Publications by authors named "Larry Heimark"

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Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics.
Srikanth Venkatraman, Francisco Velazquez, Stephen Gavalas, Wanli Wu, Kevin X Chen, Larry Heimark

Bioorg Med Chem· January 2014

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Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain.
T K Sasikumar, Li Qiang, Duane A Burnett, William J Greenlee, Cheng Li, Larry Heimark

Bioorg Med Chem Lett· June 2009

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Isolation, structural determination, synthesis and quantitative determination of impurities in Intron-A, leached from a silicone tubing.
Tze-Ming Chan, Birendra Pramanik, Robert Aslanian, Vincent Gullo, Mahesh Patel, Larry Heimark

J Pharm Biomed Anal· February 2009

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Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).
Amin A Nomeir, Birendra N Pramanik, Larry Heimark, Frank Bennett, John Veals

J Mass Spectrom· April 2008

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Ultra-performance liquid chromatography/tandem mass spectrometric determination of diastereomers of SCH 503034 in monkey plasma.
Ganfeng Wang, Yunsheng Hsieh, Kuo-Chi Cheng, Richard A Morrison, Srikanth Venkatraman, Larry Heimark

J Chromatogr B Analyt Technol Biomed Life Sci· June 2007

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Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds.
Hanan K Munayyer, Paul A Mann, Andrew S Chau, Taisa Yarosh-Tomaine, Jonathan R Greene, Larry Heimark

Antimicrob Agents Chemother· October 2004

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Microwave enhanced Akabori reaction for peptide analysis.
Ajay K Bose, Yao Hain Ing, Nina Lavlinskaia, Chaitanya Sareen, Birendra N Pramanik, Larry Heimark

J Am Soc Mass Spectrom· July 2002

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Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis.
Larry Heimark, Petia Shipkova, Jonathan Greene, Hanan Munayyer, Taisa Yarosh-Tomaine

J Mass Spectrom· March 2002

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