Publications by authors named "Richard D May"

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Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction.
Elizabeth England, D Gareth Rees, Ian Christopher Scott, Sara Carmen, Denice T Y Chan, Richard D May

Sci Rep· June 2023

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Sputum biomarkers during acute severe asthma attacks in children-a case-control study.
Manisha Ramphul, Kathryn G Welsh, Richard D May, Michael A Ghebre, Laura Rapley

Acta Paediatr· March 2022

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Immunohistochemical Characterization of the IL-13:IL-4 Receptor α Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
Elena Miranda, Jennifer Roberts, Steven Novick, Jean-Martin Lapointe, Carla Bruijnzeel-Koomen, Richard D May

J Invest Dermatol· February 2021

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Sputum microbiomic clustering in asthma and chronic obstructive pulmonary disease reveals a Haemophilus-predominant subgroup.
Sarah Diver, Matt Richardson, Koirobi Haldar, Michael A Ghebre, Mohammadali Y Ramsheh, Richard D May

Allergy· April 2020

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Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum.
Michael A Ghebre, Pee Hwee Pang, Dhananjay Desai, Beverley Hargadon, Chris Newby, Richard D May

BMC Pulm Med· August 2019

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Biological exacerbation clusters demonstrate asthma and chronic obstructive pulmonary disease overlap with distinct mediator and microbiome profiles.
Michael A Ghebre, Pee Hwee Pang, Sarah Diver, Dhananjay Desai, Mona Bafadhel, Richard D May

J Allergy Clin Immunol· June 2018

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Serum biomarker profiles suggest that atopic dermatitis is a systemic disease.
Judith L Thijs, Ian Strickland, Carla A F M Bruijnzeel-Koomen, Stefan Nierkens, Barbara Giovannone, Richard D May

J Allergy Clin Immunol· April 2018

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EASI p-EASI: Utilizing a combination of serum biomarkers offers an objective measurement tool for disease severity in atopic dermatitis patients.
Judith L Thijs, Julia Drylewicz, Renée Fiechter, Ian Strickland, Matthew A Sleeman, Richard D May

J Allergy Clin Immunol· December 2017

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Moving toward endotypes in atopic dermatitis: Identification of patient clusters based on serum biomarker analysis.
Judith L Thijs, Ian Strickland, Carla A F M Bruijnzeel-Koomen, Stefan Nierkens, Barbara Giovannone, Richard D May

J Allergy Clin Immunol· September 2017

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IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells.
Ana Camelo, Guglielmo Rosignoli, Yoichiro Ohne, Ross A Stewart, Catherine Overed-Sayer, Richard D May

Blood Adv· April 2017

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Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial.
Christopher E Brightling, Pascal Chanez, Richard Leigh, Paul M O'Byrne, Stephanie Korn, Richard D May

Lancet Respir Med· September 2015

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Strategies targeting the IL-4/IL-13 axes in disease.
Richard D May, Michael Fung

Cytokine· September 2015

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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
E Suzanne Cohen, Ian C Scott, Jayesh B Majithiya, Laura Rapley, Benjamin P Kemp, Richard D May

Nat Commun· September 2015

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A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma.
E Suzanne Cohen, Claire L Dobson, Helena Käck, Bing Wang, Dorothy A Sims, Richard D May

MAbs· May 2015

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Biological clustering supports both "Dutch" and "British" hypotheses of asthma and chronic obstructive pulmonary disease.
Michael A Ghebre, Mona Bafadhel, Dhananjay Desai, Suzanne E Cohen, Paul Newbold, Richard D May

J Allergy Clin Immunol· January 2015

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Development of a mouse model mimicking key aspects of a viral asthma exacerbation.
Deborah L Clarke, Nicola H E Davis, Jayesh B Majithiya, Sian C Piper, Arthur Lewis, Richard D May

Clin Sci (Lond)· April 2014

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Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma.
Dhananjay Desai, Christopher Newby, Fiona A Symon, Pranabashis Haldar, Sachil Shah, Richard D May

Am J Respir Crit Care Med· September 2013

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A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma.
Edward Piper, Christopher Brightling, Robert Niven, Chad Oh, Raffaella Faggioni, Richard D May

Eur Respir J· February 2013

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A predictive model of human myelotoxicity using five camptothecin derivatives and the in vitro colony-forming unit granulocyte/macrophage assay.
Noriko Masubuchi, Richard D May, Ryo Atsumi

Clin Cancer Res· October 2004

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Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma.
Chrystalleni Hadjicharalambous, Gordon Dent, Richard D May, Rachel L C Handy, Ian K Anderson

J Allergy Clin Immunol· April 2004

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Fractionation, structural studies, and immunological characterization of the semi-synthetic Quillaja saponins derivative GPI-0100.
Dante J Marciani, Robert C Reynolds, Ashish K Pathak, Kyra Finley-Woodman, Richard D May

Vaccine· September 2003

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Degradation of Quillaja saponaria Molina saponins: loss of the protective effects of a herpes simplex virus 1 subunit vaccine.
Dante J Marcian, Roger G Ptak, Thomas G Voss, Robert C Reynolds, Ashish K Pathak, Richard D May

Int Immunopharmacol· November 2002

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