Publications by authors named "Laura D Attardi"

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Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network.
Anthony M Boutelle, Aicha R Mabene, David Yao, Haiqing Xu, Mengxiong Wang, Laura D Attardi

Cell Death Differ· November 2025

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The legacy of a gentleman scientist: Pierre Hainaut.
Christophe Arnoult, Laura D Attardi, Kerem Batsheva, Giovanni Blandino, Kathleen H Burns

Cell Death Differ· October 2025

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p53 drives lung cancer regression through a TSC2/TFEB-dependent senescence program.
Mengxiong Wang, Kathryn T Bieging-Rolett, Alyssa M Kaiser, Colleen A Brady, John H Lockhart, Laura D Attardi

Cancer Discov· October 2025

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Analysis of knockout mice reveals critical female-specific roles for the Hippo pathway component PTPN14.
Edel M McCrea, Neoklis Makrides, Takako Tabata, Wencke Reineking, José G Vilches-Moure, Laura D Attardi

Genes Dev· September 2025

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Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics.
James Wang, Jai Woong Seo, Aris J Kare, Martin Schneider, Mallesh Pandrala, Laura D Attardi

Nat Commun· December 2024

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Activating p53 with a Mutant-Specific Small Molecule.
Xijun Zhu, Woong Sub Byun, Dominika Ewa Pieńkowska, Kha The Nguyen, Jan Gerhartz, Laura D Attardi

bioRxiv· October 2024

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Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network.
Anthony M Boutelle, Aicha R Mabene, David Yao, Haiqing Xu, Mengxiong Wang, Laura D Attardi

bioRxiv· September 2024

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Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice.
Yuan Pan, Jared D Hysinger, Belgin Yalçın, James J Lennon, Youkyeong Gloria Byun, Laura D Attardi

Nat Neurosci· August 2024

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Author Correction: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Pawel K Mazur, Alexander Herner, Stephano S Mello, Matthias Wirth, Simone Hausmann, Laura D Attardi

Nat Med· July 2024

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p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis I Verginadis, Laura D Attardi

Nat Commun· April 2024

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Targeting p53 gain-of-function activity in cancer therapy: a cautionary tale.
Laura D Attardi, Anthony M Boutelle

Cell Death Differ· February 2024

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Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.
Bo He, Lauren Stoffel, Clifford Jiajun He, Kumsun Cho, Albert M Li, Laura D Attardi

Cell Death Dis· January 2024

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p53 governs an AT1 differentiation programme in lung cancer suppression.
Alyssa M Kaiser, Alberto Gatto, Kathryn J Hanson, Richard L Zhao, Nitin Raj, Laura D Attardi

Nature· July 2023

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p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis Verginadis, Laura D Attardi

bioRxiv· April 2023

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Multifaceted role for p53 in pancreatic cancer suppression.
Stephano S Mello, Brittany M Flowers, Pawel K Mazur, James J Lee, Fabian Müller, Laura D Attardi

Proc Natl Acad Sci U S A· March 2023

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The p53 Transactivation Domain 1-Dependent Response to Acute DNA Damage in Endothelial Cells Protects against Radiation-Induced Cardiac Injury.
Hsuan-Cheng Kuo, Lixia Luo, Yan Ma, Nerissa T Williams, Lorraine da Silva Campos, Laura D Attardi

Radiat Res· August 2022

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The Mettl3 epitranscriptomic writer amplifies p53 stress responses.
Nitin Raj, Mengxiong Wang, Jose A Seoane, Richard L Zhao, Alyssa M Kaiser, Laura D Attardi

Mol Cell· July 2022

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A Balancing Act: p53 Activity from Tumor Suppression to Pathology and Therapeutic Implications.
Mengxiong Wang, Laura D Attardi

Annu Rev Pathol· January 2022

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Puma- and Caspase9-mediated apoptosis is dispensable for p53-driven neural crest-based developmental defects.
Margot E Bowen, Abigail S Mulligan, Aryo Sorayya, Laura D Attardi

Cell Death Differ· July 2021

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A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.
Gerald C Tiu, Craig H Kerr, Craig M Forester, Pallavi S Krishnarao, Hannah D Rosenblatt, Laura D Attardi

Dev Cell· July 2021

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The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.
Eui Jung Moon, Stephano S Mello, Caiyun G Li, Jen-Tsan Chi, Kaushik Thakkar, Laura D Attardi

Nat Commun· July 2021

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An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53.
David J Simon, Deanna M Belsky, Margot E Bowen, Christine Y J Ohn, Melanie K O'Rourke, Laura D Attardi

Dev Cell· April 2021

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Zmat3 splices together p53-dependent tumor suppression.
Kathryn T Bieging-Rolett, Laura D Attardi

Mol Cell Oncol· April 2021

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Cell of Origin Influences Pancreatic Cancer Subtype.
Brittany M Flowers, Hang Xu, Abigail S Mulligan, Kathryn J Hanson, Jose A Seoane, Laura D Attardi

Cancer Discov· March 2021

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P53 orchestrates a complex symphony of cellular processes during oncosuppression.
Liz J Valente, Laura D Attardi

Mol Cell Oncol· January 2021

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