Publications by authors named "Lay-Kien Yang"

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Mutations in the Substrate-Binding Pocket of DiacylGlycerol Acyltransferase Alter the Fatty Acid Composition of Triacylglycerides in Yeast.
Nazreen V M Abdul Muthaliff, Nur Eka Fitriani, Derek Smith, Jing Sen Ong, Lay Kien Yang

ACS Synth Biol· September 2025

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Tandem mass spectral metabolic profiling of 54 actinobacterial strains and their 459 mutants.
Dillon W P Tay, Lee Ling Tan, Elena Heng, Nadiah Zulkarnain, Elaine Jinfeng Chin, Lay Kien Yang

Sci Data· September 2024

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Reversing the directionality of reactions between non-oxidative pentose phosphate pathway and glycolytic pathway boosts mycosporine-like amino acid production in Saccharomyces cerevisiae.
Miselle Tiana Hengardi, Cui Liang, Keshiniy Madivannan, Lay Kien Yang, Lokanand Koduru

Microb Cell Fact· May 2024

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Application of Cas12j for Editing.
Lee Ling Tan, Elena Heng, Chung Yan Leong, Veronica Ng, Lay Kien Yang

Biomolecules· April 2024

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Exploring a general multi-pronged activation strategy for natural product discovery in Actinomycetes.
Dillon W P Tay, Lee Ling Tan, Elena Heng, Nadiah Zulkarnain, Kuan Chieh Ching, Lay Kien Yang

Commun Biol· January 2024

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Transcriptomic and metabolomic characterization of antibacterial activity of .
Wee Han Poh, Nur Syahirah Ruhazat, Lay Kien Yang, Devendra Shivhare, Peng Ken Lim

Front Plant Sci· September 2023

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Natural Products from Singapore Soil-Derived Family and Evaluation of Their Biological Activities.
Elaine-Jinfeng Chin, Kuan-Chieh Ching, Zann Y Tan, Mario Wibowo, Chung-Yan Leong, Lay-Kien Yang

Molecules· August 2023

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Cost-effective hybrid long-short read assembly delineates alternative GC-rich hosts for natural product discovery.
Elena Heng, Lee Ling Tan, Dillon W P Tay, Yee Hwee Lim, Lay-Kien Yang

Synth Syst Biotechnol· June 2023

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β-Cryptoxanthin Production in by Optimization of the Cytochrome P450 CYP97H1 Activity.
Thomas Lautier, Derek J Smith, Lay Kien Yang, Xixian Chen, Congqiang Zhang

J Agric Food Chem· March 2023

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Cytochrome P450 Surface Domains Prevent the β-Carotene Monohydroxylase CYP97H1 of from Acting as a Dihydroxylase.
Thomas Lautier, Derek J Smith, Lay Kien Yang, Xixian Chen, Congqiang Zhang

Biomolecules· February 2023

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Antibacterial Thiopeptide GE2270-Congeners from .
Kuan-Chieh Ching, Elaine J Chin, Mario Wibowo, Zann Y Tan, Lay-Kien Yang

Molecules· December 2022

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Antibacterial Spirotetronate Polyketides from an sp. Strain A30804.
Kuan-Chieh Ching, Elaine J Chin, Mario Wibowo, Zann Y Tan, Lay-Kien Yang

Molecules· November 2022

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Chemical elicitation as an avenue for discovery of bioactive compounds from fungal endophytes.
Madhaiyan Munusamy, Kuan Chieh Ching, Lay Kien Yang, Sharon Crasta, Martin Muthee Gakuubi

Front Chem· November 2022

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Diethyl phthalate (DEP) perturbs nitrogen metabolism in Saccharomyces cerevisiae.
Corinna Jie Hui Goh, Liang Cui, Jin Huei Wong, Jacqueline Lewis, Megan Goh, Lay Kien Yang

Sci Rep· June 2022

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Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment.
Alex Wong, Sixun Chen, Lay Kien Yang, Yoganathan Kanagasundaram, Karen Crasta

Cell Death Discov· November 2018

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Potent tocolytic activity of ethyl acetate fraction of Ananas comosus on rat and human uteri.
Faezeh Monji, Lang Chu Lau, Abrar Al-Mahmood Siddiquee, Baharudin Bin Said, Lay-Kien Yang

Biomed Pharmacother· September 2018

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Role of the serotonergic pathway in uterotonic activity of Ananas comosus (L.) Merr. - An in vitro and in vivo study.
Faezeh Monji, P Ganesan Adaikan, Lang Chu Lau, Abrar Al-Mahmood Siddiquee, Baharudin Bin Said, Lay-Kien Yang

Phytomedicine· September 2018

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Isolation and Identification of an Anthracimycin Analogue from , a Halophile from a Saltern, by Genomic Mining Strategy.
Fernanda L Sirota, Falicia Goh, Kia-Ngee Low, Lay-Kien Yang, Sharon C Crasta

J Genomics· May 2018

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Pyrrole carboxamidine tryptase inhibitors from Leptonychia pubescens.
Lay Kien Yang, Sok Peng Ng, Horst Flotow, K Yoganathan, B O Daramola

Planta Med· November 2005

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Cochlioquinones and epi-cochlioquinones: antagonists of the human chemokine receptor CCR5 from Bipolaris brizae and Stachybotrys chartarum.
K Yoganathan, Lay-kien Yang, Christine Rossant, Yicun Huang, Siewbee Ng

J Antibiot (Tokyo)· January 2004

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Identification of chelerythrine as an inhibitor of BclXL function.
Shing-Leng Chan, Mei Chin Lee, Kuan Onn Tan, Lay-Kien Yang, Alex S Y Lee, Nai Yang Fu

J Biol Chem· June 2003

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