Publications by authors named "Lesley Mathews"

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Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression.
Ying Zhang, Stephanie M Cabarcas, J I Zheng, Lei Sun, Lesley A Mathews

Oncol Lett· June 2016

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Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity.
Lesley A Mathews, Jonathan M Keller, Crystal McKnight, Sam Michael, Paul Shinn

Curr Protoc Chem Biol· March 2015

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Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins.
Lavona Casson, Lauren Howell, Lesley A Mathews, Marc Ferrer, Noel Southall

PLoS One· August 2013

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Epigenetic regulation of SOX9 by the NF-κB signaling pathway in pancreatic cancer stem cells.
Lei Sun, Lesley A Mathews, Stephanie M Cabarcas, Xiaohu Zhang, Acong Yang

Stem Cells· August 2013

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The differentiation of pancreatic tumor-initiating cells by vitronectin can be blocked by cilengitide.
Stephanie M Cabarcas, Lei Sun, Lesley Mathews, Suneetha Thomas, Xiaohu Zhang

Pancreas· July 2013

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Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.
Garrett W Rhyasen, Lyndsey Bolanos, Jing Fang, Andres Jerez, Mark Wunderlich, Lesley Mathews

Cancer Cell· July 2013

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Genomic Analysis of Invasive Human Bone Marrow Derived Mesenchymal Stem Cells.
Lesley A Mathews, Elaine M Hurt, Xiaohu Zhang, William L Farrar

J Bone Marrow Res· May 2013

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A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.
Lesley A Mathews, Jonathan M Keller, Bonnie L Goodwin, Rajarshi Guha, Paul Shinn

J Biomol Screen· October 2012

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Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma.
Yibin Yang, Arthur L Shaffer, N C Tolga Emre, Michele Ceribelli, Meili Zhang, Lesley A Mathews

Cancer Cell· June 2012

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The cancer stem cell niche--there goes the neighborhood?
Stephanie M Cabarcas, Lesley A Mathews, William L Farrar

Int J Cancer· November 2011

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Increased expression of DNA repair genes in invasive human pancreatic cancer cells.
Lesley A Mathews, Stephanie M Cabarcas, Elaine M Hurt, Xiaohu Zhang, Elizabeth M Jaffee

Pancreas· July 2011

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DNA repair: the culprit for tumor-initiating cell survival?
Lesley A Mathews, Stephanie M Cabarcas, William L Farrar

Cancer Metastasis Rev· June 2011

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Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer.
Francesco Crea, Elaine M Hurt, Lesley A Mathews, Stephanie M Cabarcas, Lei Sun

Mol Cancer· April 2011

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Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells.
Lesley A Mathews, Elaine M Hurt, Xiaohu Zhang, William L Farrar

Mol Cancer· October 2010

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Targeting prostate cancer stem cells.
Francesco Crea, Lesley A Mathews, William L Farrar, Elaine M Hurt

Anticancer Agents Med Chem· December 2009

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Epigenetic gene regulation in stem cells and correlation to cancer.
Lesley A Mathews, Francesco Crea, W L Farrar

Differentiation· July 2009

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Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature.
George J Klarmann, Elaine M Hurt, Lesley A Mathews, Xiaohu Zhang, Maria A Duhagon

Clin Exp Metastasis· June 2009

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Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity.
Shaolei Lu, Klaus A Becker, Mary J Hagen, Haoheng Yan, Amy L Roberts, Lesley A Mathews

Endocrinology· October 2008

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Insulin-like growth factor-I inhibits growth regulatory responses engaged by estrogen and progesterone in the mouse mammary gland.
Lesley Mathews, Sallie Smith Schneider

Eur J Cancer Prev· August 2008

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Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies.
Monica M Mita, Alain C Mita, Quincy S Chu, Eric K Rowinsky, Gerald J Fetterly, Lesley Mathews

J Clin Oncol· January 2008

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Estrogen and progesterone regulate radiation-induced p53 activity in mammary epithelium through TGF-beta-dependent pathways.
Klaus A Becker, Shaolei Lu, Ellen S Dickinson, Karen A Dunphy, Lesley Mathews

Oncogene· September 2005

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