Publications by authors named "Lars Ohman"

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Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance.
Bradley Zinker, Amanda Mika, Phong Nguyen, Denise Wilcox, Lars Ohman

Metabolism· March 2007

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Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists.
Steven J Richards, Thomas W von Geldern, Peer Jacobson, Denise Wilcox, Phong Nguyen, Lars Ohman

Bioorg Med Chem Lett· December 2006

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Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production.
Dale S Edgerton, Peer B Jacobson, Terry J Opgenorth, Bradley Zinker, David Beno, Lars Ohman

Metabolism· September 2006

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Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
Peer B Jacobson, Thomas W von Geldern, Lars Ohman, Marie Osterland, Jiahong Wang

J Pharmacol Exp Ther· July 2005

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Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.
Thomas W von Geldern, Noah Tu, Philip R Kym, James T Link, Hwan-Soo Jae, Lars Ohman

J Med Chem· August 2004

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The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism.
Björn Kauppi, Clarissa Jakob, Mathias Färnegårdh, Jie Yang, Harri Ahola, Lars Ohman

J Biol Chem· June 2003

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