Publications by authors named "Laura M Calvi"

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Targeting IL-1/IRAK1/4 signaling in acute myeloid leukemia stem cells following treatment and relapse.
Tzu-Chieh Ho, Mark W LaMere, Hiroki Kawano, Daniel K Byun, Elizabeth A LaMere, Laura M Calvi

Leukemia· December 2025

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Taurine from tumour niche drives glycolysis to promote leukaemogenesis.
Sonali Sharma, Benjamin J Rodems, Cameron D Baker, Christina M Kaszuba, Edgardo I Franco, Laura M Calvi

Nature· August 2025

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Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis.
Roméo S Blanc, Nidhi Shah, Sarah Hachmer, Noah A S Salama, Fanju W Meng, Laura M Calvi

Nat Aging· August 2025

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Monocytes/macrophages contamination disrupts functional and transcriptional characteristics of murine bone marrow- and bone-derived stromal cells.
Yuko Kawano, Hiroki Kawano, Stephanie Busch, Allison J Li, Jane Zhang, Laura M Calvi

JBMR Plus· June 2025

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Taurine Transporter SLC6A6 Expression Promotes Mesenchymal Stromal Cell Function.
Christina M Kaszuba, Sonali Sharma, Benjamin J Rodems, Cameron D Baker, Palomi Schacht, Laura M Calvi

bioRxiv· June 2025

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Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models.
Jian Ye, Shuyang S Qin, Angela L Hughson, Gary Hannon, Noah A Salama, Laura M Calvi

J Immunother Cancer· May 2025

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IL-1R1 and IL-18 signals regulate mesenchymal stromal cells in an aged murine model of myelodysplastic syndromes.
Yuko Kawano, Hiroki Kawano, Mark W LaMere, Elizabeth A LaMere, Daniel K Byun, Laura M Calvi

Blood· April 2025

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Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.
Angela L Hughson, Gary Hannon, Noah A Salama, Tara G Vrooman, Caroline A Stockwell, Laura M Calvi

Mol Ther Nucleic Acids· December 2024

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Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse.
Tzu-Chieh Ho, Mark W LaMere, Hiroki Kawano, Daniel K Byun, Elizabeth A LaMere, Laura M Calvi

bioRxiv· November 2024

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Ultralow-dose irradiation enables engraftment and intravital tracking of disease initiating niches in clonal hematopoiesis.
Kevin Lee, Wimeth Dissanayake, Melissa MacLiesh, Cih-Li Hong, Zi Yin, Laura M Calvi

Sci Rep· September 2024

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Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging.
Emily R Quarato, Noah A Salama, Laura M Calvi

Curr Osteoporos Rep· August 2024

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Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia.
Benjamin J Rodems, Sonali Sharma, Cameron D Baker, Christina M Kaszuba, Takashi Ito, Laura M Calvi

bioRxiv· May 2024

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The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression.
Youmna S Kfoury, Fei Ji, Esha Jain, Michael Mazzola, Giulia Schiroli, Laura M Calvi

Blood Adv· November 2023

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Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer.
Angela L Hughson, Gary Hannon, Noah A Salama, Tara G Vrooman, Caroline A Stockwell, Laura M Calvi

bioRxiv· November 2023

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Identifying Bone Marrow Microenvironmental Populations in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Christina M Kaszuba, Benjamin J Rodems, Sonali Sharma, Edgardo I Franco, John M Ashton, Laura M Calvi

J Vis Exp· November 2023

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Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling.
Emily R Quarato, Noah A Salama, Allison J Li, Charles O Smith, Jane Zhang, Laura M Calvi

Cell Death Dis· July 2023

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Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1.
Negar Khazan, Emily R Quarato, Niloy A Singh, Cameron W A Snyder, Taylor Moore, Laura M Calvi

Cancers (Basel)· June 2023

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Mitochondrial Transfer to Host Cells from Ex Vivo Expanded Donor Hematopoietic Stem Cells.
Hiroki Kawano, Yuko Kawano, Chen Yu, Mark W LaMere, Matthew J McArthur, Laura M Calvi

Cells· May 2023

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Myelodysplastic syndromes disable human CD271+VCAM1+CD146+ niches supporting normal hematopoietic stem/progenitor cells.
Yuko Kawano, Hiroki Kawano, Dalia Ghoneim, Thomas J Fountaine, Daniel K Byun, Laura M Calvi

bioRxiv· April 2023

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The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies.
Hengwei Zhang, Jane L Liesveld, Laura M Calvi, Brea C Lipe, Lianping Xing

Bone Res· March 2023

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GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity.
Luis I Ruffolo, Katherine M Jackson, Peyton C Kuhlers, Benjamin S Dale, Nathania M Figueroa Guilliani, Laura M Calvi

Gut· July 2022

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Immune Dysfunction, Cytokine Disruption, and Stromal Changes in Myelodysplastic Syndrome: A Review.
Olivia F Lynch, Laura M Calvi

Cells· February 2022

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CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia.
Allison N Seyfried, Amanda McCabe, Julianne N P Smith, Laura M Calvi, Katherine C MacNamara

Leukemia· November 2021

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Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling.
Marian A Ackun-Farmmer, Celia A Soto, Maggie L Lesch, Daniel Byun, Lila Yang, Laura M Calvi

FASEB J· April 2021

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FGF-23: a novel actor in stem cell mobilization.
Laura M Calvi

Blood· March 2021

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