Publications by authors named "Leena Halim"

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pTα enhances mRNA translation and potentiates CAR T cells for solid tumor eradication.
Yuzhe Shi, Michael A Lopez, Ivan S Kotchetkov, Nayan Jain, Zeguo Zhao, Leena Halim

Cell· December 2025

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Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation.
Leena Halim, Kushal K Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli

Front Immunol· April 2022

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Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors.
Tamara Muliaditan, Leena Halim, Lynsey M Whilding, Benjamin Draper, Daniela Y Achkova

Cell Rep Med· December 2021

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TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer.
Richard E Beatson, Ana C Parente-Pereira, Leena Halim, Domenico Cozzetto, Caroline Hull

Cell Rep Med· December 2021

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CAR T-cell immunotherapy of B-cell malignancy: the story so far.
Leena Halim, John Maher

Ther Adv Vaccines Immunother· May 2020

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CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies.
Lynsey M Whilding, Leena Halim, Benjamin Draper, Ana C Parente-Pereira, Tomasz Zabinski

Cancers (Basel)· May 2019

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Pre-clinical development of chimeric antigen receptor T-cell immunotherapy: Implications of design for efficacy and safety.
Leena Halim, Adam Ajina, John Maher

Best Pract Res Clin Haematol· June 2018

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An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment.
Leena Halim, Marco Romano, Reuben McGregor, Isabel Correa, Polychronis Pavlidis

Cell Rep· July 2017

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Prospects for immunotherapy of acute myeloid leukemia using γδ T cells.
Leena Halim, Ana Catarina Parente-Pereira, John Maher

Immunotherapy· January 2017

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