Publications by authors named "Lance L Simpson"

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RBC Adherence of Immune Complexes Containing Botulinum Toxin Improves Neutralization and Macrophage Uptake.
Fetweh H Al-Saleem, Rashmi Sharma, Rama Devudu Puligedda, Md Elias, Chandana Devi Kattala, Lance L Simpson

Toxins (Basel)· May 2017

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Recombinant rabies virus particles presenting botulinum neurotoxin antigens elicit a protective humoral response in vivo.
Andrew W Hudacek, Fetweh H Al-Saleem, Mallory Willet, Travis Eisemann, Jeffrey A Mattis, Lance L Simpson

Mol Ther Methods Clin Dev· May 2015

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Mechanisms of enhanced neutralization of botulinum neurotoxin by monoclonal antibodies conjugated to antibodies specific for the erythrocyte complement receptor.
Rashmi Sharma, Huiwu Zhao, Fetweh H Al-Saleem, Ahmed Syed Ubaid, Rama Devudu Puligedda, Lance L Simpson

Mol Immunol· February 2014

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Analysis of the mechanisms that underlie absorption of botulinum toxin by the inhalation route.
Fetweh H Al-Saleem, Denise M Ancharski, Suresh G Joshi, M Elias, Ajay Singh, Lance L Simpson

Infect Immun· December 2012

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Epitope characterization of sero-specific monoclonal antibody to Clostridium botulinum neurotoxin type A.
Cindi R Corbett, Erin Ballegeer, Kelly A Weedmark, M D Elias, Fetweh H Al-Saleem, Lance L Simpson

Hybridoma (Larchmt)· December 2011

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Identification of the factors that govern the ability of therapeutic antibodies to provide postchallenge protection against botulinum toxin: a model for assessing postchallenge efficacy of medical countermeasures against agents of bioterrorism and biological warfare.
Fetweh H Al-Saleem, Zidoon Nasser, Rebecca M Olson, Linsen Cao, Lance L Simpson

J Pharmacol Exp Ther· August 2011

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Immunization of mice with the non-toxic HC50 domain of botulinum neurotoxin presented by rabies virus particles induces a strong immune response affording protection against high-dose botulinum neurotoxin challenge.
Waleed Mustafa, Fetweh H Al-Saleem, Zidoon Nasser, Rebecca M Olson, Jeffrey A Mattis, Lance L Simpson

Vaccine· June 2011

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Evidence that botulinum toxin receptors on epithelial cells and neuronal cells are not identical: implications for development of a non-neurotropic vaccine.
Md Elias, Fetweh Al-Saleem, Denise M Ancharski, Ajay Singh, Zidoon Nasser, Lance L Simpson

J Pharmacol Exp Ther· March 2011

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Enhanced neutralization potency of botulinum neurotoxin antibodies using a red blood cell-targeting fusion protein.
Sharad P Adekar, Andrew T Segan, Cindy Chen, Rodney Bermudez, M D Elias, Lance L Simpson

PLoS One· March 2011

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Symptomatic relief of botulinum neurotoxin/a intoxication with aminopyridines: a new twist on an old molecule.
Alexander V Mayorov, Bert Willis, Antonia Di Mola, Derek Adler, Jennifer Borgia, Lance L Simpson

ACS Chem Biol· December 2010

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Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents.
Jorge Sepulveda, Jean Mukherjee, Saul Tzipori, Lance L Simpson, Charles B Shoemaker

Infect Immun· February 2010

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Localization of the sites and characterization of the mechanisms by which anti-light chain antibodies neutralize the actions of the botulinum holotoxin.
Tsuyoshi Takahashi, Suresh G Joshi, Fetweh Al-Saleem, Denise Ancharski, Ajay Singh, Lance L Simpson

Vaccine· April 2009

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The role of systemic handling in the pathophysiologic actions of botulinum toxin.
Fetweh H Al-Saleem, Denise M Ancharski, Easwaran Ravichandran, Suresh G Joshi, Ajay K Singh, Lance L Simpson

J Pharmacol Exp Ther· September 2008

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Neutralization of botulinum neurotoxin by a human monoclonal antibody specific for the catalytic light chain.
Sharad P Adekar, Tsuyoshi Takahashi, R Mark Jones, Fetweh H Al-Saleem, Denise M Ancharski, Lance L Simpson

PLoS One· August 2008

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Hybridoma populations enriched for affinity-matured human IgGs yield high-affinity antibodies specific for botulinum neurotoxins.
Sharad P Adekar, R Mark Jones, M D Elias, Fetweh H Al-Saleem, Michael J Root, Lance L Simpson

J Immunol Methods· April 2008

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A natural human IgM antibody that neutralizes botulinum neurotoxin in vivo.
Sharad P Adekar, Fetweh H Al-Saleem, M D Elias, Katherine A Rybinski, Lance L Simpson

Hybridoma (Larchmt)· April 2008

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A human monoclonal antibody that binds serotype A botulinum neurotoxin.
Sharad P Adekar, R Mark Jones, M D Elias, Fetweh H Al-Saleem, Michael J Root, Lance L Simpson

Hybridoma (Larchmt)· February 2008

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High-throughput homogeneous immunoassay readily identifies monoclonal antibody to serovariant clostridial neurotoxins.
Cindi R Corbett, Mohammad D Elias, Lance L Simpson, Xin-Yong Yuan, Robyn R Cassan

J Immunol Methods· December 2007

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Balancing the benefits and risks of a botulinum toxin vaccine.
Lance L Simpson

Expert Rev Vaccines· December 2007

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Protective immunity against botulism provided by a single dose vaccination with an adenovirus-vectored vaccine.
Mingtao Zeng, Qingfu Xu, Md Elias, Michael E Pichichero, Lance L Simpson

Vaccine· October 2007

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Trivalent vaccine against botulinum toxin serotypes A, B, and E that can be administered by the mucosal route.
Easwaran Ravichandran, Fetweh H Al-Saleem, Denise M Ancharski, Mohammad D Elias, Ajay K Singh, Lance L Simpson

Infect Immun· June 2007

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An initial assessment of the systemic pharmacokinetics of botulinum toxin.
Easwaran Ravichandran, Yujing Gong, Fetweh H Al Saleem, Denise M Ancharski, Suresh G Joshi, Lance L Simpson

J Pharmacol Exp Ther· September 2006

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Visualization of binding and transcytosis of botulinum toxin by human intestinal epithelial cells.
Chowdhury R Ahsan, György Hajnóczky, Andrew B Maksymowych, Lance L Simpson

J Pharmacol Exp Ther· December 2005

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The role of exoproteases in governing intraneuronal metabolism of botulinum toxin.
Lance L Simpson, Andrew B Maksymowych, Hirokazu Kouguchi, Garrett Dubois, Roop S Bora

Protein J· April 2005

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Progress toward development of an inhalation vaccine against botulinum toxin.
Jong-Beak Park, Lance L Simpson

Expert Rev Vaccines· August 2004

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