Publications by authors named "Leona D Samson"

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Comprehensive Measurement of Inter-Individual Variation in DNA Repair Capacity in Healthy Individuals.
Ting Zhai, Patrizia Mazzucato, Catherine Ricciardi, David C Christiani, Liming Liang, Leona D Samson

Adv Sci (Weinh)· December 2025

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Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.
Lee J Pribyl, Jennifer E Kay, Joshua J Corrigan, Lindsay B Volk, Monét Norales, Leona D Samson

bioRxiv· October 2025

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Comprehensive Measurement of Inter-Individual Variation in DNA Repair Capacity in Healthy Individuals.
Ting Zhai, Patrizia Mazzucato, Catherine Ricciardi, David C Christiani, Liming Liang, Leona D Samson

medRxiv· June 2025

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Sex and Alkyladenine DNA Glycosylase Expression are Key Susceptibility Factors for NDMA-induced Mutations, Toxicity, and Cancer.
Jennifer E Kay, Joshua J Corrigan, Lindsay B Volk, Amanda L Armijo, Ilana S Nazari, Leona D Samson

bioRxiv· May 2025

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CometChip enables parallel analysis of multiple DNA repair activities [DNA repair 106 (2021) 103176-103202].
Jing Ge, Le P Ngo, Simran Kaushal, Ian J Tay, Elina Thadhani, Leona D Samson

DNA Repair (Amst)· June 2024

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Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory.
Diana L Bordin, Kayla Grooms, Nicola P Montaldo, Sarah L Fordyce Martin, Pål Sætrom, Leona D Samson

DNA Repair (Amst)· March 2024

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Molecular origins of mutational spectra produced by the environmental carcinogen -nitrosodimethylamine and S1 chemotherapeutic agents.
Amanda L Armijo, Pennapa Thongararm, Bogdan I Fedeles, Judy Yau, Jennifer E Kay, Leona D Samson

NAR Cancer· June 2023

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A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response.
Larissa Milano, Clara F Charlier, Rafaela Andreguetti, Thomas Cox, Eleanor Healing, Leona D Samson

Proc Natl Acad Sci U S A· March 2022

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CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage.
Le P Ngo, Simran Kaushal, Isaac A Chaim, Patrizia Mazzucato, Catherine Ricciardi, Leona D Samson

Free Radic Biol Med· October 2021

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CometChip enables parallel analysis of multiple DNA repair activities.
Jing Ge, Le P Ngo, Simran Kaushal, Ian J Tay, Elina Thadhani, Leona D Samson

DNA Repair (Amst)· October 2021

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The life and legacy of Sam Wilson (1939-2021).
Philip C Hanawalt, Leona D Samson, Bennett Van Houten

DNA Repair (Amst)· August 2021

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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice.
Jennifer E Kay, Joshua J Corrigan, Amanda L Armijo, Ilana S Nazari, Ishwar N Kohale, Leona D Samson

Cell Rep· March 2021

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Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates.
Le P Ngo, Norah A Owiti, Carol Swartz, John Winters, Yang Su, Leona D Samson

Nucleic Acids Res· February 2020

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Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression.
Nicola P Montaldo, Diana L Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L Fordyce Martin, Leona D Samson

Nat Commun· November 2019

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Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells.
Zachary D Nagel, Andrew A Beharry, Patrizia Mazzucato, Gaspar J Kitange, Jann N Sarkaria, Leona D Samson

PLoS One· October 2019

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Correction to: Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study.
Panida Navasumrit, Krittinee Chaisatra, Jeerawan Promvijit, Varabhorn Parnlob, Somchamai Waraprasit, Leona D Samson

Environ Health· July 2019

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Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study.
Panida Navasumrit, Krittinee Chaisatra, Jeerawan Promvijit, Varabhorn Parnlob, Somchamai Waraprasit, Leona D Samson

Environ Health· June 2019

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H. John F. Cairns (1922-2018).
Leona D Samson

Nat Struct Mol Biol· March 2019

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Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation.
Le P Ngo, Tze Khee Chan, Jing Ge, Leona D Samson, Bevin P Engelward

Cell Rep· February 2019

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Inflammation, necrosis, and the kinase RIP3 are key mediators of AAG-dependent alkylation-induced retinal degeneration.
Mariacarmela Allocca, Joshua J Corrigan, Aprotim Mazumder, Kimberly R Fake, Leona D Samson

Sci Signal· February 2019

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The human gut bacterial genotoxin colibactin alkylates DNA.
Matthew R Wilson, Yindi Jiang, Peter W Villalta, Alessia Stornetta, Paul D Boudreau, Leona D Samson

Science· February 2019

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A target to suppress inflammation.
Leona D Samson

Science· November 2018

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Nitric oxide induced S-nitrosation causes base excision repair imbalance.
Marcus C Parrish, Isaac A Chaim, Zachary D Nagel, Steven R Tannenbaum, Leona D Samson

DNA Repair (Amst)· August 2018

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ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade.
Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Leona D Samson

Nat Med· May 2018

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In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities.
Isaac A Chaim, Zachary D Nagel, Jennifer J Jordan, Patrizia Mazzucato, Le P Ngo, Leona D Samson

Proc Natl Acad Sci U S A· November 2017

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