Publications by authors named "Leah M Prentice"

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The practice of genomic medicine: A delineation of the process and its governing principles.
Julia Handra, Adrienne Elbert, Nour Gazzaz, Ashley Moller-Hansen, Stephanie Hyunh, Leah M Prentice

Front Med (Lausanne)· January 2023

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The Clinical Variant Analysis Tool: Analyzing the evidence supporting reported genomic variation in clinical practice.
Hui-Lin Chin, Nour Gazzaz, Stephanie Huynh, Iulia Handra, Lynn Warnock, Leah M Prentice

Genet Med· July 2022

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Optimization of magnetic bead-based nucleic acid extraction for SARS-CoV-2 testing using readily available reagents.
Simon Haile, Aidan M Nikiforuk, Pawan K Pandoh, David D W Twa, Duane E Smailus, Leah M Prentice

J Virol Methods· January 2022

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Major p53 immunohistochemical patterns in in situ and invasive squamous cell carcinomas of the vulva and correlation with TP53 mutation status.
Basile Tessier-Cloutier, Kim E Kortekaas, Emily Thompson, Jennifer Pors, Julia Chen, Leah M Prentice

Mod Pathol· August 2020

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Selumetinib in patients receiving standard pemetrexed and platinum-based chemotherapy for advanced or metastatic KRAS wildtype or unknown non-squamous non-small cell lung cancer: A randomized, multicenter, phase II study. Canadian Cancer Trials Group (CCTG) IND.219.
Barbara Melosky, Penelope Bradbury, Dongsheng Tu, Marie Florescu, Anthony Reiman, Leah M Prentice

Lung Cancer· July 2019

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Leah M Prentice, Ruth R Miller, Jeff Knaggs, Alborz Mazloomian, Rosalia Aguirre Hernandez

PLoS One· August 2018

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Ciliated muconodular papillary tumors of the lung with KRAS/BRAF/AKT1 mutation.
Emiko Udo, Bungo Furusato, Kazuko Sakai, Leah M Prentice, Tomonori Tanaka

Diagn Pathol· August 2017

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Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.
Yi Kan Wang, Ali Bashashati, Michael S Anglesio, Dawn R Cochrane, Diljot S Grewal, Leah M Prentice

Nat Genet· June 2017

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Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.
Andrew McPherson, Andrew Roth, Emma Laks, Tehmina Masud, Ali Bashashati, Leah M Prentice

Nat Genet· July 2016

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Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden.
Michael S Anglesio, Ali Bashashati, Yi Kan Wang, Janine Senz, Gavin Ha, Leah M Prentice

J Pathol· June 2015

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TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data.
Gavin Ha, Andrew Roth, Jaswinder Khattra, Julie Ho, Damian Yap, Leah M Prentice

Genome Res· November 2014

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Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4.
Pilar Ramos, Anthony N Karnezis, David W Craig, Aleksandar Sekulic, Megan L Russell, Leah M Prentice

Nat Genet· May 2014

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Type-specific cell line models for type-specific ovarian cancer research.
Michael S Anglesio, Kimberly C Wiegand, Nataliya Melnyk, Christine Chow, Clara Salamanca, Leah M Prentice

PLoS One· April 2014

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Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.
Melissa K McConechy, Jiarui Ding, Janine Senz, Winnie Yang, Nataliya Melnyk, Leah M Prentice

Mod Pathol· January 2014

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Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.
Ali Bashashati, Gavin Ha, Alicia Tone, Jiarui Ding, Leah M Prentice

J Pathol· September 2013

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Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research.
Michael S Anglesio, Kimberly C Wiegand, Nataliya Melnyk, Christine Chow, Clara Salamanca, Leah M Prentice

PLoS One· September 2013

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Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study.
Weiva Sieh, Martin Köbel, Teri A Longacre, David D Bowtell, Anna deFazio, Leah M Prentice

Lancet Oncol· August 2013

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Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors.
Anamaria Crisan, Rodrigo Goya, Gavin Ha, Jiarui Ding, Leah M Prentice

PLoS One· May 2013

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BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma.
Jessica N McAlpine, Henry Porter, Martin Köbel, Brad H Nelson, Leah M Prentice

Mod Pathol· May 2012

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The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Sohrab P Shah, Andrew Roth, Rodrigo Goya, Arusha Oloumi, Gavin Ha, Leah M Prentice

Nature· April 2012

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Mll5 is required for normal spermatogenesis.
Damian B Yap, David C Walker, Leah M Prentice, Steven McKinney, Gulisa Turashvili

PLoS One· March 2012

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14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma.
Cheng-Han Lee, Wen-Bin Ou, Adrian Mariño-Enriquez, Meijun Zhu, Mark Mayeda, Leah M Prentice

Proc Natl Acad Sci U S A· January 2012

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Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas.
Melissa K McConechy, Michael S Anglesio, Steve E Kalloger, Winnie Yang, Janine Senz, Leah M Prentice

J Pathol· April 2011

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The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent.
Leah M Prentice, Xavier d'Anglemont de Tassigny, Steven McKinney, Teresa Ruiz de Algara, Damian Yap

BMC Genomics· April 2011

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Ovarian carcinoma subtypes are different diseases: implications for biomarker studies.
Martin Köbel, Steve E Kalloger, Niki Boyd, Steven McKinney, Erika Mehl, Leah M Prentice

PLoS Med· December 2008

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