Publications by authors named "Laura Rapley"

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Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction.
Elizabeth England, D Gareth Rees, Ian Christopher Scott, Sara Carmen, Denice T Y Chan, Laura Rapley

Sci Rep· June 2023

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Sputum biomarkers during acute severe asthma attacks in children-a case-control study.
Manisha Ramphul, Kathryn G Welsh, Richard D May, Michael A Ghebre, Laura Rapley

Acta Paediatr· March 2022

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Interleukin-33 Amplifies Human Mast Cell Activities Induced by Complement Anaphylatoxins.
Peter W West, Rajia Bahri, Karen M Garcia-Rodriguez, Georgia Sweetland, Georgia Wileman, Laura Rapley

Front Immunol· June 2021

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Sputum microbiomic clustering in asthma and chronic obstructive pulmonary disease reveals a Haemophilus-predominant subgroup.
Sarah Diver, Matt Richardson, Koirobi Haldar, Michael A Ghebre, Mohammadali Y Ramsheh, Laura Rapley

Allergy· April 2020

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Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum.
Michael A Ghebre, Pee Hwee Pang, Dhananjay Desai, Beverley Hargadon, Chris Newby, Laura Rapley

BMC Pulm Med· August 2019

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Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma.
Nadia Nicholine Poulsen, Asger Bjerregaard, Siew-Kim Khoo, Ingrid A Laing, Peter Le Souëf, Laura Rapley

Respir Med· July 2018

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Biological exacerbation clusters demonstrate asthma and chronic obstructive pulmonary disease overlap with distinct mediator and microbiome profiles.
Michael A Ghebre, Pee Hwee Pang, Sarah Diver, Dhananjay Desai, Mona Bafadhel, Laura Rapley

J Allergy Clin Immunol· June 2018

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Sputum Inflammatory Mediators Are Increased in Aspergillus fumigatus Culture-Positive Asthmatics.
Michael A Ghebre, Dhananjay Desai, Amisha Singapuri, Joanne Woods, Laura Rapley

Allergy Asthma Immunol Res· March 2017

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Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
Jennifer L Percival-Alwyn, Elizabeth England, Benjamin Kemp, Laura Rapley, Nicola H E Davis

MAbs· September 2015

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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
E Suzanne Cohen, Ian C Scott, Jayesh B Majithiya, Laura Rapley, Benjamin P Kemp

Nat Commun· September 2015

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Biological clustering supports both "Dutch" and "British" hypotheses of asthma and chronic obstructive pulmonary disease.
Michael A Ghebre, Mona Bafadhel, Dhananjay Desai, Suzanne E Cohen, Paul Newbold, Laura Rapley

J Allergy Clin Immunol· January 2015

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Are mast cells instrumental for fibrotic diseases?
Catherine Overed-Sayer, Laura Rapley, Tomas Mustelin, Deborah L Clarke

Front Pharmacol· June 2014

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