Impairing Anti-Parallel Aβ Dimers.
Jinny Claire Lee, Hye Yun Kim, Sejin Lee, Jisu Shin, Hyunjin Vincent Kim, Kyeonghwan Kim, DaWon Kim, Kim D Janda, YoungSoo Kim

Angew Chem Int Ed Engl· July 2020

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Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease.
Da Eun Kwak, Taeho Ko, Han Seok Koh, Yong Woo Ji, Jisu Shin, Kyeonghwan Kim, Hye Yun Kim, YoungSoo Kim

PLoS One· April 2020

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Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system.
YoungSoo Kim, Yong Kyoung Yoo, Hye Yun Kim, Jee Hoon Roh, Jinsik Kim, Hye Jin Kim, Kyeonghwan Kim, Jae-Seung Kim

Sci Adv· April 2019

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A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice.
Seung-Hoon Yang, Jisu Shin, Naewoo Neo Shin, Ji-Hyun Hwang, Sung-Chul Hong, Kyeonghwan Kim, YoungSoo Kim

Sci Rep· March 2019

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