Publications by authors named "Georg Meisl"

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Inhibiting Disulfide Bonding in Truncated Tau297-391 Results in Enhanced Self-Assembly of Tau into Seed-Competent Assemblies.
Sebastian S Oakley, Karen E Marshall, Georg Meisl, Alice Copsey, Mahmoud B Maina

ACS Chem Neurosci· December 2025

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General integrated rate law for complex self-assembly reactions reveals the mechanism of amyloid-beta coaggregation.
Alexander J Dear, Georg Meisl, Emil Axell, Xiaoting Yang, Risto Cukalevski

Phys Chem Chem Phys· October 2025

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Neurodegeneration emerges at a cellular tipping point between aggregate accumulation and removal.
Matthew W Cotton, Shriram Venkatesan, Joseph S Beckwith, Dorothea Böken, Catherine K Xu, Georg Meisl

bioRxiv· October 2025

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Beyond prion-like spreading in neurodegenerative disease.
Georg Meisl, James B Rowe, David Klenerman

Alzheimers Dement· October 2025

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A Mathematical Model of Cellular Aggregation Predicts Patterns of Tau Accumulation in Neurodegenerative Disease.
Shih-Huan Huang, Annelies Quaegebeur, Tanrada Pansuwan, Timothy Rittman, Ruiyan Wang, Georg Meisl

Adv Sci (Weinh)· October 2025

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Rare bioactive tau oligomers from Alzheimer brain support both templated misfolding and fibril formation.
Noé Quittot, Dhanush Sivasankaran, Dorothea Boeken, Yu Chen, Joshua E Chun, Georg Meisl

bioRxiv· September 2025

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Global kinetic model of lipid-induced -synuclein aggregation and its inhibition by small molecules.
Alisdair Stevenson, Roxine Staats, Alexander J Dear, David Voderholzer, Jesper E Dreier, Georg Meisl

Proc Natl Acad Sci U S A· July 2025

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Small-diffusible aggregates, plaques, tangles, and dynamic equilibria: Untangling Alzheimer's disease.
Emre Fertan, Georg Meisl, David Klenerman

Alzheimers Dement· July 2025

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Kinetics of seeded protein aggregation: Theory and application.
Alexander J Dear, Georg Meisl, Jing Hu, Tuomas P J Knowles, Sara Linse

J Chem Phys· July 2025

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Transforming an ATP-dependent enzyme into a dissipative, self-assembling system.
Yiying Li, Jie Zhu, Zhiyin Zhang, Jiapeng Wei, Fengbin Wang, Georg Meisl

Nat Chem Biol· June 2025

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Kinetics of Amyloid Oligomer Formation.
Jiapeng Wei, Georg Meisl, Alexander J Dear, Thomas C T Michaels, Tuomas P J Knowles

Annu Rev Biophys· May 2025

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Competing addition processes give distinct growth regimes in the assembly of 1D filaments.
Sk Ashif Akram, Tyler Brown, Stephen Whitelam, Georg Meisl, Tuomas P J Knowles

Biophys J· March 2025

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SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy.
Shekhar Kedia, Emre Fertan, Yunzhao Wu, Yu P Zhang, Georg Meisl

Cell Chem Biol· February 2025

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Serine phosphorylation mimics of Aβ form distinct, non-cross-seeding fibril morphs.
Kalyani Sanagavarapu, Georg Meisl, Veronica Lattanzi, Katja Bernfur, Birgitta Frohm

Chem Sci· October 2024

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Design of amyloidogenic peptide traps.
Danny D Sahtoe, Ewa A Andrzejewska, Hannah L Han, Enrico Rennella, Matthias M Schneider, Georg Meisl

Nat Chem Biol· August 2024

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Surface effects on functional amyloid formation.
Alexander J Dear, Georg Meisl, Christopher G Taylor, Umberto Capasso Palmiero, Susanne Nordby Stubbe

Nanoscale· August 2024

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α-Synuclein oligomers form by secondary nucleation.
Catherine K Xu, Georg Meisl, Ewa A Andrzejewska, Georg Krainer, Alexander J Dear

Nat Commun· August 2024

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Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces.
Alexander J Dear, Dev Thacker, Stefan Wennmalm, Lei Ortigosa-Pascual, Ewa A Andrzejewska, Georg Meisl

ACS Chem Neurosci· June 2024

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Kinetic models reveal the interplay of protein production and aggregation.
Jiapeng Wei, Georg Meisl, Alexander Dear, Matthijs Oosterhuis, Ronald Melki

Chem Sci· June 2024

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Molecular mechanism of α-synuclein aggregation on lipid membranes revealed.
Alexander J Dear, Xiangyu Teng, Sarah R Ball, Joshua Lewin, Robert I Horne, Georg Meisl

Chem Sci· May 2024

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Maximum entropy determination of mammalian proteome dynamics.
Alexander J Dear, Gonzalo A Garcia, Georg Meisl, Galen A Collins, Tuomas P J Knowles

Proc Natl Acad Sci U S A· April 2024

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The thermodynamics of neurodegenerative disease.
Georg Meisl

Biophys Rev (Melville)· March 2024

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Self-replication of A aggregates occurs on small and isolated fibril sites.
Samo Curk, Johannes Krausser, Georg Meisl, Daan Frenkel, Sara Linse

Proc Natl Acad Sci U S A· February 2024

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Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on anti-CD20 therapy.
Ashley Priddey, Michael Xin Hua Chen-Xu, Daniel James Cooper, Serena MacMillan, Georg Meisl

Front Immunol· January 2024

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Phase Separation and Fibrillization of Human Annexin A7 Are Mediated by Its Proline-Rich Domain.
Chenrong Yu, Spencer L Nelson, Georg Meisl, Rodolfo Ghirlando, Lalit Deshmukh

Biochemistry· November 2023

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