Publications by authors named "Leonard D Goldstein"

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A semi-automated ASC speck assay to evaluate pyrin inflammasome activation.
Pei Dai, Oliver Skinner, Xufeng Lin, Aiden Telfser, Stephanie Ruiz-Diaz, Leonard D Goldstein

Clin Transl Immunology· October 2025

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Targeting the NPY/NPY1R signaling axis in mutant p53-dependent pancreatic cancer impairs metastasis.
Cecilia R Chambers, Supitchaya Watakul, Peter Schofield, Anna E Howell, Jessie Zhu, Leonard D Goldstein

Sci Adv· March 2025

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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Leonard D Goldstein

Sci Adv· July 2024

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ENTRAIN: integrating trajectory inference and gene regulatory networks with spatial data to co-localize the receptor-ligand interactions that specify cell fate.
Wunna Kyaw, Ryan C Chai, Weng Hua Khoo, Leonard D Goldstein, Peter I Croucher

Bioinformatics· December 2023

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Quantitative ctDNA Detection in Hepatoblastoma: Implications for Precision Medicine.
Smadar Kahana-Edwin, James Torpy, Lucy E Cain, Anna Mullins, Geoffrey McCowage, Leonard D Goldstein

Cancers (Basel)· December 2023

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Circulating Tumour DNA Biomarkers Associated with Outcomes in Metastatic Prostate Cancer Treated with Lutetium-177-PSMA-617.
Megan Crumbaker, Leonard D Goldstein, David H Murray, Jiang Tao, Sarennya Pathmanandavel

Eur Urol Open Sci· November 2023

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Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy.
Andrew O Yam, Jacqueline Bailey, Francis Lin, Arnolda Jakovija, Scott E Youlten, Leonard D Goldstein

Cancer Res· April 2023

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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration.
Luz D Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J Katschke, Rommel Arceo, Leonard D Goldstein

Cell Rep· March 2023

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Embryonic lethality and defective mammary gland development of activator-function impaired conditional knock-in mice.
Kate Senger, Wenlin Yuan, Meredith Sagolla, Jonas Doerr, Brad Bolon, Leonard D Goldstein

Adv Genet (Hoboken)· March 2021

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Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires.
Yi-Chun Hsiao, Ying-Jiun J Chen, Leonard D Goldstein, Jia Wu, Zhonghua Lin

MAbs· February 2021

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Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.
Filip Roudnicky, Jitao David Zhang, Bo Kyoung Kim, Nikhil J Pandya, Yanjun Lan, Leonard D Goldstein

Proc Natl Acad Sci U S A· August 2020

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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.
Akhilesh Pandey, Eric W Stawiski, Steffen Durinck, Harsha Gowda, Leonard D Goldstein

Nat Commun· August 2020

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Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies.
Leonard D Goldstein, Ying-Jiun J Chen, Jia Wu, Subhra Chaudhuri, Yi-Chun Hsiao

Commun Biol· April 2020

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Peripheral T cell expansion predicts tumour infiltration and clinical response.
Thomas D Wu, Shravan Madireddi, Patricia E de Almeida, Romain Banchereau, Ying-Jiun J Chen, Leonard D Goldstein

Nature· March 2020

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Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal.
Valeria Yartseva, Leonard D Goldstein, Julia Rodman, Lance Kates, Mark Z Chen

Cell Rep· February 2020

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The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins.
Kushal Suryamohan, Sajesh P Krishnankutty, Joseph Guillory, Matthew Jevit, Markus S Schröder, Leonard D Goldstein

Nat Genet· January 2020

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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration.
Luz D Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J Katschke, Rommel Arceo, Leonard D Goldstein

Cell Rep· January 2020

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S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis.
Wenlin Yuan, Leonard D Goldstein, Steffen Durinck, Ying-Jiun Chen, Thong T Nguyen

Breast Cancer Res· December 2019

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An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors.
Tao Wang, Rong Lu, Payal Kapur, Bijay S Jaiswal, Raquibul Hannan, Leonard D Goldstein

Cancer Discov· September 2018

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Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India.
Viswanathan Mohan, Venkatesan Radha, Thong T Nguyen, Eric W Stawiski, Kanika Bajaj Pahuja, Leonard D Goldstein

BMC Med Genet· February 2018

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Prediction and Quantification of Splice Events from RNA-Seq Data.
Leonard D Goldstein, Yi Cao, Gregoire Pau, Michael Lawrence, Thomas D Wu

PLoS One· July 2017

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Massively parallel nanowell-based single-cell gene expression profiling.
Leonard D Goldstein, Ying-Jiun Jasmine Chen, Jude Dunne, Alain Mir, Hermann Hubschle

BMC Genomics· July 2017

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Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers.
Leonard D Goldstein, James Lee, Florian Gnad, Christiaan Klijn, Annalisa Schaub

Cell Rep· September 2016

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