Publications by authors named "Leli Zeng"

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Engineering CRISPR System-Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen

Adv Mater· October 2025

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Branched-Chain α Keto-Acid Dehydrogenase Kinase-Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance.
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Leli Zeng

Adv Sci (Weinh)· October 2025

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Targeting metalloptosis in tumor therapy: from molecular mechanisms to application of metal nanoparticles.
Jinxiang Wang, Qin Tian, Yuchen Liu, Chao-Yun Cai, Shuying Fu, Leli Zeng

Mol Cancer· October 2025

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dbscATAC: a resource of single-cell super-enhancers/enhancers and gene markers derived from scATAC-seq data.
Yingmei Li, Shahid Ullah, Yumei Xian, Yazhou Sun, Zilong Zheng, Leli Zeng

Bioinformatics· July 2025

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Organoid models of drug resistant gastric adenosquamous carcinoma: Recapitulating tumor features and refining precision treatment.
Kuan Li, Wenchao Li, Shuying Fu, Chen Wang, Kexin Wang, Leli Zeng

Drug Resist Updat· March 2025

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The important role of lactylation in regulating DNA damage repair and tumor chemotherapy resistance.
Jia Li, Zhe-Sheng Chen, Yihang Pan, Leli Zeng

Drug Resist Updat· January 2025

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m6A demethylation of NNMT in CAFs promotes gastric cancer progression by enhancing macrophage M2 polarization.
Tsz Kin Mak, Kuan Li, Zidan Zhao, Kexin Wang, Leli Zeng

Cancer Lett· December 2024

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The correlation between cancer stem cells and epithelial-mesenchymal transition: molecular mechanisms and significance in cancer theragnosis.
Zi-Ning Lei, Qiu-Xu Teng, Jagadish Koya, Yangruiyu Liu, Zizhou Chen, Leli Zeng

Front Immunol· October 2024

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DDR1 Drives Malignant Progression of Gastric Cancer by Suppressing HIF-1α Ubiquitination and Degradation.
Zhewei Wei, Jin Li, Li Zhong, Dongjie Yang, Wuguo Li, Leli Zeng

Adv Sci (Weinh)· September 2024

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Patient derived cancer organoids model the response to HER2-CD3 bispecific antibody (BsAbHER2) generated from hydroxyapatite gene delivery system.
Yuhong Liu, Chen Wang, Guochuang Chen, Junzong Chen, Wei Chen, Leli Zeng

Cancer Lett· August 2024

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OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
Hongfa Wei, Wenchao Li, Leli Zeng, Ni Ding, Kuan Li

Mol Cancer· June 2024

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RN486, a Bruton's Tyrosine Kinase inhibitor, antagonizes multidrug resistance in ABCG2-overexpressing cancer cells.
Xing-Duo Dong, Qisi Lu, Yi-Dong Li, Chao-Yun Cai, Qiu-Xu Teng, Zeng-Hui Wei, Leli Zeng

J Transl Int Med· June 2024

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NIFK, a Potential Prognostic and Immunological Biomarker in Pan-- Cancer Analysis, Significantly Regulates Proliferation and Metastasis of Colorectal Cancer.
Zhuoyuan Li, Shangbo Zhou, Ting Bin, Yuntao Shi, Leli Zeng

Recent Pat Anticancer Drug Discov· April 2024

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Tyrosine phosphorylation-mediated YAP1-TFAP2A interactions coordinate transcription and trastuzumab resistance in HER2+ breast cancer.
Hailin Zou, Juan Luo, Yibo Guo, Liang Deng, Leli Zeng

Drug Resist Updat· March 2024

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Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression.
Cuncan Deng, Mingyu Huo, Hongwu Chu, Xiaomei Zhuang, Guofei Deng, Leli Zeng

Mol Cancer· March 2024

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Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer.
Huan Yang, Xing Xiao, Leli Zeng, Haiteng Zeng, Yueyuan Zheng

J Transl Med· February 2024

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Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer.
Han Wang, Zhijun Zhou, Junchang Zhang, Tengfei Hao, Pengliang Wang, Leli Zeng

Cancer Lett· January 2024

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Inhibition of phosphoglycerate dehydrogenase induces ferroptosis and overcomes enzalutamide resistance in castration-resistant prostate cancer cells.
Jinxiang Wang, Leli Zeng, Nisha Wu, Yanling Liang, Jie Jin, Fangyin Zeng

Drug Resist Updat· September 2023

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PUM1 Promotes Tumor Progression by Activating DEPTOR-Meditated Glycolysis in Gastric Cancer.
Songcheng Yin, Huifang Liu, Zhijun Zhou, Xiaoyu Xu, Pengliang Wang, Leli Zeng

Adv Sci (Weinh)· September 2023

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Understanding and targeting resistance mechanisms in cancer.
Zi-Ning Lei, Qin Tian, Qiu-Xu Teng, John N D Wurpel, Leli Zeng

MedComm (2020)· June 2023

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Comprehensive analysis of 33 human cancers reveals clinical implications and immunotherapeutic value of the solute carrier family 35 member A2.
Shengshan Xu, Xiguang Chen, Jianxiong Fang, Hongyu Chu, Shuo Fang, Leli Zeng

Front Immunol· June 2023

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Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases.
Qiang Wang, Peng Liu, Yingfei Wen, Kuan Li, Bo Bi, Leli Zeng

Mol Cancer· June 2023

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Comprehensive analysis to construct a novel immune-related prognostic panel in aging-related gastric cancer based on the lncRNA‒miRNA-mRNA ceRNA network.
Cuncan Deng, Juzheng Peng, Cheng Yuan, Huafu Li, Wenchao Li, Leli Zeng

Front Mol Biosci· May 2023

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Advances in immunology and immunotherapy for mesenchymal gastrointestinal cancers.
Bo Li, Hui Chen, Shaohua Yang, Feng Chen, Liangliang Xu, Leli Zeng

Mol Cancer· April 2023

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An Enzyme-Engineered Nonporous Copper(I) Coordination Polymer Nanoplatform for Cuproptosis-Based Synergistic Cancer Therapy.
Yuzhi Xu, Si-Yang Liu, Leli Zeng, Hansu Ma, Yanfei Zhang

Adv Mater· March 2023

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