Publications by authors named "Daniel Byun"

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Targeting IL-1/IRAK1/4 signaling in acute myeloid leukemia stem cells following treatment and relapse.
Tzu-Chieh Ho, Mark W LaMere, Hiroki Kawano, Daniel K Byun, Elizabeth A LaMere

Leukemia· December 2025

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The Discovery of GS-1291269: A Neutral Ketohexokinase (KHK) Inhibitor with an Unusual Thietane Amine Functional Group.
Zachary A Kasun, Xiaomin Liang, Ryan D Ferrao, Joshua A Kaplan, Christopher T Clark, Daniel H Byun

J Med Chem· December 2025

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Monocytes/macrophages contamination disrupts functional and transcriptional characteristics of murine bone marrow- and bone-derived stromal cells.
Yuko Kawano, Hiroki Kawano, Stephanie Busch, Allison J Li, Jane Zhang, Daniel K Byun

JBMR Plus· June 2025

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IL-1R1 and IL-18 signals regulate mesenchymal stromal cells in an aged murine model of myelodysplastic syndromes.
Yuko Kawano, Hiroki Kawano, Mark W LaMere, Elizabeth A LaMere, Daniel K Byun

Blood· April 2025

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Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse.
Tzu-Chieh Ho, Mark W LaMere, Hiroki Kawano, Daniel K Byun, Elizabeth A LaMere

bioRxiv· November 2024

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Myelodysplastic syndromes disable human CD271+VCAM1+CD146+ niches supporting normal hematopoietic stem/progenitor cells.
Yuko Kawano, Hiroki Kawano, Dalia Ghoneim, Thomas J Fountaine, Daniel K Byun

bioRxiv· April 2023

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Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling.
Marian A Ackun-Farmmer, Celia A Soto, Maggie L Lesch, Daniel Byun, Lila Yang

FASEB J· April 2021

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Prodrugs of a 1'-CN-4-Aza-7,9-dideazaadenosine -Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV.
Richard L Mackman, Hon C Hui, Michel Perron, Eisuke Murakami, Christopher Palmiotti, Daniel Byun

J Med Chem· April 2021

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Chronic Stress Exposure Suppresses Mammary Tumor Growth and Reduces Circulating Exosome TGF-β Content via β-Adrenergic Receptor Signaling in MMTV-PyMT Mice.
Ryan P Dawes, Kathleen A Burke, Daniel K Byun, Zhou Xu, Petr Stastka

Breast Cancer (Auckl)· June 2020

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The Chemokine CCL3 Regulates Myeloid Differentiation and Hematopoietic Stem Cell Numbers.
Rhonda J Staversky, Daniel K Byun, Mary A Georger, Brandon J Zaffuto, Alexandra Goodman

Sci Rep· October 2018

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Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.
Thorsten A Kirschberg, Sammy Metobo, Michael O Clarke, Vangelis Aktoudianakis, Darius Babusis, Daniel Byun

Bioorg Med Chem Lett· April 2017

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Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy.
Gabriel Ramirez, Ashley R Proctor, Ki Won Jung, Tong Tong Wu, Songfeng Han, Daniel K Byun

Biomed Opt Express· September 2016

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Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.
Michael O Clarke, Richard Mackman, Daniel Byun, Hon Hui, Ona Barauskas

Bioorg Med Chem Lett· June 2015

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Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients.
Aesop Cho, Lijun Zhang, Jie Xu, Rick Lee, Thomas Butler, Daniel Byun

J Med Chem· March 2014

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Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection.
Scott E Lazerwith, Willard Lew, Jennifer Zhang, Philip Morganelli, Qi Liu, Daniel Byun

J Med Chem· March 2014

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Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
Martijn Fenaux, Stacey Eng, Stephanie A Leavitt, Yu-Jen Lee, Eric M Mabery, Daniel Byun

Antimicrob Agents Chemother· February 2013

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Novel, potent and orally bioavailable indolizidinone-derived inhibitors of the hepatitis C virus NS3 protease.
Michael O Clarke, Daniel Byun, Xiaowu Chen, Edward Doerffler, Stephanie A Leavitt

Bioorg Med Chem Lett· January 2012

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The total synthesis of (-)-crispatene.
Aubry K Miller, Daniel H Byun, Christopher M Beaudry, Dirk Trauner

Proc Natl Acad Sci U S A· August 2004

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Wavelength-dependent photofragmentation and photoionization of gaseous (eta4-cycloocta-1,5-diene)(eta5-cyclopentadienyl)cobalt.
Daniel Byun, Jeffrey I Zink

Inorg Chem· July 2003

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