Publications by authors named "Laura Lucarini"

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Repurposing Drug Metabolites into Dual β-Adrenergic Receptor-Carbonic Anhydrase Modulators as Potential Tools for Ocular Disorders.
Andrea Ammara, Alessandra Carone, Laura Lucarini, Silvia Sgambellone, Silvia Marri

J Med Chem· September 2025

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Editorial: Exploring new therapeutic frontiers in Glaucoma: from molecular targets to patient outcomes.
Silvia Sgambellone, Arianna Carolina Rosa, Ana Raquel Santiago, Ivana Josimovic, Laura Lucarini

Front Pharmacol· May 2025

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Lasamide Containing Sulfonylpiperazines as Effective Agents for the Management of Glaucoma Associated Symptoms.
Jaydeo T Kilbile, Suryakant B Sapkal, Gioele Renzi, Ilaria D'Agostino, Mohamed Boudjelal, Laura Lucarini

ChemMedChem· December 2024

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Potent and Selective Human 5-HT Serotonin Receptor Antagonists: 4'-Cyano-(N)-methanocarba-adenosines by Synthetic Serendipity.
Dilip K Tosh, Matteo Pavan, Allison A Clark, Josie Lammers, Serafina Villano, Laura Lucarini

J Med Chem· December 2024

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Histamine H receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection.
Silvia Sgambellone, Mohammad A Khanfar, Silvia Marri, Serafina Villano, Patrizia Nardini, Laura Lucarini

Biomed Pharmacother· November 2024

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A high-affinity, cis-on photoswitchable beta blocker to optically control β-adrenergic receptors in vitro and in vivo.
Shuang Shi, Yang Zheng, Joëlle Goulding, Silvia Marri, Laura Lucarini

Biochem Pharmacol· August 2024

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Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy.
Andrea Angeli, Irene Chelli, Laura Lucarini, Silvia Sgambellone, Silvia Marri

J Med Chem· February 2024

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Role of histamine H receptor in the anti-inflammatory pathway of glucocorticoid-induced leucin zipper (GILZ) in a model of lung fibrosis.
Silvia Sgambellone, Marta Febo, Mariaconcetta Durante, Silvia Marri, Serafina Villano, Laura Lucarini

Inflamm Res· November 2023

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NCX 470 Exerts Retinal Cell Protection and Enhances Ophthalmic Artery Blood Flow After Ischemia/Reperfusion Injury of Optic Nerve Head and Retina.
Silvia Sgambellone, Silvia Marri, Serafina Villano, Emanuela Masini, Gustavo Provensi, Laura Lucarini

Transl Vis Sci Technol· September 2023

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Editorial: The challenges of drug repurposing in diseases related to chronic inflammation.
Debora Collotta, Laura Lucarini

Front Pharmacol· July 2023

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Adenosine A Receptor (AAR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice.
Silvia Sgambellone, Silvia Marri, Stefano Catarinicchia, Alessandro Pini, Dilip K Tosh, Laura Lucarini

Int J Mol Sci· November 2022

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NCX 470 Restores Ocular Hemodynamics and Retinal Cell Physiology After ET-1-Induced Ischemia/Reperfusion Injury of Optic Nerve and Retina in Rabbits.
Elena Bastia, Silvia Sgambellone, Laura Lucarini, Gustavo Provensi, Stefania Brambilla

J Ocul Pharmacol Ther· September 2022

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New Insight in Histamine Functions.
Silvia Sgambellone, Silvia Marri, Emanuela Masini, Laura Lucarini

Biomolecules· April 2022

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2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity.
Niccolò Chiaramonte, Andrea Angeli, Silvia Sgambellone, Alessandro Bonardi, Alessio Nocentini, Laura Lucarini

Eur J Med Chem· January 2022

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One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes.
Gioele Vannozzi, Daniela Vullo, Andrea Angeli, Marta Ferraroni, Jacob Combs, Laura Lucarini

J Med Chem· January 2022

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The Histamine H Receptor Participates in the Anti-Neuropathic Effect of the Adenosine A Receptor Agonist IB-MECA: Role of CD4 T Cells.
Laura Micheli, Mariaconcetta Durante, Elena Lucarini, Silvia Sgambellone, Laura Lucarini

Biomolecules· October 2021

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Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection.
Silvia Sgambellone, Laura Lucarini, Cecilia Lanzi, Emanuela Masini

Biomolecules· August 2021

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NCX 1741, a Novel Nitric Oxide-Donating Phosphodiesterase-5 Inhibitor, Exerts Rapid and Long-Lasting Intraocular Pressure-Lowering in Cynomolgus Monkeys.
Elena Bastia, Carol Toris, Jean-Michel Bukowski, Stefania Brambilla, Corinna Galli, Laura Lucarini

J Ocul Pharmacol Ther· May 2021

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D-Tagatose Feeding Reduces the Risk of Sugar-Induced Exacerbation of Myocardial I/R Injury When Compared to Its Isomer Fructose.
Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino

Front Mol Biosci· April 2021

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Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis.
Vittoria Borgonetti, Maria Domenica Sanna, Laura Lucarini, Nicoletta Galeotti

Neurotherapeutics· January 2021

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Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis.
Laura Lucarini, Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Elisabetta Bigagli

Biomolecules· September 2020

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Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action.
Alessandro Bonardi, Alessio Nocentini, Silvia Bua, Jacob Combs, Carrie Lomelino, Laura Lucarini

J Med Chem· July 2020

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Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
Silvia Bua, Laura Lucarini, Laura Micheli, Marta Menicatti, Gianluca Bartolucci

J Med Chem· March 2020

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Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action.
Mohamed Fares, Wagdy M Eldehna, Silvia Bua, Cecilia Lanzi, Laura Lucarini

J Med Chem· March 2020

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Effect of Mediterranean Diet Enriched in High Quality Extra Virgin Olive Oil on Oxidative Stress, Inflammation and Gut Microbiota in Obese and Normal Weight Adult Subjects.
Maria Luisa Eliana Luisi, Laura Lucarini, Barbara Biffi, Elena Rafanelli, Giacomo Pietramellara

Front Pharmacol· November 2019

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