Publications by authors named "Qiu-Xu Teng"

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Mobocertinib antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells: In vitro and in vivo studies.
Xing-Duo Dong, Meng Zhang, Qiu-Xu Teng, Zi-Ning Lei, Chao-Yun Cai

Cancer Lett· December 2024

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Cell-Based Screen Identifies a Highly Potent and Orally Available ABCB1 Modulator for Treatment of Multidrug Resistance.
Shuai Wang, Sai-Qi Wang, Xiao-Bing Chen, Qian Xu, Hao Deng, Qiu-Xu Teng

J Med Chem· November 2024

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The correlation between cancer stem cells and epithelial-mesenchymal transition: molecular mechanisms and significance in cancer theragnosis.
Zi-Ning Lei, Qiu-Xu Teng, Jagadish Koya, Yangruiyu Liu, Zizhou Chen

Front Immunol· October 2024

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RN486, a Bruton's Tyrosine Kinase inhibitor, antagonizes multidrug resistance in ABCG2-overexpressing cancer cells.
Xing-Duo Dong, Qisi Lu, Yi-Dong Li, Chao-Yun Cai, Qiu-Xu Teng

J Transl Int Med· June 2024

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Multidrug resistance transporters P-gp and BCRP limit the efficacy of ATR inhibitor ceralasertib in cancer cells.
Xuan-Yu Chen, Zhuo-Xun Wu, Jing-Quan Wang, Qiu-Xu Teng, Hailin Tang

Front Pharmacol· May 2024

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Overexpression of ABCC1 and ABCG2 confers resistance to talazoparib, a poly (ADP-Ribose) polymerase inhibitor.
Qiu-Xu Teng, Zi-Ning Lei, Jing-Quan Wang, Yuqi Yang, Zhuo-Xun Wu

Drug Resist Updat· March 2024

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ABCB1-dependent collateral sensitivity of multidrug-resistant colorectal cancer cells to the survivin inhibitor MX106-4C.
Zi-Ning Lei, Najah Albadari, Qiu-Xu Teng, Hadiar Rahman, Jing-Quan Wang

Drug Resist Updat· March 2024

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Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR.
Yuval Bin Kanner, Qiu-Xu Teng, Assaf Ganoth, Dan Peer, Jing-Quan Wang

Front Pharmacol· November 2023

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Design, synthesis, and biological evaluation of phenylurea indole derivatives as ABCG2 inhibitors.
Gao-Jie Ye, Chao-Yun Cai, Xing-Duo Dong, Zhuo-Xun Wu, Qiu-Xu Teng

Bioorg Chem· June 2023

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Understanding and targeting resistance mechanisms in cancer.
Zi-Ning Lei, Qin Tian, Qiu-Xu Teng, John N D Wurpel, Leli Zeng

MedComm (2020)· June 2023

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Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability.
Chao-Yun Cai, Qiu-Xu Teng, Megumi Murakami, Suresh V Ambudkar, Zhe-Sheng Chen

Biomolecules· January 2023

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Signaling pathways and therapeutic interventions in gastric cancer.
Zi-Ning Lei, Qiu-Xu Teng, Qin Tian, Wei Chen, Yuhao Xie

Signal Transduct Target Ther· October 2022

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Preclinical studies of the triazolo[1,5-]pyrimidine derivative WS-716 as a highly potent, specific and orally active P-glycoprotein (P-gp) inhibitor.
Sai-Qi Wang, Qiu-Xu Teng, Shuai Wang, Zi-Ning Lei, Hui-Hui Hu

Acta Pharm Sin B· August 2022

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Anticancer effect of Indanone-based thiazolyl hydrazone derivative on p53 mutant colorectal cancer cell lines: An and study.
Silpa Narayanan, Qiu-Xu Teng, Zhuo-Xun Wu, Urooj Nazim, Nishant Karadkhelkar

Front Oncol· August 2022

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MET inhibitor tepotinib antagonizes multidrug resistance mediated by ABCG2 transporter: and study.
Zhuo-Xun Wu, Qiu-Xu Teng, Yuqi Yang, Nikita Acharekar, Jing-Quan Wang

Acta Pharm Sin B· May 2022

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The Resistance of Cancer Cells to Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, is Mediated by the ABCB1 Transporter.
Han Fu, Zhuo-Xun Wu, Zi-Ning Lei, Qiu-Xu Teng, Yuqi Yang

Front Pharmacol· March 2022

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PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study.
Yuqi Yang, Qiu-Xu Teng, Zhuo-Xun Wu, Jing-Quan Wang, Zi-Ning Lei

Mol Cancer· February 2022

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Overexpression of ABCB1 Associated With the Resistance to the KRAS-G12C Specific Inhibitor ARS-1620 in Cancer Cells.
Xing-Duo Dong, Meng Zhang, Chao-Yun Cai, Qiu-Xu Teng, Jing-Quan Wang

Front Pharmacol· February 2022

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Overcoming multidrug resistance by knockout of ABCB1 gene using CRISPR/Cas9 system in SW620/Ad300 colorectal cancer cells.
Zi-Ning Lei, Qiu-Xu Teng, Zhuo-Xun Wu, Feng-Feng Ping, Peng Song

MedComm (2020)· December 2021

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Discovery of the Triazolo[1,5-]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance.
Shuai Wang, Sai-Qi Wang, Qiu-Xu Teng, Zi-Ning Lei, Zhe-Sheng Chen

J Med Chem· November 2021

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ATP-binding cassette (ABC) transporters in cancer: A review of recent updates.
Jing-Quan Wang, Zhuo-Xun Wu, Yuqi Yang, Qiu-Xu Teng, Yi-Dong Li

J Evid Based Med· September 2021

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VKNG-1 Antagonizes ABCG2-Mediated Multidrug Resistance via p-AKT and Bcl-2 Pathway in Colon Cancer: In Vitro and In Vivo Study.
Silpa Narayanan, Ying-Fang Fan, Nehaben A Gujarati, Qiu-Xu Teng, Jing-Quan Wang

Cancers (Basel)· September 2021

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CMP25, a synthetic new agent, targets multidrug resistance-associated protein 7 (MRP7/ABCC10).
Jing-Quan Wang, Bo Wang, Qiu-Xu Teng, Zi-Ning Lei, Yi-Dong Li

Biochem Pharmacol· August 2021

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Overexpression of ABCG2 Confers Resistance to MLN7243, a Ubiquitin-Activating Enzyme (UAE) Inhibitor.
Zhuo-Xun Wu, Yuqi Yang, Jing-Quan Wang, Silpa Narayanan, Zi-Ning Lei, Qiu-Xu Teng

Front Cell Dev Biol· July 2021

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Insights on the structure-function relationship of human multidrug resistance protein 7 (MRP7/ABCC10) from molecular dynamics simulations and docking studies.
Jing-Quan Wang, Qingbin Cui, Zi-Ning Lei, Qiu-Xu Teng, Ning Ji

MedComm (2020)· June 2021

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