Publications by authors named "Iring Heisler"

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Mechanistic insights into the selective targeting of P2X3 receptor by camlipixant antagonist.
Trung Thach, KanagaVijayan Dhanabalan, Prajwal Prabhakarrao Nandekar, Seth Stauffer, Iring Heisler

J Biol Chem· January 2025

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A Second Drug Binding Site in P2X3.
Trung Thach, KanagaVijayan Dhanabalan, Prajwal Prabhakarrao Nandekar, Seth Stauffer, Iring Heisler

bioRxiv· June 2024

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Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans.
Steffen R Hahnel, William M Roberts, Iring Heisler, Daniel Kulke, Janis C Weeks

Int J Parasitol Drugs Drug Resist· August 2021

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Caenorhabditis elegans in anthelmintic research - Old model, new perspectives.
Steffen R Hahnel, Clayton M Dilks, Iring Heisler, Erik C Andersen, Daniel Kulke

Int J Parasitol Drugs Drug Resist· December 2020

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Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A.
Anders Friberg, Hartmut Rehwinkel, Duy Nguyen, Vera Pütter, Maria Quanz, Iring Heisler

ACS Omega· June 2020

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Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876.
Holger Siebeneicher, Arwed Cleve, Hartmut Rehwinkel, Roland Neuhaus, Iring Heisler

ChemMedChem· October 2016

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Identification of novel GLUT inhibitors.
Holger Siebeneicher, Marcus Bauser, Bernd Buchmann, Iring Heisler, Thomas Müller

Bioorg Med Chem Lett· April 2016

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Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Khyati Kapoor, Janet S Finer-Moore, Bjørn P Pedersen, Laura Caboni, Andrew Waight, Iring Heisler

Proc Natl Acad Sci U S A· April 2016

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Anetumab ravtansine: a novel mesothelin-targeting antibody-drug conjugate cures tumors with heterogeneous target expression favored by bystander effect.
Sven Golfier, Charlotte Kopitz, Antje Kahnert, Iring Heisler, Christoph A Schatz

Mol Cancer Ther· June 2014

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BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Peter Ellinghaus, Iring Heisler, Kerstin Unterschemmann, Michael Haerter, Hartmut Beck

Cancer Med· October 2013

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Chimeric toxins inhibit growth of primary oral squamous cell carcinoma cells.
Christopher Bachran, Iring Heisler, Diana Bachran, Katrin Dassler, Jürgen Ervens

Cancer Biol Ther· February 2008

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A cleavable molecular adapter reduces side effects and concomitantly enhances efficacy in tumor treatment by targeted toxins in mice.
Hendrik Fuchs, Christopher Bachran, Tongyu Li, Iring Heisler, Horst Dürkop

J Control Release· February 2007

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The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure.
Christopher Bachran, Mark Sutherland, Iring Heisler, Philipp Hebestreit, Matthias F Melzig

Exp Biol Med (Maywood)· April 2006

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Influence of protein transduction domains on target-specific chimeric proteins.
Christopher Bachran, Iring Heisler, Hendrik Fuchs, Mark Sutherland

Biochem Biophys Res Commun· November 2005

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Combined application of saponin and chimeric toxins drastically enhances the targeted cytotoxicity on tumor cells.
Iring Heisler, Mark Sutherland, Christopher Bachran, Philipp Hebestreit, Anna Schnitger

J Control Release· August 2005

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A cleavable adapter to reduce nonspecific cytotoxicity of recombinant immunotoxins.
Iring Heisler, Jutta Keller, Rudolf Tauber, Mark Sutherland, Hendrik Fuchs

Int J Cancer· January 2003

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A colorimetric assay for the quantitation of free adenine applied to determine the enzymatic activity of ribosome-inactivating proteins.
Iring Heisler, Jutta Keller, Rudolf Tauber, Mark Sutherland, Hendrik Fuchs

Anal Biochem· March 2002

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