Publications by authors named "Hon Hui"

Claim this Profile
D
Discovery of GS-7682, a Novel 4'-Cyano-Modified -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.
Dustin S Siegel, Hon C Hui, Jared Pitts, Meghan S Vermillion, Kazuya Ishida

J Med Chem· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Comprehensive Review of Cervical Cancer Screening Devices: The Pros and the Cons.
Hui Juen Hon, Pei Pei Chong, Hui Leng Choo, Pwint Phyu Khine

Asian Pac J Cancer Prev· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Prodrugs of a 1'-CN-4-Aza-7,9-dideazaadenosine -Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV.
Richard L Mackman, Hon C Hui, Michel Perron, Eisuke Murakami, Christopher Palmiotti

J Med Chem· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle.
Richard L Mackman, Victoria A Steadman, David K Dean, Petr Jansa, Karine G Poullennec, Hon Hui

J Med Chem· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses.
Dustin Siegel, Hon C Hui, Edward Doerffler, Michael O Clarke, Kwon Chun

J Med Chem· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses.
Michael K Lo, Robert Jordan, Aaron Arvey, Jawahar Sudhamsu, Punya Shrivastava-Ranjan, Hon C Hui

Sci Rep· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.
Travis K Warren, Robert Jordan, Michael K Lo, Adrian S Ray, Richard L Mackman, Hon C Hui

Nature· March 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.
Michael O Clarke, Richard Mackman, Daniel Byun, Hon Hui, Ona Barauskas

Bioorg Med Chem Lett· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study.
Richard L Mackman, Michael Sangi, David Sperandio, Jay P Parrish, Eugene Eisenberg, Hon Hui

J Med Chem· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers, part I: core region.
Hongtao Liu, Lianhong Xu, Hon Hui, Randy Vivian, Christian Callebaut

Bioorg Med Chem Lett· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification and optimization of pteridinone Toll-like receptor 7 (TLR7) agonists for the oral treatment of viral hepatitis.
Paul A Roethle, Ryan M McFadden, Hong Yang, Paul Hrvatin, Hon Hui

J Med Chem· September 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase.
Jay P Parrish, Sharon K Lee, Constantine G Boojamra, Hon Hui, Darius Babusis

Bioorg Med Chem Lett· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improved signal-to-noise ratio performance in magnetic resonance imaging by using a multilayered surface coil array--a simulation study.
Dandan Liang, Hon Tat Hui, Tat Soon Yeo

IEEE J Biomed Health Inform· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Increasing the signal-to-noise ratio by using vertically stacked phased array coils for low-field magnetic resonance imaging.
Dandan Liang, Hon Tat Hui, Tat Soon Yeo

IEEE Trans Inf Technol Biomed· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.
Marcela Krecmerová, Antoín Holý, Graciela Andrei, Karel Pomeisl, Tomás Tichý, Hon Hui

J Med Chem· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.
Richard L Mackman, Adrian S Ray, Hon C Hui, Lijun Zhang, Gabriel Birkus

Bioorg Med Chem· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent.
Adrian S Ray, Jennifer E Vela, Constantine G Boojamra, Lijun Zhang, Hon Hui

Antimicrob Agents Chemother· February 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131.
Tomas Cihlar, Adrian S Ray, Constantine G Boojamra, Lijun Zhang, Hon Hui

Antimicrob Agents Chemother· February 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and anti-HIV activity of cyclic pyrimidine phosphonomethoxy nucleosides and their prodrugs: a comparison of phosphonates and corresponding nucleosides.
Richard L Mackman, Lijun Zhang, Vidya Prasad, Constantine G Boojamra, James Chen, Hon Hui

Nucleosides Nucleotides Nucleic Acids· February 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
Richard L Mackman, Kuei-Ying Lin, Constantine G Boojamra, Hon Hui, Janet Douglas

Bioorg Med Chem Lett· February 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.
Richard L Mackman, Constantine G Boojamra, Vidya Prasad, Lijun Zhang, Kuei-Ying Lin, Hon C Hui

Bioorg Med Chem Lett· December 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.
Richard L Mackman, Lijun Zhang, Vidya Prasad, Constantine G Boojamra, Janet Douglas, Hon Hui

Bioorg Med Chem· August 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors.
Bradley A Katz, Kyle Elrod, Erik Verner, Richard L Mackman, Christine Luong, Hon C Hui

J Mol Biol· May 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
2
2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors.
Richard L Mackman, Hon C Hui, J Guy Breitenbucher, Bradley A Katz, Christine Luong

Bioorg Med Chem Lett· August 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis