Publications by authors named "Laura Macpherson"

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Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.
Shellaina J V Gordon, Florian Perner, Laura MacPherson, Katie A Fennell, Daniela V Wenge

Cancer Discov· October 2025

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mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription.
Tobias D Williams, Ewa M Michalak, Kirstyn T Carey, Enid Y N Lam, Ashley Anderson, Laura MacPherson

Mol Cell· January 2025

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Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.
Shellaina J V Gordon, Florian Perner, Laura MacPherson, Daniela V Wenge, Wallace Bourgeois

bioRxiv· December 2024

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A Preliminary Examination of the Role of Avoidance in Behavioral Activation Treatment Among Latinx Individuals.
Anahi Collado, Emily Blevins, Laura MacPherson

J Lat Psychol· May 2024

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Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.
Andrew A Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic, Wesley Blackaby, David Hardick, Laura MacPherson

Cancer Discov· October 2023

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Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.
Shikhar Sharma, Chi-Yeh Chung, Sean Uryu, Jelena Petrovic, Joan Cao, Laura MacPherson

Cell Chem Biol· October 2023

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Stressor-response functions as a generalizable model for context dependence.
Jordan Rosenfeld, Pedro Gonzalez-Espinosa, Lauren Jarvis, Eva Enders, Matthew Bayly, Laura MacPherson

Trends Ecol Evol· December 2022

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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses.
Kah Lok Chan, Juliana Gomez, Chelisa Cardinez, Nishi Kumari, Christina E Sparbier, Laura Macpherson

Cancer Cell· October 2022

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Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death.
Sylvain Garciaz, Andrew A Guirguis, Sebastian Müller, Fiona C Brown, Yih-Chih Chan, Laura MacPherson

Cancer Discov· March 2022

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Non-genetic determinants of malignant clonal fitness at single-cell resolution.
Katie A Fennell, Dane Vassiliadis, Enid Y N Lam, Luciano G Martelotto, Jesse J Balic, Laura MacPherson

Nature· January 2022

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Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models.
Emma Morrish, Anthony Copeland, Donia M Moujalled, Jason A Powell, Natasha Silke, Laura MacPherson

Blood Adv· October 2020

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Distress Tolerance Interacts With Negative Life Events to Predict Depressive Symptoms Across Adolescence.
Julia W Felton, Anahi Collado, Mazneen Havewala, Julia M Shadur, Laura MacPherson

J Clin Child Adolesc Psychol· May 2020

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HBO1 is required for the maintenance of leukaemia stem cells.
Laura MacPherson, Juliana Anokye, Miriam M Yeung, Enid Y N Lam, Yih-Chih Chan

Nature· January 2020

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A Behavioral Activation Mobile Health App for Smokers With Depression: Development and Pilot Evaluation in a Single-Arm Trial.
Jaimee L Heffner, Noreen L Watson, Edit Serfozo, Kristin E Mull, Laura MacPherson

JMIR Form Res· November 2019

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Mental health stigma in depressed Latinos over the course of therapy: Results from a randomized controlled trial.
Anahi Collado, Michael Zvolensky, Carl Lejuez, Laura MacPherson

J Clin Psychol· July 2019

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Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.
Charles C Bell, Katie A Fennell, Yih-Chih Chan, Florian Rambow, Miriam M Yeung, Laura MacPherson

Nat Commun· June 2019

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Early psychosocial deprivation and adolescent risk-taking: The role of motivation and executive control.
Catalina Kopetz, Jacqueline I Woerner, Laura MacPherson, Carl W Lejuez, Charles A Nelson

J Exp Psychol Gen· February 2019

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An experimental paradigm examining the influence of frustration on risk-taking behavior.
Jennifer M Loya, Katherine L McCauley, Andrea Chronis-Tuscano, Starr Z Chen, Abanoub Gad, Laura MacPherson

Behav Processes· January 2019

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Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity.
Alvin Gomez, Christian Bindesbøll, Somisetty V Satheesh, Giulia Grimaldi, David Hutin, Laura MacPherson

Biochem J· December 2018

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Sex Differences in the Association between Heavy Drinking and Behavioral Distress Tolerance and Emotional Reactivity Among Non-Depressed College Students.
Paola Pedrelli, Laura MacPherson, Amanda J Khan, Benjamin G Shapero, Lauren B Fisher

Alcohol Alcohol· November 2018

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Risk-Taking Propensity in Older Adolescents: Internalizing Symptoms, Gender, and Negative Reinforcement.
Jennifer Dahne, Aaron C Lim, Allison M Borges, Laura MacPherson

Psychiatry· June 2018

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Native freshwater species get out of the way: Prussian carp () impacts both fish and benthic invertebrate communities in North America.
Jonathan L W Ruppert, Cassandra Docherty, Kenton Neufeld, Kyle Hamilton, Laura MacPherson

R Soc Open Sci· October 2017

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Survival of the Fittest: Darwinian Selection Underpins Chemotherapy Resistance in AML.
Laura MacPherson, Mark A Dawson

Cell Stem Cell· September 2017

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The prospective relationship between distress tolerance and cigarette smoking expectancies in adolescence.
Julia M Shadur, Andrew L Ninnemann, Aaron Lim, Carl W Lejuez, Laura MacPherson

Psychol Addict Behav· August 2017

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Click chemistry enables preclinical evaluation of targeted epigenetic therapies.
Dean S Tyler, Johanna Vappiani, Tatiana Cañeque, Enid Y N Lam, Aoife Ward, Laura MacPherson

Science· June 2017

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