Publications by authors named "Lalit Deshmukh"

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Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Using Chemical Exchange NMR.
Brianna N Kalaj, James J La Clair, Yang Shen, Charles D Schwieters, Lalit Deshmukh

J Am Chem Soc· July 2024

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Phase Separation and Fibrillization of Human Annexin A7 Are Mediated by Its Proline-Rich Domain.
Chenrong Yu, Spencer L Nelson, Georg Meisl, Rodolfo Ghirlando, Lalit Deshmukh

Biochemistry· November 2023

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ALS Variants of Annexin A11's Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution.
Aman Shihora, Ruben D Elias, John A Hammond, Rodolfo Ghirlando, Lalit Deshmukh

ACS Chem Neurosci· August 2023

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Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation.
Ruben D Elias, Yingqi Zhu, Qi Su, Rodolfo Ghirlando, Jin Zhang, Lalit Deshmukh

Sci Adv· July 2023

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Avidity-Based Method for the Efficient Generation of Monoubiquitinated Recombinant Proteins.
Spencer L Nelson, Yunan Li, Yue Chen, Lalit Deshmukh

J Am Chem Soc· April 2023

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Mechanistic roles of tyrosine phosphorylation in reversible amyloids, autoinhibition, and endosomal membrane association of ALIX.
Ruben D Elias, Bhargavi Ramaraju, Lalit Deshmukh

J Biol Chem· November 2021

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Quantitative NMR Study of Insulin-Degrading Enzyme Using Amyloid-β and HIV-1 p6 Elucidates Its Chaperone Activity.
Bhargavi Ramaraju, Spencer L Nelson, Wenwei Zheng, Rodolfo Ghirlando, Lalit Deshmukh

Biochemistry· August 2021

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Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids.
Ruben D Elias, Wen Ma, Rodolfo Ghirlando, Charles D Schwieters, Vijay S Reddy, Lalit Deshmukh

Proc Natl Acad Sci U S A· September 2020

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Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator.
Lisa M Miller Jenkins, Elliott L Paine, Lalit Deshmukh, Herman Nikolayevskiy, Gaelyn C Lyons

J Am Chem Soc· May 2019

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Targeting a Dark Excited State of HIV-1 Nucleocapsid by Antiretroviral Thioesters Revealed by NMR Spectroscopy.
Lalit Deshmukh, Vitali Tugarinov, Daniel H Appella, G Marius Clore

Angew Chem Int Ed Engl· March 2018

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Binding kinetics and substrate selectivity in HIV-1 protease-Gag interactions probed at atomic resolution by chemical exchange NMR.
Lalit Deshmukh, Vitali Tugarinov, John M Louis, G Marius Clore

Proc Natl Acad Sci U S A· November 2017

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Transient HIV-1 Gag-protease interactions revealed by paramagnetic NMR suggest origins of compensatory drug resistance mutations.
Lalit Deshmukh, John M Louis, Rodolfo Ghirlando, G Marius Clore

Proc Natl Acad Sci U S A· November 2016

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Quantitative Characterization of Configurational Space Sampled by HIV-1 Nucleocapsid Using Solution NMR, X-ray Scattering and Protein Engineering.
Lalit Deshmukh, Charles D Schwieters, Alexander Grishaev, G Marius Clore

Chemphyschem· June 2016

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Mutations Proximal to Sites of Autoproteolysis and the α-Helix That Co-evolve under Drug Pressure Modulate the Autoprocessing and Vitality of HIV-1 Protease.
John M Louis, Lalit Deshmukh, Jane M Sayer, Annie Aniana, G Marius Clore

Biochemistry· September 2015

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Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy.
Lalit Deshmukh, Rodolfo Ghirlando, G Marius Clore

Proc Natl Acad Sci U S A· March 2015

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Skelemin association with αIIbβ3 integrin: a structural model.
Vitaliy Gorbatyuk, Khiem Nguyen, Nataly P Podolnikova, Lalit Deshmukh, Xiaochen Lin

Biochemistry· November 2014

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Investigation of the structure and dynamics of the capsid-spacer peptide 1-nucleocapsid fragment of the HIV-1 gag polyprotein by solution NMR spectroscopy.
Lalit Deshmukh, Rodolfo Ghirlando, G Marius Clore

Angew Chem Int Ed Engl· January 2014

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Structure and dynamics of full-length HIV-1 capsid protein in solution.
Lalit Deshmukh, Charles D Schwieters, Alexander Grishaev, Rodolfo Ghirlando, James L Baber

J Am Chem Soc· October 2013

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Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch.
Xiaoxia Z West, Nahum Meller, Nikolay L Malinin, Lalit Deshmukh, Julia Meller

PLoS One· June 2012

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Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: the stabilizing effect of membrane-mimetics on the acquired fold.
Paolo De Bona, Lalit Deshmukh, Vitaliy Gorbatyuk, Olga Vinogradova, Debra A Kendall

Proteins· March 2012

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Tyrosine phosphorylation as a conformational switch: a case study of integrin β3 cytoplasmic tail.
Lalit Deshmukh, Nahum Meller, Nathan Alder, Tatiana Byzova, Olga Vinogradova

J Biol Chem· November 2011

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Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain.
Lalit Deshmukh, Vitaliy Gorbatyuk, Olga Vinogradova

J Biol Chem· November 2010

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NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation.
Sergiy Tyukhtenko, Elvis K Tiburu, Lalit Deshmukh, Olga Vinogradova, David R Janero

Biochem Biophys Res Commun· December 2009

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Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments.
Elvis K Tiburu, Sergiy Tyukhtenko, Lalit Deshmukh, Olga Vinogradova, David R Janero

Biochem Biophys Res Commun· June 2009

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The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors.
Jennifer M Beierlein, Lalit Deshmukh, Kathleen M Frey, Olga Vinogradova, Amy C Anderson

Biochemistry· May 2009

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