Publications by authors named "Lakshay Malhotra"

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Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-4.
Ravi Chauhan, Gunjan Dagar, Lakshay Malhotra, Ashna Gupta, Anju Surendranath

J Transl Med· December 2025

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Biophysical and molecular characterization of HuR inhibitors, CMLD-2 and Dihydrotanshinone I (DHTS), in Triple Negative Breast Cancer (TNBC).
Arundhathi J R Dev, Lakshay Malhotra, Akanksha Kashyap, Sheikh Mohammad Umar, Meetu Rathee

Int J Biol Macromol· August 2025

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The R337C mutation in the p53 oligomerization domain affects the regulatory domain and its ability to bind response elements: Evidence based on structural and biophysical studies.
Alankrita Singh, Lakshay Malhotra, Abhay Mishra, Simran Kundral, Pawan Kumar Tiwari

Arch Biochem Biophys· June 2025

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Unraveling the unique amyloid-like aggregation behavior of the tumor suppressor p53 mutants in human cancers.
Nisha Manav, Pratibha Sharma, Sankat Mochan, Lakshay Malhotra

Int J Biol Macromol· June 2025

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Comprehensive amino acid composition analysis of seed storage proteins of cereals and legumes: identification and understanding of intrinsically disordered and allergenic peptides.
Pratibha Sharma, Lakshay Malhotra, Rajinder K Dhamija

J Biomol Struct Dyn· April 2025

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Phenotypical mapping of TP53 unique missense mutations spectrum in human cancers.
Lakshay Malhotra, Alankrita Singh, Punit Kaur, Abdul S Ethayathulla

J Biomol Struct Dyn· December 2024

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Flavonoids as potential reactivators of structural mutation p53Y220C by computational and cell-based studies.
Lakshay Malhotra, Punit Kaur, Abdul Samath Ethayathulla

J Biomol Struct Dyn· November 2024

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Bergenin inhibits growth of human cervical cancer cells by decreasing Galectin-3 and MMP-9 expression.
Ravi Chauhan, Lakshay Malhotra, Ashna Gupta, Gunjan Dagar, Mohini Mendiratta

Sci Rep· July 2024

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Comprehensive omics studies of p53 mutants in human cancer.
Lakshay Malhotra, Alankrita Singh, Punit Kaur, Abdul S Ethayathulla

Brief Funct Genomics· April 2023

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Putative interactions between transthyretin and endosulfan II and its relevance in breast cancer.
Saurabh Sharma, Lakshay Malhotra, Paromita Mukherjee, Navneet Kaur, Thammineni Krishanlata

Int J Biol Macromol· April 2023

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Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression.
Ravi Chauhan, Ashna Gupta, Lakshay Malhotra, Ajaz A Bhat, Raj K Pandita

J Transl Med· April 2023

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Mechanism of apoptosis activation by Curcumin rescued mutant p53Y220C in human pancreatic cancer.
Lakshay Malhotra, Saurabh Sharma, Gururao Hariprasad, Renu Dhingra, Vandana Mishra

Biochim Biophys Acta Mol Cell Res· December 2022

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Heteroarene-fused anthraquinone derivatives as potential modulators for human aurora kinase B.
Mandeep Singh, Lakshay Malhotra, Md Anzarul Haque, Mukesh Kumar, Alexander Tikhomirov

Biochimie· March 2021

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Curcumin rescue p53Y220C in BxPC-3 pancreatic adenocarcinomas cell line: Evidence-based on computational, biophysical, and in vivo studies.
Lakshay Malhotra, Harsh K V Goyal, Sunita Jhuria, Kapil Dev, Saroj Kumar

Biochim Biophys Acta Gen Subj· February 2021

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