Publications by authors named "Roderik M Kortlever"

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A stromal inflammasome Ras safeguard against Myc-driven lymphomagenesis.
Andrew Kent, Kristel Joy Yee Mon, Zachary Hutchins, Gregory Putzel, Dmitry Zhigarev, Roderik M Kortlever

Nat Immunol· January 2025

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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Christopher Abbosh, Alexander M Frankell, Thomas Harrison, Judit Kisistok, Aaron Garnett, Roderik M Kortlever

Nature· April 2023

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Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.
Nicole M Sodir, Luca Pellegrinet, Roderik M Kortlever, Tania Campos, Yong-Won Kwon

Nat Commun· November 2022

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MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.
Nicole M Sodir, Roderik M Kortlever, Valentin J A Barthet, Tania Campos, Luca Pellegrinet

Cancer Discov· April 2020

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Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling.
Peter Kreuzaler, Matthew A Clarke, Elizabeth J Brown, Catherine H Wilson, Roderik M Kortlever

Proc Natl Acad Sci U S A· October 2019

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Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.
Roderik M Kortlever, Nicole M Sodir, Catherine H Wilson, Deborah L Burkhart, Luca Pellegrinet

Cell· November 2017

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A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.
Björn von Eyss, Laura A Jaenicke, Roderik M Kortlever, Nadine Royla, Katrin E Wiese

Cancer Cell· December 2015

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Selective activation of p53-mediated tumour suppression in high-grade tumours.
Melissa R Junttila, Anthony N Karnezis, Daniel Garcia, Francesc Madriles, Roderik M Kortlever

Nature· November 2010

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Transforming growth factor-beta requires its target plasminogen activator inhibitor-1 for cytostatic activity.
Roderik M Kortlever, Jeroen H Nijwening, René Bernards

J Biol Chem· September 2008

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Suppression of the p53-dependent replicative senescence response by lysophosphatidic acid signaling.
Roderik M Kortlever, Thijn R Brummelkamp, Laurens A van Meeteren, Wouter H Moolenaar, René Bernards

Mol Cancer Res· September 2008

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Senescence, wound healing and cancer: the PAI-1 connection.
Roderik M Kortlever, René Bernards

Cell Cycle· December 2006

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Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.
Roderik M Kortlever, Paul J Higgins, René Bernards

Nat Cell Biol· August 2006

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TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.
Thijn R Brummelkamp, Roderik M Kortlever, Merel Lingbeek, Flavia Trettel, Marcy E MacDonald

J Biol Chem· February 2002

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