Publications by authors named "Leanne Winner"

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Evaluation of neuroretina following i.v. or intra-CSF AAV9 gene replacement in mice with MPS IIIA, a childhood dementia.
Helen Beard, Leanne Winner, Andrew Shoubridge, Emma Parkinson-Lawrence, Adeline A Lau

CNS Neurosci Ther· August 2024

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Repetitive, non-invasive imaging of neurodegeneration, and prevention of it with gene replacement, in mice with Sanfilippo syndrome.
Kim M Hemsley, Helen Beard, Glyn Chidlow, Teresa Mammone, Leanne K Winner

Exp Neurol· January 2024

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Biomarkers for predicting disease course in Sanfilippo syndrome: An urgent unmet need in childhood-onset dementia.
Leanne K Winner, Mary-Louise Rogers, Marten F Snel, Kim M Hemsley

J Neurochem· August 2023

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The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.
Leanne K Winner, Helen Beard, Litsa Karageorgos, Nicholas J Smith, John J Hopwood

Biochim Biophys Acta Mol Basis Dis· April 2023

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AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains.
Michaël Hocquemiller, Kim M Hemsley, Meghan L Douglass, Sarah J Tamang, Daniel Neumann, Leanne K Winner

Mol Ther Methods Clin Dev· June 2020

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Evaluation of Disease Lesions in the Developing Canine MPS IIIA Brain.
Leanne K Winner, Neil R Marshall, Robert D Jolly, Paul J Trim, Stephen K Duplock

JIMD Rep· June 2018

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A Preclinical Study Evaluating AAVrh10-Based Gene Therapy for Sanfilippo Syndrome.
Leanne K Winner, Helen Beard, Sofia Hassiotis, Adeline A Lau, Amanda J Luck

Hum Gene Ther· May 2016

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Delivery of therapeutic protein for prevention of neurodegenerative changes: comparison of different CSF-delivery methods.
Neil R Marshall, Sofia Hassiotis, Barbara King, Tina Rozaklis, Paul J Trim, Leanne K Winner

Exp Neurol· January 2015

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Neonatal Bone Marrow Transplantation in MPS IIIA Mice.
Adeline A Lau, N Jannah Shamsani, Leanne K Winner, Sofia Hassiotis, Barbara M King

JIMD Rep· February 2013

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Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.
Kathleen M Knights, Leanne K Winner, David J Elliot, Kushari Bowalgaha, John O Miners

Br J Clin Pharmacol· September 2009

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Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation.
Verawan Uchaipichat, Leanne K Winner, Peter I Mackenzie, David J Elliot, J Andrew Williams

Br J Clin Pharmacol· April 2006

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