Publications by authors named "Lars Linden"

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Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia.
Xiao-Yan Zhao, Andreas Wilmen, Dongli Wang, Xinquan Wang, Maxine Bauzon, Lars Linden

Nat Commun· June 2020

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Preclinical Combination Studies of an FGFR2 Targeted Thorium-227 Conjugate and the ATR Inhibitor BAY 1895344.
Katrine Wickstroem, Urs B Hagemann, Alexander Kristian, Christine Ellingsen, Anette Sommer, Lars Linden

Int J Radiat Oncol Biol Phys· October 2019

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Synergistic Effect of a HER2 Targeted Thorium-227 Conjugate in Combination with Olaparib in a BRCA2 Deficient Xenograft Model.
Katrine Wickstroem, Jenny Karlsson, Christine Ellingsen, Véronique Cruciani, Alexander Kristian, Lars Linden

Pharmaceuticals (Basel)· October 2019

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Synergistic Effect of a Mesothelin-Targeted Th Conjugate in Combination with DNA Damage Response Inhibitors in Ovarian Cancer Xenograft Models.
Katrine Wickstroem, Urs B Hagemann, Véronique Cruciani, Antje M Wengner, Alexander Kristian, Lars Linden

J Nucl Med· September 2019

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Keeping pace with the increasing demand for high quality drug candidates in pharmaceutical research: Development of a new two-step preparative tandem high performance chromatographic system for the purification of antibodies.
Stefan Schmitz, Dorian Leo Schönfeld, Bernhard Freitag, Claudia Götzberger-Schad, Melanie Fischer, Lars Linden

J Chromatogr B Analyt Technol Biomed Life Sci· January 2019

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Biophysical and Sequence-Based Methods for Identifying Monovalent and Bivalent Antibodies with High Colloidal Stability.
Magfur E Alam, Steven B Geng, Christian Bender, Seth D Ludwig, Lars Linden

Mol Pharm· January 2018

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Modular Protein Expression Toolbox (MoPET), a standardized assembly system for defined expression constructs and expression optimization libraries.
Ernst Weber, Jörg Birkenfeld, Jürgen Franz, Uwe Gritzan, Lars Linden

PLoS One· September 2017

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Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer.
Jörg Willuda, Lars Linden, Hans-Georg Lerchen, Charlotte Kopitz, Beatrix Stelte-Ludwig

Mol Cancer Ther· May 2017

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Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform.
Thomas Schirrmann, André Frenzel, Lars Linden, Beatrix Stelte-Ludwig, Jörg Willuda

MAbs· November 2014

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Anetumab ravtansine: a novel mesothelin-targeting antibody-drug conjugate cures tumors with heterogeneous target expression favored by bystander effect.
Sven Golfier, Charlotte Kopitz, Antje Kahnert, Iring Heisler, Christoph A Schatz, Lars Linden

Mol Cancer Ther· June 2014

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Gauging colloidal and thermal stability in human IgG1-sugar solutions through diffusivity measurements.
Jonathan Rubin, Aditi Sharma, Lars Linden, Andreas S Bommarius, Sven H Behrens

J Phys Chem B· March 2014

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With or without sugar? (A)glycosylation of therapeutic antibodies.
Dmitrij Hristodorov, Rainer Fischer, Lars Linden

Mol Biotechnol· July 2013

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Generation and comparative characterization of glycosylated and aglycosylated human IgG1 antibodies.
Dmitrij Hristodorov, Rainer Fischer, Hannah Joerissen, Beate Müller-Tiemann, Heiner Apeler, Lars Linden

Mol Biotechnol· March 2013

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Salt-induced aggregation of a monoclonal human immunoglobulin G1.
Jonathan Rubin, Lars Linden, Wayne M Coco, Andreas S Bommarius, Sven H Behrens

J Pharm Sci· February 2013

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The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase.
Iris M Fritze, Lars Linden, Jörg Freigang, Günter Auerbach, Robert Huber

Plant Physiol· April 2004

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