Publications by authors named "Laura Soucek"

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MYC inhibition by Omomyc causes DNA damage and overcomes PARPi resistance in breast cancer.
Fabio Giuntini, Íñigo González-Larreategui, Andrea Herencia-Ropero, Silvia Casacuberta-Serra, Mariano F Zacarías-Fluck, Laura Soucek

Cell Rep· November 2025

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Corrigendum: Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma.
Mariano F Zacarías-Fluck, Daniel Massó-Vallés, Fabio Giuntini, Íñigo González-Larreategui, Jastrinjan Kaur, Laura Soucek

Genes Dev· September 2025

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MYC-driven gliosis impairs neuron-glia communication in amyotrophic lateral sclerosis.
Paolo Vincenzo Fioretti, Anna Barbieri, Alice Migazzi, Davide Bressan, Maurizio Grassano, Laura Soucek

Brain· September 2025

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MYC in cancer: from undruggable target to clinical trials.
Jonathan R Whitfield, Laura Soucek

Nat Rev Drug Discov· June 2025

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Generation of chimeric antigen receptor T cells targeting p95HER2 in solid tumors.
Macarena Román Alonso, Ariadna Grinyó-Escuer, Santiago Duro-Sánchez, Irene Rius-Ruiz, Marta Bort-Brusca, Laura Soucek

Nat Commun· November 2024

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EV20/Omomyc: A novel dual MYC/HER3 targeting immunoconjugate.
Sandra Bibbò, Emily Capone, Giulio Lovato, Sara Ponziani, Alessia Lamolinara, Laura Soucek

J Control Release· October 2024

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MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer.
Sílvia Casacuberta-Serra, Íñigo González-Larreategui, Daniel Capitán-Leo, Laura Soucek

Signal Transduct Target Ther· August 2024

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MYC targeting by OMO-103 in solid tumors: a phase 1 trial.
Elena Garralda, Marie-Eve Beaulieu, Víctor Moreno, Sílvia Casacuberta-Serra, Sandra Martínez-Martín, Laura Soucek

Nat Med· March 2024

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MYC: there is more to it than cancer.
Mariano F Zacarías-Fluck, Laura Soucek, Jonathan R Whitfield

Front Cell Dev Biol· March 2024

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eIF4A dependency: the hidden key to unlock KRAS mutant non-small cell lung cancer's vulnerability.
Silvia Casacuberta-Serra, Iñigo Gonzalez-Larreategui, Laura Soucek

Transl Lung Cancer Res· December 2023

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Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma.
Mariano F Zacarías-Fluck, Daniel Massó-Vallés, Fabio Giuntini, Íñigo González-Larreategui, Jastrinjan Kaur, Laura Soucek

Genes Dev· April 2023

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Targeting MYC-driven lymphoma: lessons learned and future directions.
Sandra Martínez-Martín, Marie-Eve Beaulieu, Laura Soucek

Cancer Drug Resist· April 2023

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Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue.
Marie-Eve Beaulieu, Sandra Martínez-Martín, Jastrinjan Kaur, Virginia Castillo Cano, Daniel Massó-Vallés, Laura Soucek

Cancers (Basel)· January 2023

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MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding.
Daniel Massó-Vallés, Marie-Eve Beaulieu, Toni Jauset, Fabio Giuntini, Mariano F Zacarías-Fluck, Laura Soucek

Cancer Res Commun· February 2022

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Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma.
Chiara Pighi, Taek-Chin Cheong, Mara Compagno, Enrico Patrucco, Maddalena Arigoni, Laura Soucek

Blood Adv· December 2021

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An "-omycs" Toolbox to Work with MYC.
Jonathan Whitfield, Laura Soucek

Methods Mol Biol· August 2021

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The long journey to bring a Myc inhibitor to the clinic.
Jonathan R Whitfield, Laura Soucek

J Cell Biol· August 2021

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MYC inhibitors in multiple myeloma.
Sandra Martínez-Martín, Laura Soucek

Cancer Drug Resist· August 2021

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The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets.
Mariano F Zacarías-Fluck, Toni Jauset, Sandra Martínez-Martín, Jastrinjan Kaur, Sílvia Casacuberta-Serra, Laura Soucek

Life Sci Alliance· May 2021

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Integrated requirement of non-specific and sequence-specific DNA binding in Myc-driven transcription.
Paola Pellanda, Mattia Dalsass, Marco Filipuzzi, Alessia Loffreda, Alessandro Verrecchia, Laura Soucek

EMBO J· May 2021

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MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.
Nicole M Sodir, Roderik M Kortlever, Valentin J A Barthet, Tania Campos, Luca Pellegrinet, Laura Soucek

Cancer Discov· April 2020

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Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc.
Daniel Massó-Vallés, Laura Soucek

Cells· April 2020

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Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein.
Marie-Eve Beaulieu, Francisco Castillo, Laura Soucek

Cells· April 2020

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MYC, MYCL, and MYCN as therapeutic targets in lung cancer.
Daniel Massó-Vallés, Marie-Eve Beaulieu, Laura Soucek

Expert Opin Ther Targets· February 2020

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Epigenetic Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma.
Rafael Ikemori, Marta Gabasa, Paula Duch, Miguel Vizoso, Paloma Bragado, Laura Soucek

Cancer Res· January 2020

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