Publications by authors named "Thomas D Wu"

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Publisher Correction: TIGIT and PD-L1 co-blockade promotes clonal expansion of multipotent, non-exhausted antitumor T cells by facilitating co-stimulation.
Katherine Nutsch, Karl L Banta, Thomas D Wu, Charles W Tran, Stephanie Mittman

Nat Cancer· February 2025

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TIGIT and PD-L1 co-blockade promotes clonal expansion of multipotent, non-exhausted antitumor T cells by facilitating co-stimulation.
Katherine Nutsch, Karl L Banta, Thomas D Wu, Charles W Tran, Stephanie Mittman

Nat Cancer· December 2024

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ATF6 Promotes Colorectal Cancer Growth and Stemness by Regulating the Wnt Pathway.
Jeffrey J Rodvold, Matthew Grimmer, Karen Ruiz, Scot A Marsters, Ioanna Oikonomidi, Thomas D Wu

Cancer Res Commun· October 2024

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Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8 T cell responses.
Karl L Banta, Xiaozheng Xu, Avantika S Chitre, Amelia Au-Yeung, Chikara Takahashi, Thomas D Wu

Immunity· March 2022

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Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.
Adrien Le Thomas, Elena Ferri, Scot Marsters, Jonathan M Harnoss, David A Lawrence, Thomas D Wu

Nat Commun· December 2021

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Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies.
Amy A Lo, Andrew Wallace, Daniel Oreper, Nicolas Lounsbury, Charles Havnar, Thomas D Wu

J Immunother Cancer· October 2021

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Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade.
Romain Banchereau, Avantika S Chitre, Alexis Scherl, Thomas D Wu, Namrata S Patil

J Immunother Cancer· April 2021

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IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
Jonathan M Harnoss, Adrien Le Thomas, Mike Reichelt, Ofer Guttman, Thomas D Wu

Cancer Res· June 2020

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Peripheral T cell expansion predicts tumour infiltration and clinical response.
Thomas D Wu, Shravan Madireddi, Patricia E de Almeida, Romain Banchereau, Ying-Jiun J Chen

Nature· March 2020

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CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1.
Xiangnan Du, Patricia de Almeida, Nick Manieri, Denise de Almeida Nagata, Thomas D Wu

Proc Natl Acad Sci U S A· December 2018

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Prediction and Quantification of Splice Events from RNA-Seq Data.
Leonard D Goldstein, Yi Cao, Gregoire Pau, Michael Lawrence, Thomas D Wu

PLoS One· July 2017

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Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.
Ji Li, Nicola J Stagg, Jennifer Johnston, Michael J Harris, Sam A Menzies, Thomas D Wu

Cancer Cell· March 2017

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GMAP and GSNAP for Genomic Sequence Alignment: Enhancements to Speed, Accuracy, and Functionality.
Thomas D Wu, Jens Reeder, Michael Lawrence, Gabe Becker, Matthew J Brauer

Methods Mol Biol· December 2016

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Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody.
Ning Chai, Lee R Swem, Mike Reichelt, Haiyin Chen-Harris, Elizabeth Luis, Thomas D Wu

PLoS Pathog· June 2016

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Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.
Raphael Bueno, Eric W Stawiski, Leonard D Goldstein, Steffen Durinck, Assunta De Rienzo, Thomas D Wu

Nat Genet· April 2016

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Bitpacking techniques for indexing genomes: I. Hash tables.
Thomas D Wu

Algorithms Mol Biol· April 2016

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Bitpacking techniques for indexing genomes: II. Enhanced suffix arrays.
Thomas D Wu

Algorithms Mol Biol· April 2016

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A comprehensive transcriptional portrait of human cancer cell lines.
Christiaan Klijn, Steffen Durinck, Eric W Stawiski, Peter M Haverty, Zhaoshi Jiang, Thomas D Wu

Nat Biotechnol· March 2015

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Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.
Steffen Durinck, Eric W Stawiski, Andrea Pavía-Jiménez, Zora Modrusan, Payal Kapur, Thomas D Wu

Nat Genet· January 2015

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Diverse modes of genomic alteration in hepatocellular carcinoma.
Suchit Jhunjhunwala, Zhaoshi Jiang, Eric W Stawiski, Florian Gnad, Jinfeng Liu, Thomas D Wu

Genome Biol· August 2014

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Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Jinfeng Liu, Mark McCleland, Eric W Stawiski, Florian Gnad, Oleg Mayba, Thomas D Wu

Nat Commun· May 2014

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Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.
Jinfeng Liu, William Lee, Zhaoshi Jiang, Zhongqiang Chen, Suchit Jhunjhunwala, Thomas D Wu

Genome Res· December 2012

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Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.
Chaitali Parikh, Vasantharajan Janakiraman, Wen-I Wu, Catherine K Foo, Noelyn M Kljavin, Thomas D Wu, Jiansheng Wu

Proc Natl Acad Sci U S A· November 2012

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.
Charles M Rudin, Steffen Durinck, Eric W Stawiski, John T Poirier, Zora Modrusan, Thomas D Wu

Nat Genet· October 2012

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Recurrent R-spondin fusions in colon cancer.
Somasekar Seshagiri, Eric W Stawiski, Steffen Durinck, Zora Modrusan, Elaine E Storm, Thomas D Wu

Nature· August 2012

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