Publications by authors named "Layla Saidi"

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CHIP protects lysosomes from CLN4 mutant-induced membrane damage.
Juhyung Lee, Natalie Chin, Jizhong Zou, Wan Nur Atiqah Binti Mazli, Michal Jarnik, Layla Saidi

Nat Cell Biol· September 2025

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NEMF-mediated CAT tailing facilitates translocation-associated quality control.
Amanda Ennis, Lihui Wang, Yue Xu, Layla Saidi, Xiaorong Wang

J Cell Biol· June 2025

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CHIP protects lysosomes from CLN4 mutant-induced membrane damages.
Juhyung Lee, Jizhong Zou, Wan Nur Atiqah Binti Mazli, Natalie Chin, Michal Jarnik, Layla Saidi

bioRxiv· February 2025

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NEMF-mediated CAT-tailing defines distinct branches of translocation-associated quality control.
Amanda Ennis, Lihui Wang, Xiaorong Wang, Clinton Yu, Layla Saidi

bioRxiv· August 2024

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Mono-UFMylation promotes misfolding-associated secretion of α-synuclein.
Lihui Wang, Yue Xu, Tetsunari Fukushige, Layla Saidi, Xiaorong Wang

Sci Adv· March 2024

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Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation.
Qi Zhang, Weichun Tang, Eduardo Stancanelli, Eunkyung Jung, Zulfeqhar Syed, Layla Saidi

Nat Commun· September 2023

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Heparan sulfate promotes ACE2 super-cluster assembly to enhance SARS-CoV-2-associated syncytium formation.
Qi Zhang, Wei-Chun Tang, Eduardo Stancanelli, Eunkyung Jung, Zulfeqhar Syed, Layla Saidi

Res Sq· March 2023

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Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation.
Juhyung Lee, Yue Xu, Layla Saidi, Miao Xu, Konrad Zinsmaier

Autophagy· January 2023

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UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis.
Lihui Wang, Yue Xu, Heather Rogers, Layla Saidi, Constance Tom Noguchi

Cell Res· January 2020

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Secretion of misfolded cytosolic proteins from mammalian cells is independent of chaperone-mediated autophagy.
Juhyung Lee, Yue Xu, Ting Zhang, Lei Cui, Layla Saidi

J Biol Chem· September 2018

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DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins.
Yue Xu, Lei Cui, Anthony Dibello, Lihui Wang, Juhyung Lee, Layla Saidi

Cell Discov· March 2018

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Crystal structure and allosteric activation of protein kinase C βII.
Thomas A Leonard, Bartosz Różycki, Layla F Saidi, Gerhard Hummer, James H Hurley

Cell· January 2011

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Hybrid structural model of the complete human ESCRT-0 complex.
Xuefeng Ren, Daniel P Kloer, Young C Kim, Rodolfo Ghirlando, Layla F Saidi

Structure· March 2009

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Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin.
Bertram Canagarajah, Federico Coluccio Leskow, Jonathan Yew Seng Ho, Harald Mischak, Layla F Saidi

Cell· October 2004

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[3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP.
Jackie D Corbin, Mitsi A Blount, James L Weeks, Alfreda Beasley, Karl P Kuhn, Layla F Saidi

Mol Pharmacol· June 2003

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Structure of the GAT domain of human GGA1: a syntaxin amino-terminal domain fold in an endosomal trafficking adaptor.
Silke Suer, Saurav Misra, Layla F Saidi, James H Hurley

Proc Natl Acad Sci U S A· April 2003

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Structural genomics and signaling domains.
James H Hurley, D Eric Anderson, Bridgette Beach, Bertram Canagarajah, Yew Seng Jonathan Ho, Layla Saidi

Trends Biochem Sci· January 2002

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