Publications by authors named "Laura Pearce"

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Evaluating a Targeted Language Intervention for Children Aged 4-6 Years-Applying an 'Information Carrying Words' Approach.
Sarah Spencer, Laura Pearce, Karlene Calder, Alice Woods, Abigail Andrews

Int J Lang Commun Disord· May 2025

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Accelerating the development of genetically engineered cellular therapies: a framework for extrapolating data across related products.
Mark D Stewart, Michael Kalos, Vicki Coutinho, Marc Better, Jonathan Jazayeri, Laura Pearce

Cytotherapy· July 2024

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Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Andrew Dj Pearson, Claudia Rossig, Crystal Mackall, Nirali N Shah, Andre Baruchel, Laura Pearce

Eur J Cancer· January 2022

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New Guinea has the world's richest island flora.
Rodrigo Cámara-Leret, David G Frodin, Frits Adema, Christiane Anderson, Marc S Appelhans, Laura Pearce

Nature· August 2020

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Trends in the global immuno-oncology landscape.
Jun Tang, Laura Pearce, Jill O'Donnell-Tormey, Vanessa M Hubbard-Lucey

Nat Rev Drug Discov· December 2018

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Trends in the global immuno-oncology landscape.
Jun Tang, Laura Pearce, Jill O'Donnell-Tormey, Vanessa M Hubbard-Lucey

Nat Rev Drug Discov· November 2018

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The global landscape of cancer cell therapy.
Jun Tang, Vanessa M Hubbard-Lucey, Laura Pearce, Jill O'Donnell-Tormey, Aiman Shalabi

Nat Rev Drug Discov· July 2018

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The man who mistook his neuropsychologist for a popstar: when configural processing fails in acquired prosopagnosia.
Ashok Jansari, Scott Miller, Laura Pearce, Stephanie Cobb, Noam Sagiv

Front Hum Neurosci· August 2015

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Functional characterization of obesity-associated variants involving the α and β isoforms of human SH2B1.
Laura R Pearce, Ray Joe, Michael E Doche, Hsiao-Wen Su, Julia M Keogh

Endocrinology· September 2014

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A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity.
Arundhati Dev Borman, Laura R Pearce, Donna S Mackay, Kerstin Nagel-Wolfrum, Alice E Davidson

Hum Mutat· March 2014

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KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.
Laura R Pearce, Neli Atanassova, Matthew C Banton, Bill Bottomley, Agatha A van der Klaauw

Cell· November 2013

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Human SH2B1 mutations are associated with maladaptive behaviors and obesity.
Michael E Doche, Elena G Bochukova, Hsiao-Wen Su, Laura R Pearce, Julia M Keogh

J Clin Invest· December 2012

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Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
Laura R Pearce, Eeva M Sommer, Kei Sakamoto, Stephan Wullschleger, Dario R Alessi

Biochem J· May 2011

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Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).
Laura R Pearce, Gordon R Alton, Daniel T Richter, John C Kath, Laura Lingardo

Biochem J· October 2010

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The nuts and bolts of AGC protein kinases.
Laura R Pearce, David Komander, Dario R Alessi

Nat Rev Mol Cell Biol· January 2010

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New insights into mTOR signaling: mTORC2 and beyond.
Dario R Alessi, Laura R Pearce, Juan M García-Martínez

Sci Signal· April 2009

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Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Laura R Pearce, Xu Huang, Jérôme Boudeau, Rafał Pawłowski, Stephan Wullschleger

Biochem J· August 2007

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Phase II trial of DNA methyltransferase 1 inhibition with the antisense oligonucleotide MG98 in patients with metastatic renal carcinoma: a National Cancer Institute of Canada Clinical Trials Group investigational new drug study.
Eric Winquist, Jennifer Knox, Jean-Pierre Ayoub, Lori Wood, Nancy Wainman, Laura Pearce

Invest New Drugs· March 2006

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Phase III study of N,N-diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine (BMS-217380-01) combined with doxorubicin versus doxorubicin alone in metastatic/recurrent breast cancer: National Cancer Institute of Canada Clinical Trials Group Study MA.19.
Leonard Reyno, Lesley Seymour, Dongsheng Tu, Susan Dent, Karen Gelmon, Laura Pearce

J Clin Oncol· January 2004

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