Publications by authors named "Laura Hover"

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Impact of Co-mutations and Transcriptional Signatures in Non-Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial.
Marcelo V Negrao, Alvaro G Paula, David Molkentine, Laura Hover, Monique Nilsson

Clin Cancer Res· March 2025

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The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading.
Niranjan Sudhakar, Larry Yan, Fadia Qiryaqos, Lars D Engstrom, Jade Laguer, Laura D Hover

Mol Cancer Ther· October 2024

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Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Laura D Hover

Science· June 2024

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Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy.
Marc Zuckermann, Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Laura Hover

Mol Cancer· June 2024

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Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Xinyuan Tong, Ayushi S Patel, Eejung Kim, Hongjun Li, Yueqing Chen, Laura Hover

Cancer Cell· March 2024

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MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer.
Lars D Engstrom, Ruth Aranda, Laura Waters, Krystal Moya, Vickie Bowcut, Laura D Hover

Cancer Discov· November 2023

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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
Chen He, Ke Xu, Xiaoyan Zhu, Paige S Dunphy, Brian Gudenas, Laura D Hover

Nat Commun· July 2021

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Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma.
Christopher L Tinkle, Brittany Simone, Jason Chiang, Xiaoyu Li, Kristen Campbell, Laura D Hover

Int J Radiat Oncol Biol Phys· March 2020

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Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes.
Hong Wang, Alexander K Diaz, Timothy I Shaw, Yuxin Li, Mingming Niu, Laura D Hover

Nat Commun· August 2019

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Structure and evolution of double minutes in diagnosis and relapse brain tumors.
Ke Xu, Liang Ding, Ti-Cheng Chang, Ying Shao, Jason Chiang, Laura Hover

Acta Neuropathol· January 2019

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Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma.
Laura D Hover, Philip Owens, Alexander L Munden, Jialiang Wang, Lola B Chambless

Neuro Oncol· July 2016

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Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth.
Laura D Hover, Christian D Young, Neil E Bhola, Andrew J Wilson, Dineo Khabele

Cancer Lett· November 2015

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Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis.
Michael W Pickup, Laura D Hover, Yan Guo, Agnieszka E Gorska, Anna Chytil

Oncotarget· September 2015

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Genomic Analysis of the BMP Family in Glioblastomas.
Laura D Hover, Ty W Abel, Philip Owens

Transl Oncogenomics· May 2015

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BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation.
Michael W Pickup, Laura D Hover, Eleanor R Polikowsky, Anna Chytil, Agnieszka E Gorska

Mol Oncol· January 2015

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Cell of origin determines tumor phenotype in an oncogenic Ras/p53 knockout transgenic model of high-grade glioma.
Sabah O Ghazi, Michelle Stark, Zhiguo Zhao, Bret C Mobley, Alex Munden, Laura Hover

J Neuropathol Exp Neurol· August 2012

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Interleukin-1α mediates the antiproliferative effects of 1,25-dihydroxyvitamin D3 in prostate progenitor/stem cells.
Sophia L Maund, Wendy W Barclay, Laura D Hover, Linara S Axanova, Guangchao Sui

Cancer Res· August 2011

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